19 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_09759	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (117 aa)
	PV08_07724	Protein kinase domain-containing protein. (888 aa)
	PV08_01294	Uncharacterized protein. (211 aa)
	PV08_11146	Serine/threonine-protein kinase bur1. (655 aa)
	PV08_10937	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1421 aa)
	PV08_10718	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (697 aa)
	PV08_10374	Plus3 domain-containing protein. (611 aa)
	PV08_04305	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
	PV08_05224	Uncharacterized protein. (490 aa)
	PV08_07136	CYCLIN domain-containing protein; Belongs to the cyclin family. (410 aa)
	PV08_00095	CDC73_C domain-containing protein. (444 aa)
	PV08_02546	Protein kinase domain-containing protein. (992 aa)
	PV08_04770	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
	PV08_06005	CID domain-containing protein. (248 aa)
	PV08_07244	Uncharacterized protein. (707 aa)
	PV08_07242	Uncharacterized protein. (704 aa)
	PV08_08272	Uncharacterized protein. (396 aa)
	PV08_09645	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (423 aa)
	PV08_09208	Prefoldin, alpha subunit. (175 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00095	PV08_02546	A0A0D2BKS5	A0A0D2BGX8	CDC73_C domain-containing protein.	Protein kinase domain-containing protein.	0.603
PV08_00095	PV08_05224	A0A0D2BKS5	A0A0D2BV93	CDC73_C domain-containing protein.	Uncharacterized protein.	0.999
PV08_00095	PV08_07136	A0A0D2BKS5	A0A0D2BSU5	CDC73_C domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.469
PV08_00095	PV08_07244	A0A0D2BKS5	A0A0D2B708	CDC73_C domain-containing protein.	Uncharacterized protein.	0.417
PV08_00095	PV08_07724	A0A0D2BKS5	A0A0D1ZQ76	CDC73_C domain-containing protein.	Protein kinase domain-containing protein.	0.548
PV08_00095	PV08_09759	A0A0D2BKS5	A0A0D1ZHW4	CDC73_C domain-containing protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.951
PV08_00095	PV08_10374	A0A0D2BKS5	A0A0D2AXD5	CDC73_C domain-containing protein.	Plus3 domain-containing protein.	0.995
PV08_00095	PV08_10718	A0A0D2BKS5	A0A0D2AXI3	CDC73_C domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.588
PV08_00095	PV08_10937	A0A0D2BKS5	A0A0D2AYW6	CDC73_C domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.947
PV08_00095	PV08_11146	A0A0D2BKS5	A0A0D2AUK4	CDC73_C domain-containing protein.	Serine/threonine-protein kinase bur1.	0.751
PV08_02546	PV08_00095	A0A0D2BGX8	A0A0D2BKS5	Protein kinase domain-containing protein.	CDC73_C domain-containing protein.	0.603
PV08_02546	PV08_05224	A0A0D2BGX8	A0A0D2BV93	Protein kinase domain-containing protein.	Uncharacterized protein.	0.556
PV08_02546	PV08_06005	A0A0D2BGX8	A0A0D2BBJ1	Protein kinase domain-containing protein.	CID domain-containing protein.	0.971
PV08_02546	PV08_07136	A0A0D2BGX8	A0A0D2BSU5	Protein kinase domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.988
PV08_02546	PV08_07244	A0A0D2BGX8	A0A0D2B708	Protein kinase domain-containing protein.	Uncharacterized protein.	0.870
PV08_02546	PV08_09645	A0A0D2BGX8	A0A0D2B079	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.829
PV08_02546	PV08_09759	A0A0D2BGX8	A0A0D1ZHW4	Protein kinase domain-containing protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.792
PV08_02546	PV08_10374	A0A0D2BGX8	A0A0D2AXD5	Protein kinase domain-containing protein.	Plus3 domain-containing protein.	0.494
PV08_02546	PV08_10718	A0A0D2BGX8	A0A0D2AXI3	Protein kinase domain-containing protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.635
PV08_02546	PV08_10937	A0A0D2BGX8	A0A0D2AYW6	Protein kinase domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.503