STRINGSTRING
PV08_00951 PV08_00951 PV08_00192 PV08_00192 PV08_06185 PV08_06185 PV08_01710 PV08_01710 PV08_05870 PV08_05870 PV08_06099 PV08_06099 PV08_05489 PV08_05489 PV08_07678 PV08_07678 PV08_08616 PV08_08616 PV08_01641 PV08_01641 PV08_00817 PV08_00817 PV08_02590 PV08_02590 PV08_02490 PV08_02490 PV08_04912 PV08_04912 PV08_07587 PV08_07587 PV08_08399 PV08_08399 PV08_01207 PV08_01207 PV08_07058 PV08_07058 PV08_09199 PV08_09199
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV08_00951Uncharacterized protein. (467 aa)
PV08_00192Orotate phosphoribosyltransferase. (244 aa)
PV08_06185Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (562 aa)
PV08_01710Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (337 aa)
PV08_05870Uracil phosphoribosyltransferase. (202 aa)
PV08_06099CAP10 domain-containing protein. (595 aa)
PV08_05489Adenine phosphoribosyltransferase. (214 aa)
PV08_07678S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (314 aa)
PV08_08616BRCT domain-containing protein. (560 aa)
PV08_01641Uracil phosphoribosyltransferase. (216 aa)
PV08_00817Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (407 aa)
PV08_02590Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (314 aa)
PV08_02490Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (465 aa)
PV08_04912ATP phosphoribosyltransferase. (317 aa)
PV08_07587Uncharacterized protein. (1201 aa)
PV08_08399Anthranilate phosphoribosyltransferase. (423 aa)
PV08_01207Amidophosphoribosyltransferase. (597 aa)
PV08_07058Uncharacterized protein. (323 aa)
PV08_09199Uncharacterized protein. (205 aa)
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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