95 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_05748	Uncharacterized protein. (522 aa)
	PV08_05793	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (456 aa)
	PV08_06049	Uncharacterized protein. (840 aa)
	PV08_05740	WD_REPEATS_REGION domain-containing protein. (519 aa)
	PV08_06441	Uncharacterized protein. (245 aa)
	PV08_04241	Uncharacterized protein. (1610 aa)
	PV08_04757	Uncharacterized protein. (1448 aa)
	PV08_05055	N-acetyltransferase domain-containing protein. (222 aa)
	PV08_02922	Histone deacetylase RPD3. (678 aa)
	PV08_10479	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (436 aa)
	PV08_03072	Deacetylase sirtuin-type domain-containing protein. (617 aa)
	PV08_03303	WD_REPEATS_REGION domain-containing protein. (476 aa)
	PV08_03139	rRNA 2'-O-methyltransferase fibrillarin. (324 aa)
	PV08_03290	Hist_deacetyl domain-containing protein. (367 aa)
	PV08_00095	CDC73_C domain-containing protein. (444 aa)
	PV08_09152	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (818 aa)
	PV08_00203	Uncharacterized protein. (193 aa)
	PV08_00535	Uncharacterized protein. (664 aa)
	PV08_01113	Non-specific serine/threonine protein kinase. (874 aa)
	PV08_08056	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3807 aa)
	PV08_00915	Uncharacterized protein. (476 aa)
	PV08_00925	Uncharacterized protein. (453 aa)
	PV08_01150	Uncharacterized protein. (409 aa)
	PV08_01657	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (554 aa)
	PV08_01873	Uncharacterized protein. (551 aa)
	PV08_01433	FAS1 domain-containing protein. (239 aa)
	PV08_06232	Uncharacterized protein. (686 aa)
	PV08_06112	Uncharacterized protein. (529 aa)
	PV08_06006	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (492 aa)
	PV08_05700	MRG domain-containing protein. (324 aa)
	PV08_05664	Uncharacterized protein. (245 aa)
	PV08_05584	E3 ubiquitin protein ligase. (705 aa)
	PV08_05527	SET domain-containing protein. (433 aa)
	PV08_07798	Uncharacterized protein. (775 aa)
	PV08_06852	SGF29 C-terminal domain-containing protein. (318 aa)
	PV08_08872	SET domain-containing protein. (396 aa)
	PV08_09558	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (473 aa)
	PV08_10801	USP domain-containing protein; Belongs to the peptidase C19 family. (498 aa)
	PV08_11580	Uncharacterized protein. (613 aa)
	PV08_07428	WD_REPEATS_REGION domain-containing protein. (537 aa)
	PV08_07694	SET domain-containing protein. (935 aa)
	PV08_05224	Uncharacterized protein. (490 aa)
	PV08_05989	Uncharacterized protein. (871 aa)
	PV08_06435	Deacetylase sirtuin-type domain-containing protein. (605 aa)
	PV08_04430	Uncharacterized protein. (994 aa)
	PV08_04859	Bromo domain-containing protein. (1169 aa)
	PV08_03008	HDAC_interact domain-containing protein. (1515 aa)
	PV08_03248	RING-type domain-containing protein. (290 aa)
	PV08_00126	Uncharacterized protein. (645 aa)
	PV08_00202	Uncharacterized protein. (490 aa)
	PV08_00404	Uncharacterized protein. (540 aa)
	PV08_00664	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (965 aa)
	PV08_02129	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2916 aa)
	PV08_03770	Uncharacterized protein. (380 aa)
	PV08_07874	HAD_SAK_1 domain-containing protein. (568 aa)
	PV08_09734	SET domain-containing protein. (177 aa)
	PV08_09594	Uncharacterized protein. (1366 aa)
	PV08_09180	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (241 aa)
	PV08_10276	Serine/threonine-protein kinase ark1; Belongs to the protein kinase superfamily. (417 aa)
	PV08_09832	Uncharacterized protein. (357 aa)
	PV08_09911	Uncharacterized protein. (271 aa)
	PV08_09810	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
	PV08_09479	Histone acetyltransferase. (532 aa)
	PV08_09277	Uncharacterized protein. (247 aa)
	PV08_09267	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (538 aa)
	PV08_09257	WD_REPEATS_REGION domain-containing protein. (354 aa)
	PV08_09186	Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (830 aa)
