55 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_02926	F-box domain-containing protein. (1204 aa)
	PV08_10938	Fungal_trans domain-containing protein. (856 aa)
	PV08_08448	Elongation of fatty acids protein. (353 aa)
	PV08_07540	Uncharacterized protein. (261 aa)
	PV08_03814	Uncharacterized protein. (98 aa)
	PV08_05056	Uncharacterized protein. (402 aa)
	PV08_02995	Elongation of fatty acids protein. (343 aa)
	PV08_09059	BZIP domain-containing protein. (243 aa)
	PV08_09200	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (100 aa)
	PV08_09689	Uncharacterized protein. (561 aa)
	PV08_08099	Uncharacterized protein. (412 aa)
	PV08_06653	Uncharacterized protein. (132 aa)
	PV08_07341	Uncharacterized protein. (593 aa)
	PV08_07859	Uncharacterized protein. (664 aa)
	MMM1	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (427 aa)
	PV08_06073	Uncharacterized protein. (485 aa)
	PV08_06218	Uncharacterized protein. (283 aa)
	PV08_06474	Uncharacterized protein. (973 aa)
	PV08_04338	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (171 aa)
	PV08_04721	Uncharacterized protein. (894 aa)
	PV08_02364	Uncharacterized protein. (236 aa)
	PV08_02470	Uncharacterized protein. (328 aa)
	PV08_02550	DUF2012 domain-containing protein. (288 aa)
	PV08_00427	ER membrane protein complex subunit 4; Belongs to the EMC4 family. (181 aa)
	PV08_00577	Uncharacterized protein. (248 aa)
	PV08_01289	SUN domain-containing protein. (930 aa)
	PV08_11134	Uncharacterized protein. (599 aa)
	PV08_11381	Uncharacterized protein. (401 aa)
	PV08_11439	Uncharacterized protein. (435 aa)
	PV08_09196	Uncharacterized protein. (446 aa)
	PV08_09317	Uncharacterized protein. (574 aa)
	PV08_09423	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (480 aa)
	PV08_09926	MSP domain-containing protein. (267 aa)
	PV08_06635	Uncharacterized protein. (443 aa)
	PV08_07414	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1320 aa)
	PV08_05293	Uncharacterized protein. (352 aa)
	PV08_06522	Uncharacterized protein. (413 aa)
	PV08_03816	Uncharacterized protein. (424 aa)
	PV08_04803	Uncharacterized protein. (234 aa)
	PV08_04599	Uncharacterized protein. (295 aa)
	PV08_04820	Uncharacterized protein. (1186 aa)
	PV08_02786	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (394 aa)
	PV08_03197	Elongation of fatty acids protein. (742 aa)
	PV08_09348	ANK_REP_REGION domain-containing protein. (1379 aa)
	PV08_09581	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (471 aa)
	PV08_01356	SAC domain-containing protein. (711 aa)
	PV08_08286	Uncharacterized protein. (118 aa)
	PV08_01448	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (265 aa)
	PV08_02133	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (239 aa)
	PV08_07664	RING-CH-type domain-containing protein. (1522 aa)
	PV08_04270	Uncharacterized protein. (434 aa)
	PV08_04984	TPR_REGION domain-containing protein. (405 aa)
	PV08_02427	PIG-P domain-containing protein. (520 aa)
	PV08_02467	acidPPc domain-containing protein. (234 aa)
	PV08_01144	EMC1_C domain-containing protein. (961 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00427	PV08_00577	A0A0D2A4U9	A0A0D2A5J2	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	Uncharacterized protein.	0.950
PV08_00427	PV08_01144	A0A0D2A4U9	A0A0D2CAH8	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	EMC1_C domain-containing protein.	0.988
PV08_00427	PV08_01448	A0A0D2A4U9	A0A0D2BQY4	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.993
PV08_00427	PV08_02550	A0A0D2A4U9	A0A0D1ZZV1	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	DUF2012 domain-containing protein.	0.971
PV08_00427	PV08_03814	A0A0D2A4U9	A0A0D1YNG6	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	Uncharacterized protein.	0.429
PV08_00427	PV08_04984	A0A0D2A4U9	A0A0D2C2B1	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	TPR_REGION domain-containing protein.	0.990
PV08_00427	PV08_06653	A0A0D2A4U9	A0A0D1ZM07	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	Uncharacterized protein.	0.980
PV08_00427	PV08_07540	A0A0D2A4U9	A0A0D1YIJ0	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	Uncharacterized protein.	0.944
PV08_00427	PV08_08286	A0A0D2A4U9	A0A0D2BPQ7	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	Uncharacterized protein.	0.879
PV08_00577	PV08_00427	A0A0D2A5J2	A0A0D2A4U9	Uncharacterized protein.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.950
PV08_00577	PV08_01144	A0A0D2A5J2	A0A0D2CAH8	Uncharacterized protein.	EMC1_C domain-containing protein.	0.947
PV08_00577	PV08_01448	A0A0D2A5J2	A0A0D2BQY4	Uncharacterized protein.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.945
PV08_00577	PV08_02550	A0A0D2A5J2	A0A0D1ZZV1	Uncharacterized protein.	DUF2012 domain-containing protein.	0.961
PV08_00577	PV08_04984	A0A0D2A5J2	A0A0D2C2B1	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.952
PV08_00577	PV08_06653	A0A0D2A5J2	A0A0D1ZM07	Uncharacterized protein.	Uncharacterized protein.	0.861
PV08_00577	PV08_07540	A0A0D2A5J2	A0A0D1YIJ0	Uncharacterized protein.	Uncharacterized protein.	0.861
PV08_01144	PV08_00427	A0A0D2CAH8	A0A0D2A4U9	EMC1_C domain-containing protein.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.988
PV08_01144	PV08_00577	A0A0D2CAH8	A0A0D2A5J2	EMC1_C domain-containing protein.	Uncharacterized protein.	0.947
PV08_01144	PV08_01448	A0A0D2CAH8	A0A0D2BQY4	EMC1_C domain-containing protein.	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.988
PV08_01144	PV08_02550	A0A0D2CAH8	A0A0D1ZZV1	EMC1_C domain-containing protein.	DUF2012 domain-containing protein.	0.956