81 items (Exophiala spinifera) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	PV08_00888	3-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
	PV08_07986	Uncharacterized protein. (273 aa)
	PV08_00855	Dihydroorotate dehydrogenase (Fumarate). (616 aa)
	ADK1	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (279 aa)
	PV08_01903	ATP synthase subunit gamma. (297 aa)
	PV08_02013	Zn(2)-C6 fungal-type domain-containing protein. (664 aa)
	PV08_08960	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
	PV08_05324	Uncharacterized protein. (366 aa)
	PV08_05769	Acetyl-coenzyme A synthetase. (670 aa)
	PV08_05809	Uncharacterized protein. (2293 aa)
	PV08_06497	Uncharacterized protein. (2032 aa)
	PV08_03887	Uncharacterized protein. (246 aa)
	PV08_02321	Probable acetate kinase. (421 aa)
	PV08_03633	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
	PV08_00192	Orotate phosphoribosyltransferase. (244 aa)
	PV08_00374	Uncharacterized protein. (127 aa)
	PV08_01019	ATP synthase subunit delta, mitochondrial. (165 aa)
	PV08_01463	ATP synthase F1, delta subunit. (224 aa)
	PV08_01754	T5orf172 domain-containing protein. (778 aa)
	PV08_01884	Uncharacterized protein. (119 aa)
	PV08_08923	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
	PV08_08490	Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. (352 aa)
	PV08_09543	Uncharacterized protein. (76 aa)
	PV08_09135	Protein pyrABCN. (2297 aa)
	PV08_10697	3-carboxy-cis,cis-muconate cycloisomerase. (450 aa)
	PV08_11239	Uracil phosphoribosyltransferase. (248 aa)
	PV08_01641	Uracil phosphoribosyltransferase. (216 aa)
	PV08_01961	Dephospho-CoA kinase. (284 aa)
	PV08_01207	Amidophosphoribosyltransferase. (597 aa)
	PV08_03150	Uncharacterized protein. (203 aa)
	PV08_02951	GMP synthase [glutamine-hydrolyzing]. (545 aa)
	PV08_02996	Phosphoribosylformylglycinamidine synthase. (1381 aa)
	PV08_03031	Zn(2)-C6 fungal-type domain-containing protein. (711 aa)
	PV08_00792	AMP deaminase. (1045 aa)
	PV08_00912	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (556 aa)
	PV08_01007	Uncharacterized protein. (425 aa)
	PV08_01491	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (273 aa)
	PV08_06511	Flavoprotein domain-containing protein. (583 aa)
	PV08_06308	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
	PV08_06928	Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (305 aa)
	ADK2	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
	PV08_04192	Carbamoyl-phosphate synthase arginine-specific large chain. (1166 aa)
	PV08_06551	Pantothenate kinase. (441 aa)
	PV08_06262	Uncharacterized protein. (227 aa)
	PV08_07661	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (568 aa)
	PV08_07646	Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (607 aa)
	PV08_09608	Uncharacterized protein. (422 aa)
	PV08_09199	Uncharacterized protein. (205 aa)
	PV08_10771	Dihydroorotase, homodimeric type. (365 aa)
	PV08_06617	Formyltetrahydrofolate deformylase. (281 aa)
	PV08_01666	Uridine kinase; Belongs to the uridine kinase family. (465 aa)
	PV08_11232	Uncharacterized protein. (697 aa)
	PV08_10082	Flavokinase domain-containing protein. (217 aa)
	PV08_09211	Uncharacterized protein. (485 aa)
	PV08_09615	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (618 aa)
	PV08_09630	Uncharacterized protein. (420 aa)
	PV08_09815	Uncharacterized protein. (185 aa)
	PV08_08047	Uncharacterized protein. (120 aa)
	PV08_08462	Guanylate kinase. (207 aa)
	PV08_06656	ATP synthase subunit 4, mitochondrial. (244 aa)
	PV08_06909	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (503 aa)
	PV08_05489	Adenine phosphoribosyltransferase. (214 aa)
	PV08_05376	Uncharacterized protein. (60 aa)
