(6 nodes) rDNA heterochromatin network (Exophiala spinifera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_07878	WD_REPEATS_REGION domain-containing protein. (533 aa)
	PV08_10773	Uncharacterized protein. (1582 aa)
	PV08_10670	HMG box domain-containing protein. (325 aa)
	PV08_03290	Hist_deacetyl domain-containing protein. (367 aa)
	PV08_09152	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (818 aa)
	PV08_08116	Deacetylase sirtuin-type domain-containing protein. (533 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_03290	PV08_08116	A0A0D2BKD0	A0A0D2BPB7	Hist_deacetyl domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.577
PV08_03290	PV08_10670	A0A0D2BKD0	A0A0D2AY76	Hist_deacetyl domain-containing protein.	HMG box domain-containing protein.	0.532
PV08_03290	PV08_10773	A0A0D2BKD0	A0A0D2AXR1	Hist_deacetyl domain-containing protein.	Uncharacterized protein.	0.615
PV08_08116	PV08_03290	A0A0D2BPB7	A0A0D2BKD0	Deacetylase sirtuin-type domain-containing protein.	Hist_deacetyl domain-containing protein.	0.577
PV08_08116	PV08_09152	A0A0D2BPB7	A0A0D2BKW0	Deacetylase sirtuin-type domain-containing protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.577
PV08_09152	PV08_08116	A0A0D2BKW0	A0A0D2BPB7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Deacetylase sirtuin-type domain-containing protein.	0.577
PV08_09152	PV08_10670	A0A0D2BKW0	A0A0D2AY76	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	HMG box domain-containing protein.	0.532
PV08_09152	PV08_10773	A0A0D2BKW0	A0A0D2AXR1	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.615
PV08_10670	PV08_03290	A0A0D2AY76	A0A0D2BKD0	HMG box domain-containing protein.	Hist_deacetyl domain-containing protein.	0.532
PV08_10670	PV08_09152	A0A0D2AY76	A0A0D2BKW0	HMG box domain-containing protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.532
PV08_10670	PV08_10773	A0A0D2AY76	A0A0D2AXR1	HMG box domain-containing protein.	Uncharacterized protein.	0.663
PV08_10773	PV08_03290	A0A0D2AXR1	A0A0D2BKD0	Uncharacterized protein.	Hist_deacetyl domain-containing protein.	0.615
PV08_10773	PV08_09152	A0A0D2AXR1	A0A0D2BKW0	Uncharacterized protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.615
PV08_10773	PV08_10670	A0A0D2AXR1	A0A0D2AY76	Uncharacterized protein.	HMG box domain-containing protein.	0.663