38 items (Exophiala spinifera) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	PV08_00387	Uncharacterized protein. (557 aa)
	PV08_01226	Pyridoxine biosynthesis protein pyroA; Belongs to the PdxS/SNZ family. (328 aa)
	PV08_00529	Uncharacterized protein. (153 aa)
	PV08_02477	GTP cyclohydrolase I. (265 aa)
	PV08_04899	Dethiobiotin synthase. (834 aa)
	PV08_06290	Uncharacterized protein. (492 aa)
	PV08_07624	Hydroxyethylthiazole kinase. (532 aa)
	PV08_01710	Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (337 aa)
	PV08_00930	Glutamine amidotransferase type-1 domain-containing protein. (885 aa)
	PV08_09500	Flavokinase domain-containing protein. (609 aa)
	PV08_00418	Dihydropteroate synthase. (472 aa)
	PV08_09087	Pantoate-beta-alanine ligase. (391 aa)
	PV08_11543	Dihydroneopterin aldolase. (257 aa)
	PV08_04674	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (227 aa)
	PV08_04607	SGL domain-containing protein. (389 aa)
	PV08_06434	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (235 aa)
	PV08_06274	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (333 aa)
	PV08_05868	Uncharacterized protein. (458 aa)
	PV08_07590	NMT1 domain-containing protein. (341 aa)
	PV08_07545	Pyridoxal kinase. (340 aa)
	PV08_06854	GTP cyclohydrolase II. (425 aa)
	PV08_06844	Spermidine synthase; Belongs to the spermidine/spermine synthase family. (291 aa)
	PV08_08050	Pyridoxamine 5'-phosphate oxidase. (270 aa)
	PV08_09702	SGL domain-containing protein. (310 aa)
	PV08_09580	Biotin synthase. (406 aa)
	PV08_10082	Flavokinase domain-containing protein. (217 aa)
	PV08_00827	Phosphomethylpyrimidine kinase. (562 aa)
	PV08_00597	RibD_C domain-containing protein. (669 aa)
	PV08_00532	Amino_oxidase domain-containing protein. (550 aa)
	PV08_00004	Zn(2)-C6 fungal-type domain-containing protein. (701 aa)
	PV08_02359	S-adenosylmethionine decarboxylase proenzyme. (504 aa)
	PV08_10587	Zn(2)-C6 fungal-type domain-containing protein. (581 aa)
	PV08_11501	Riboflavin synthase, alpha subunit. (241 aa)
	PV08_03331	F-box domain-containing protein. (634 aa)
	PV08_04580	Pyridox_oxase_2 domain-containing protein. (290 aa)
	PV08_07626	Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2. (278 aa)
	PV08_11605	Uncharacterized protein. (347 aa)
	PV08_11233	Uncharacterized protein. (526 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00004	PV08_00827	A0A0D2A3G3	A0A0D2A636	Zn(2)-C6 fungal-type domain-containing protein.	Phosphomethylpyrimidine kinase.	0.835
PV08_00387	PV08_00597	A0A0D2A4Q9	A0A0D2A5K5	Uncharacterized protein.	RibD_C domain-containing protein.	0.608
PV08_00387	PV08_00827	A0A0D2A4Q9	A0A0D2A636	Uncharacterized protein.	Phosphomethylpyrimidine kinase.	0.580
PV08_00387	PV08_01226	A0A0D2A4Q9	A0A0D2CAP3	Uncharacterized protein.	Pyridoxine biosynthesis protein pyroA; Belongs to the PdxS/SNZ family.	0.704
PV08_00387	PV08_01710	A0A0D2A4Q9	A0A0D2BRU6	Uncharacterized protein.	Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]	0.779
PV08_00387	PV08_04674	A0A0D2A4Q9	A0A0D2BFW3	Uncharacterized protein.	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.469
PV08_00387	PV08_07545	A0A0D2A4Q9	A0A0D2B7V2	Uncharacterized protein.	Pyridoxal kinase.	0.827
PV08_00387	PV08_07626	A0A0D2A4Q9	A0A0D1YIS6	Uncharacterized protein.	Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2.	0.778
PV08_00387	PV08_08050	A0A0D2A4Q9	A0A0D2B1Q3	Uncharacterized protein.	Pyridoxamine 5'-phosphate oxidase.	0.761
PV08_00387	PV08_09580	A0A0D2A4Q9	A0A0D2AZZ9	Uncharacterized protein.	Biotin synthase.	0.438
PV08_00418	PV08_00930	A0A0D2BLM1	A0A0D2BPA8	Dihydropteroate synthase.	Glutamine amidotransferase type-1 domain-containing protein.	0.860
PV08_00418	PV08_02477	A0A0D2BLM1	A0A0D2C3I0	Dihydropteroate synthase.	GTP cyclohydrolase I.	0.980
PV08_00418	PV08_04674	A0A0D2BLM1	A0A0D2BFW3	Dihydropteroate synthase.	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.687
PV08_00418	PV08_06274	A0A0D2BLM1	A0A0D2BB37	Dihydropteroate synthase.	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate.	0.401
PV08_00418	PV08_09087	A0A0D2BLM1	A0A0D2BKL5	Dihydropteroate synthase.	Pantoate-beta-alanine ligase.	0.429
PV08_00532	PV08_06844	A0A0D2A5A2	A0A0D2B599	Amino_oxidase domain-containing protein.	Spermidine synthase; Belongs to the spermidine/spermine synthase family.	0.796
PV08_00597	PV08_00387	A0A0D2A5K5	A0A0D2A4Q9	RibD_C domain-containing protein.	Uncharacterized protein.	0.608
PV08_00597	PV08_00827	A0A0D2A5K5	A0A0D2A636	RibD_C domain-containing protein.	Phosphomethylpyrimidine kinase.	0.608
PV08_00597	PV08_01226	A0A0D2A5K5	A0A0D2CAP3	RibD_C domain-containing protein.	Pyridoxine biosynthesis protein pyroA; Belongs to the PdxS/SNZ family.	0.660
PV08_00597	PV08_01710	A0A0D2A5K5	A0A0D2BRU6	RibD_C domain-containing protein.	Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]	0.638