65 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_02841	Translation initiation factor RLI1. (604 aa)
	PV08_00719	Brix domain-containing protein. (382 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (459 aa)
	PV08_04904	WD_REPEATS_REGION domain-containing protein. (526 aa)
	PV08_04506	Uncharacterized protein. (195 aa)
	PV08_05490	Uncharacterized protein; Belongs to the DEAD box helicase family. (793 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (830 aa)
	PV08_02135	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (250 aa)
	PV08_02020	Uncharacterized protein. (362 aa)
	PV08_01564	Uncharacterized protein. (1823 aa)
	PV08_01474	Uncharacterized protein. (95 aa)
	PV08_01383	Uncharacterized protein. (451 aa)
	PV08_01652	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (428 aa)
	PV08_08351	HIT-type domain-containing protein. (458 aa)
	PV08_08236	Uncharacterized protein. (739 aa)
	PV08_00830	60S ribosomal protein L7. (253 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (248 aa)
	PV08_00334	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (761 aa)
	PV08_00294	60S ribosomal protein L33-A. (109 aa)
	PV08_09117	Ribosomal protein L24. (152 aa)
	PV08_10850	Uncharacterized protein. (575 aa)
	PV08_03084	Uncharacterized protein. (710 aa)
	PV08_03074	60S ribosomal protein L35. (128 aa)
	PV08_03064	Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. (217 aa)
	PV08_11346	Brix domain-containing protein. (451 aa)
	PV08_11750	60S ribosomal protein L5. (300 aa)
	PV08_04682	Uncharacterized protein. (146 aa)
	PV08_11970	Uncharacterized protein. (790 aa)
	PV08_04151	Uncharacterized protein. (399 aa)
	PV08_05980	60S ribosomal protein L8-B. (271 aa)
	PV08_06264	KOW domain-containing protein. (147 aa)
	PV08_05735	60S ribosomal protein L10-A. (223 aa)
	PV08_05658	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (188 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (781 aa)
	PV08_07785	CP-type G domain-containing protein. (549 aa)
	PV08_07317	Uncharacterized protein. (628 aa)
	PV08_08466	PUM-HD domain-containing protein. (685 aa)
	PV08_09264	Uncharacterized protein. (382 aa)
	PV08_09342	Brix domain-containing protein. (343 aa)
	PV08_11366	RRM domain-containing protein. (660 aa)
	PV08_01112	Uncharacterized protein. (482 aa)
	PV08_00857	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (659 aa)
	PV08_00787	Brix domain-containing protein. (457 aa)
	PV08_00622	Uncharacterized protein. (710 aa)
	PV08_00266	NUFIP1 domain-containing protein. (459 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (681 aa)
	PV08_03936	CP-type G domain-containing protein. (663 aa)
	PV08_05757	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4840 aa)
	PV08_07734	Uncharacterized protein. (551 aa)
	PV08_07597	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (315 aa)
	PV08_07531	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (266 aa)
	PV08_08244	TRASH domain-containing protein. (213 aa)
	PV08_02021	Uncharacterized protein. (261 aa)
	PV08_01786	Uncharacterized protein. (1153 aa)
	PV08_01665	Exonuclease domain-containing protein. (314 aa)
	PV08_01156	RAI1 domain-containing protein. (394 aa)
	PV08_02368	Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (702 aa)
	PV08_02348	Uncharacterized protein. (272 aa)
	PV08_04926	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (221 aa)
	PV08_04467	Protein MAK16; Belongs to the MAK16 family. (327 aa)
	PV08_03819	Ribosomal_L23eN domain-containing protein. (156 aa)
	PV08_07813	KOW domain-containing protein. (192 aa)
	PV08_07425	Ribosome biogenesis protein nsa2. (261 aa)
	PV08_09537	Uncharacterized protein. (355 aa)
	PV08_11782	Uncharacterized protein. (381 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERB1	NOP7	A0A0D2B947	A0A0D1ZYX1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
ERB1	PV08_00294	A0A0D2B947	A0A0D2BM87	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosomal protein L33-A.	0.931
ERB1	PV08_00334	A0A0D2B947	A0A0D2BME1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.805
ERB1	PV08_00719	A0A0D2B947	A0A0D2C992	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing protein.	0.987
ERB1	PV08_00787	A0A0D2B947	A0A0D2A600	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing protein.	0.976
ERB1	PV08_00830	A0A0D2B947	A0A0D2BNZ7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosomal protein L7.	0.996
ERB1	PV08_00857	A0A0D2B947	A0A0D2A660	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.996
ERB1	PV08_01112	A0A0D2B947	A0A0D2A715	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.613
ERB1	PV08_01383	A0A0D2B947	A0A0D2BQQ4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.628
ERB1	PV08_01564	A0A0D2B947	A0A0D2BRE7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.936
ERB1	PV08_01652	A0A0D2B947	A0A0D2BQ61	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.	0.748
ERB1	PV08_01665	A0A0D2B947	A0A0D1Z0G8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Exonuclease domain-containing protein.	0.602
ERB1	PV08_01786	A0A0D2B947	A0A0D1Z0Q9	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.744
ERB1	PV08_02020	A0A0D2B947	A0A0D2BSP0	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.778
ERB1	PV08_02021	A0A0D2B947	A0A0D1Z1B6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.781
ERB1	PV08_02135	A0A0D2B947	A0A0D2BT28	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.996
ERB1	PV08_02348	A0A0D2B947	A0A0D1YS63	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.884
ERB1	PV08_02368	A0A0D2B947	A0A0D1YS75	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.996
ERB1	PV08_02841	A0A0D2B947	A0A0D2BHZ4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Translation initiation factor RLI1.	0.402
ERB1	PV08_03064	A0A0D2B947	A0A0D2BJJ5	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.	0.712