	PV08_05873	Uracil phosphoribosyltransferase. (234 aa)
	PV08_05998	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa)
	PV08_05870	Uracil phosphoribosyltransferase. (202 aa)
	PV08_06548	CMP/dCMP-type deaminase domain-containing protein. (312 aa)
	PV08_03927	PfkB domain-containing protein. (338 aa)
	PV08_04500	Phosphoribosylamine-glycine ligase. (794 aa)
	PV08_04356	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (376 aa)
	PV08_04366	DOMON domain-containing protein. (479 aa)
	PV08_11155	Uncharacterized protein. (458 aa)
	PV08_05123	Fungal_trans domain-containing protein. (617 aa)
	PV08_04724	Phosphoribosylglycinamide formyltransferase. (246 aa)
	PV08_05010	Zn(2)-C6 fungal-type domain-containing protein. (686 aa)
	PV08_02596	V-type proton ATPase catalytic subunit A. (688 aa)
	PV08_02438	Nucleoside diphosphate kinase. (153 aa)
	PV08_02833	Uncharacterized protein. (356 aa)
	PV08_09500	Flavokinase domain-containing protein. (609 aa)
	PV08_09596	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (241 aa)
	PV08_00485	Uncharacterized protein. (58 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADK1	ADK2	A0A0D2BP55	A0A0D1YPF7	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.776
ADK1	PV08_00192	A0A0D2BP55	A0A0D2C7S4	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Orotate phosphoribosyltransferase.	0.508
ADK1	PV08_00792	A0A0D2BP55	A0A0D2A605	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	AMP deaminase.	0.826
ADK1	PV08_00888	A0A0D2BP55	A0A0D2BMZ4	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	3-carboxy-cis,cis-muconate cycloisomerase.	0.760
ADK1	PV08_00912	A0A0D2BP55	A0A0D2A6C2	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.859
ADK1	PV08_01019	A0A0D2BP55	A0A0D2CA60	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	ATP synthase subunit delta, mitochondrial.	0.670
ADK1	PV08_01463	A0A0D2BP55	A0A0D2CBH7	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	ATP synthase F1, delta subunit.	0.862
ADK1	PV08_01491	A0A0D2BP55	A0A0D2A804	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.	0.519
ADK1	PV08_01641	A0A0D2BP55	A0A0D2A8H6	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Uracil phosphoribosyltransferase.	0.424
ADK1	PV08_01666	A0A0D2BP55	A0A0D2A8J6	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Uridine kinase; Belongs to the uridine kinase family.	0.425
ADK1	PV08_01903	A0A0D2BP55	A0A0D2BQP7	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	ATP synthase subunit gamma.	0.915
ADK1	PV08_02013	A0A0D2BP55	A0A0D2BR09	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Zn(2)-C6 fungal-type domain-containing protein.	0.519
ADK1	PV08_02438	A0A0D2BP55	A0A0D2BHQ0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Nucleoside diphosphate kinase.	0.849
ADK1	PV08_02596	A0A0D2BP55	A0A0D2BH31	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	V-type proton ATPase catalytic subunit A.	0.680
ADK1	PV08_02951	A0A0D2BP55	A0A0D2A110	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	GMP synthase [glutamine-hydrolyzing].	0.668
ADK1	PV08_03031	A0A0D2BP55	A0A0D2A192	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Zn(2)-C6 fungal-type domain-containing protein.	0.519
ADK1	PV08_03633	A0A0D2BP55	A0A0D2C6Y5	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.669
ADK1	PV08_03887	A0A0D2BP55	A0A0D2BZF1	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Uncharacterized protein.	0.794
ADK1	PV08_03927	A0A0D2BP55	A0A0D2BCN1	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	PfkB domain-containing protein.	0.926
ADK1	PV08_05010	A0A0D2BP55	A0A0D2BGQ8	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Zn(2)-C6 fungal-type domain-containing protein.	0.519