	PV08_10354	RBR-type E3 ubiquitin transferase. (514 aa)
	PV08_10142	SET domain-containing protein. (767 aa)
	PV08_11362	UBIQUITIN_CONJUGAT_2 domain-containing protein. (331 aa)
	PV08_11169	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (285 aa)
	PV08_11926	Ribosomal protein L32. (417 aa)
	PV08_12104	Deacetylase sirtuin-type domain-containing protein. (427 aa)
	PV08_02435	Uncharacterized protein. (380 aa)
	PV08_04681	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1278 aa)
	PV08_04203	Post-SET domain-containing protein. (181 aa)
	PV08_08613	RXT2_N domain-containing protein. (527 aa)
	PV08_10091	PHD-type domain-containing protein. (1142 aa)
	PV08_11108	SET domain-containing protein. (461 aa)
	PV08_11753	Uncharacterized protein. (853 aa)
	PV08_12103	SET domain-containing protein. (279 aa)
	PV08_01136	Uncharacterized protein. (419 aa)
	PV08_01121	Uncharacterized protein. (1215 aa)
	PV08_00921	Thioredoxin-like_fold domain-containing protein. (210 aa)
	PV08_03070	Uncharacterized protein. (656 aa)
	PV08_02879	SANT domain-containing protein. (797 aa)
	PV08_04498	Actin, gamma. (375 aa)
	PV08_04016	Uncharacterized protein. (548 aa)
	PV08_06478	Non-specific serine/threonine protein kinase. (872 aa)
	PV08_06919	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1311 aa)
	PV08_07822	Uncharacterized protein. (428 aa)
	PV08_07309	DUF3591 domain-containing protein. (1129 aa)
	PV08_05225	Uncharacterized protein. (1737 aa)
	PV08_07006	Chromatin modification-related protein. (767 aa)
	PV08_05671	Uncharacterized protein; Belongs to the actin family. (475 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00095	PV08_00404	A0A0D2BKS5	A0A0D2C8E2	CDC73_C domain-containing protein.	Uncharacterized protein.	0.999
PV08_00095	PV08_00664	A0A0D2BKS5	A0A0D2C958	CDC73_C domain-containing protein.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.562
PV08_00095	PV08_01121	A0A0D2BKS5	A0A0D1YZ56	CDC73_C domain-containing protein.	Uncharacterized protein.	0.999
PV08_00095	PV08_02922	A0A0D2BKS5	A0A0D2BI47	CDC73_C domain-containing protein.	Histone deacetylase RPD3.	0.672
PV08_00095	PV08_03290	A0A0D2BKS5	A0A0D2BKD0	CDC73_C domain-containing protein.	Hist_deacetyl domain-containing protein.	0.651
PV08_00095	PV08_03303	A0A0D2BKS5	A0A0D2BJF3	CDC73_C domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.421
PV08_00095	PV08_04681	A0A0D2BKS5	A0A0D1ZXY9	CDC73_C domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.496
PV08_00095	PV08_05224	A0A0D2BKS5	A0A0D2BV93	CDC73_C domain-containing protein.	Uncharacterized protein.	0.999
PV08_00095	PV08_05584	A0A0D2BKS5	A0A0D1YKN5	CDC73_C domain-containing protein.	E3 ubiquitin protein ligase.	0.889
PV08_00095	PV08_09152	A0A0D2BKS5	A0A0D2BKW0	CDC73_C domain-containing protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.651
PV08_00095	PV08_09810	A0A0D2BKS5	A0A0D2B0X7	CDC73_C domain-containing protein.	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.	0.789
PV08_00095	PV08_11362	A0A0D2BKS5	A0A0D2AVB5	CDC73_C domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.762
PV08_00095	PV08_11580	A0A0D2BKS5	A0A0D1Y6W4	CDC73_C domain-containing protein.	Uncharacterized protein.	0.969
PV08_00095	PV08_11753	A0A0D2BKS5	A0A0D1ZAG2	CDC73_C domain-containing protein.	Uncharacterized protein.	0.437
PV08_00095	PV08_11926	A0A0D2BKS5	A0A0D2ATH4	CDC73_C domain-containing protein.	Ribosomal protein L32.	0.999
PV08_00126	PV08_01136	A0A0D2C7N6	A0A0D1YZ66	Uncharacterized protein.	Uncharacterized protein.	0.961
PV08_00126	PV08_01150	A0A0D2C7N6	A0A0D2BPZ9	Uncharacterized protein.	Uncharacterized protein.	0.968
PV08_00126	PV08_03070	A0A0D2C7N6	A0A0D1YU43	Uncharacterized protein.	Uncharacterized protein.	0.657
PV08_00126	PV08_03248	A0A0D2C7N6	A0A0D2C5Z3	Uncharacterized protein.	RING-type domain-containing protein.	0.649
PV08_00126	PV08_04859	A0A0D2C7N6	A0A0D2C1Y9	Uncharacterized protein.	Bromo domain-containing protein.	0.988