56 items (Exophiala spinifera) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PV08_10646	Fungal_trans domain-containing protein. (577 aa)
	PV08_01688	Uncharacterized protein. (360 aa)
	PV08_01205	RNase_PH domain-containing protein. (363 aa)
	PV08_03588	Uncharacterized protein. (83 aa)
	PV08_04531	PUM-HD domain-containing protein. (890 aa)
	PV08_05804	Tr-type G domain-containing protein. (702 aa)
	PV08_01775	Tr-type G domain-containing protein. (637 aa)
	PV08_06745	WD_REPEATS_REGION domain-containing protein. (643 aa)
	PV08_09621	Uncharacterized protein. (453 aa)
	PV08_00518	RPOL4c domain-containing protein. (152 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (642 aa)
	PV08_10714	Uncharacterized protein. (629 aa)
	PV08_03127	Uncharacterized protein. (529 aa)
	PV08_02678	KH_dom_type_1 domain-containing protein. (246 aa)
	PV08_10398	Uncharacterized protein. (500 aa)
	PV08_02593	PUM-HD domain-containing protein. (992 aa)
	PV08_02811	NTP_transf_9 domain-containing protein. (163 aa)
	PV08_02468	RBR-type E3 ubiquitin transferase. (723 aa)
	PV08_02586	PUM-HD domain-containing protein. (741 aa)
	PV08_05008	Uncharacterized protein. (650 aa)
	PV08_03953	Zn(2)-C6 fungal-type domain-containing protein. (635 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1201 aa)
	PV08_07117	Uncharacterized protein. (268 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (175 aa)
	PV08_06654	Protein vts1. (611 aa)
	PV08_09645	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (423 aa)
	PV08_09232	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (361 aa)
	PV08_10720	NTP_transf_9 domain-containing protein. (266 aa)
	PV08_10354	RBR-type E3 ubiquitin transferase. (514 aa)
	PV08_10608	S1 motif domain-containing protein. (350 aa)
	PV08_10418	HRDC domain-containing protein. (822 aa)
	PV08_10077	Guanine nucleotide-binding protein subunit beta-like protein. (316 aa)
	PV08_11437	Uncharacterized protein. (2310 aa)
	PV08_11154	WD_REPEATS_REGION domain-containing protein. (580 aa)
	PV08_00962	Uncharacterized protein. (330 aa)
	PV08_00612	S1 domain-containing protein. (167 aa)
	PV08_03697	Uncharacterized protein. (610 aa)
	PV08_03982	Endo/exonuclease/phosphatase domain-containing protein. (687 aa)
	PV08_03870	Uncharacterized protein. (1467 aa)
	PV08_05573	Zn(2)-C6 fungal-type domain-containing protein. (668 aa)
	PV08_07552	Uncharacterized protein. (292 aa)
	PV08_07241	PAP-associated domain-containing protein. (1360 aa)
	PV08_06728	RNase_PH domain-containing protein. (267 aa)
	PV08_10101	Uncharacterized protein. (291 aa)
	PV08_02116	PAT1 domain-containing protein. (799 aa)
	PV08_01399	Fungal_trans domain-containing protein. (633 aa)
	PV08_03454	WD_REPEATS_REGION domain-containing protein. (611 aa)
	PV08_04121	Uncharacterized protein. (459 aa)
	PV08_05236	Uncharacterized protein. (1136 aa)
	PV08_07763	ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family. (512 aa)
	PV08_07515	Fe2OG dioxygenase domain-containing protein. (746 aa)
	PV08_07158	TYR_PHOSPHATASE_2 domain-containing protein. (646 aa)
	PV08_06847	RNase_PH domain-containing protein. (369 aa)
	PV08_08619	Uncharacterized protein. (714 aa)
	PV08_09240	Nudix hydrolase domain-containing protein. (897 aa)
	INT6	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (435 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
INT6	PV08_10077	A0A0D1Y7R4	A0A0D2AVL6	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Guanine nucleotide-binding protein subunit beta-like protein.	0.967
LSM1	PV08_00962	A0A0D2B6L3	A0A0D2A6I5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.817
LSM1	PV08_02116	A0A0D2B6L3	A0A0D1Z1M6	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	PAT1 domain-containing protein.	0.966
LSM1	PV08_02811	A0A0D2B6L3	A0A0D2BHY1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	NTP_transf_9 domain-containing protein.	0.809
LSM1	PV08_03982	A0A0D2B6L3	A0A0D1ZVP7	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Endo/exonuclease/phosphatase domain-containing protein.	0.427
LSM1	PV08_07552	A0A0D2B6L3	A0A0D1ZPL9	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.850
LSM1	PV08_07763	A0A0D2B6L3	A0A0D1YJ66	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family.	0.968
LSM1	PV08_09232	A0A0D2B6L3	A0A0D2AZ51	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.407
LSM1	PV08_09240	A0A0D2B6L3	A0A0D1YAL5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Nudix hydrolase domain-containing protein.	0.850
LSM1	PV08_10720	A0A0D2B6L3	A0A0D2AYE8	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	NTP_transf_9 domain-containing protein.	0.809
PAN2	PAN3	A0A0D2B707	A0A0D2BK82	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	0.999
PAN2	PV08_03697	A0A0D2B707	A0A0D2A3D3	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.422
PAN2	PV08_03982	A0A0D2B707	A0A0D1ZVP7	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Endo/exonuclease/phosphatase domain-containing protein.	0.785
PAN2	PV08_04121	A0A0D2B707	A0A0D1YP52	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	Uncharacterized protein.	0.526
PAN2	PV08_06728	A0A0D2B707	A0A0D1ZMA5	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	RNase_PH domain-containing protein.	0.417
PAN2	PV08_07763	A0A0D2B707	A0A0D1YJ66	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family.	0.464
PAN3	PAN2	A0A0D2BK82	A0A0D2B707	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	0.999
PAN3	PV08_03982	A0A0D2BK82	A0A0D1ZVP7	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	Endo/exonuclease/phosphatase domain-containing protein.	0.598
PAN3	PV08_04121	A0A0D2BK82	A0A0D1YP52	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	Uncharacterized protein.	0.454
PAN3	PV08_07763	A0A0D2BK82	A0A0D1YJ66	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]	ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family.	0.541