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COQ4 COQ4 COQ3 COQ3 PV08_02187 PV08_02187 PV08_06736 PV08_06736 PV08_10787 PV08_10787 COQ5 COQ5 PV08_02562 PV08_02562 PV08_03989 PV08_03989 PV08_05587 PV08_05587 PV08_09905 PV08_09905 PV08_05478 PV08_05478 PV08_06403 PV08_06403 PV08_03901 PV08_03901 PV08_02805 PV08_02805 PV08_00360 PV08_00360 PV08_03582 PV08_03582 COQ6 COQ6 COQ7 COQ7 PV08_02469 PV08_02469
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COQ4Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (304 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (364 aa)
PV08_02187Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (835 aa)
PV08_06736Uncharacterized protein. (404 aa)
PV08_10787PRELI/MSF1 domain-containing protein. (245 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (303 aa)
PV08_02562Methyltransf_25 domain-containing protein. (243 aa)
PV08_03989Chaperone DnaJ. (543 aa)
PV08_05587ABC1 domain-containing protein. (782 aa)
PV08_09905COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (160 aa)
PV08_05478zf-Mss51 domain-containing protein. (521 aa)
PV08_06403Uncharacterized protein. (358 aa)
PV08_03901FAD-binding FR-type domain-containing protein. (426 aa)
PV08_02805Uncharacterized protein. (529 aa)
PV08_00360Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (469 aa)
PV08_03582Uncharacterized protein. (78 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (533 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (267 aa)
PV08_02469Uncharacterized protein. (350 aa)
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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