75 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_07212	Uncharacterized protein. (661 aa)
	PV08_00994	Uncharacterized protein. (179 aa)
	PV08_00744	Uncharacterized protein. (1788 aa)
	PV08_00684	Uncharacterized protein. (315 aa)
	PV08_00258	Protein kinase domain-containing protein. (1057 aa)
	PV08_02993	Uncharacterized protein. (1033 aa)
	PV08_02280	Uncharacterized protein. (369 aa)
	PV08_04305	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
	PV08_04255	zf-C3H1 domain-containing protein. (1292 aa)
	PV08_04185	Uncharacterized protein. (742 aa)
	PV08_03822	SMI1_KNR4 domain-containing protein. (531 aa)
	PV08_02150	Uncharacterized protein. (467 aa)
	PV08_06965	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (616 aa)
	PV08_01025	Uncharacterized protein. (295 aa)
	PV08_09761	Rav1p_C domain-containing protein. (1314 aa)
	PV08_09741	Uncharacterized protein. (200 aa)
	PV08_00092	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (474 aa)
	PV08_09358	Aldolase_II domain-containing protein. (286 aa)
	PV08_09152	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (818 aa)
	PV08_03290	Hist_deacetyl domain-containing protein. (367 aa)
	PV08_03597	Uncharacterized protein. (1051 aa)
	PV08_03127	Uncharacterized protein. (529 aa)
	PV08_03062	Uncharacterized protein. (287 aa)
	PV08_10398	Uncharacterized protein. (500 aa)
	PV08_10258	AAA domain-containing protein; Belongs to the AAA ATPase family. (422 aa)
	PV08_10118	Protein kinase domain-containing protein. (266 aa)
	PV08_02385	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (189 aa)
	PV08_04770	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
	PV08_05023	Uncharacterized protein. (658 aa)
	PV08_05008	Uncharacterized protein. (650 aa)
	PV08_04502	Uncharacterized protein. (1106 aa)
	PV08_04381	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (130 aa)
	PV08_04186	Small COPII coat GTPase sar1; Belongs to the small GTPase superfamily. SAR1 family. (201 aa)
	PV08_04020	CBFD_NFYB_HMF domain-containing protein. (159 aa)
	PV08_04088	GTP-binding protein rhoC. (278 aa)
	PV08_03917	PHD domain-containing protein. (575 aa)
	PV08_06159	Uncharacterized protein. (486 aa)
	PV08_05391	Uncharacterized protein. (1900 aa)
	PV08_07862	Ras-GAP domain-containing protein. (780 aa)
	PV08_07855	BAH domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1056 aa)
	PV08_07211	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (279 aa)
	PV08_06686	Adenylyl cyclase-associated protein; Belongs to the CAP family. (547 aa)
	PV08_08613	RXT2_N domain-containing protein. (527 aa)
	PV08_08312	AIP3 domain-containing protein. (1110 aa)
	PV08_08057	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (679 aa)
	PV08_09742	Uncharacterized protein. (959 aa)
	PV08_09645	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (423 aa)
	PV08_09474	Uncharacterized protein. (462 aa)
	PV08_10077	Guanine nucleotide-binding protein subunit beta-like protein. (316 aa)
	PV08_11392	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (466 aa)
	PV08_01586	Septum-promoting GTP-binding protein 1. (279 aa)
	PV08_00352	SAP30_Sin3_bdg domain-containing protein. (329 aa)
	PV08_02966	Uncharacterized protein. (1648 aa)
	PV08_04193	Uncharacterized protein. (817 aa)
	PV08_06198	Uncharacterized protein. (375 aa)
	PV08_05503	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa)
	PV08_06612	WD_REPEATS_REGION domain-containing protein. (626 aa)
	PV08_09341	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1171 aa)
	PV08_01061	Uncharacterized protein. (1773 aa)
	PV08_00260	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1262 aa)
	PV08_02449	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (275 aa)
	PV08_04906	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	PV08_04237	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (319 aa)
	PV08_04187	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
	PV08_03946	Zn(2)-C6 fungal-type domain-containing protein. (930 aa)
	PV08_06442	Spindle pole body component. (913 aa)
	PV08_06417	t-SNARE coiled-coil homology domain-containing protein. (344 aa)
	PV08_05336	Uncharacterized protein. (584 aa)
	PV08_07763	ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family. (512 aa)
	PV08_07430	Uncharacterized protein. (419 aa)
	PV08_07158	TYR_PHOSPHATASE_2 domain-containing protein. (646 aa)
	PV08_06636	Rab-GAP TBC domain-containing protein. (443 aa)
	PV08_08253	Uncharacterized protein. (750 aa)
	PV08_10090	Cell division control protein 42. (245 aa)
	PV08_11132	Uncharacterized protein. (640 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00092	PV08_00258	A0A0D2BLU8	A0A0D2C7X5	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Protein kinase domain-containing protein.	0.967
PV08_00092	PV08_01025	A0A0D2BLU8	A0A0D2BPJ9	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Uncharacterized protein.	0.950
PV08_00092	PV08_01586	A0A0D2BLU8	A0A0D2A8D1	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Septum-promoting GTP-binding protein 1.	0.956
PV08_00092	PV08_03597	A0A0D2BLU8	A0A0D2BK56	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Uncharacterized protein.	0.950
PV08_00092	PV08_04088	A0A0D2BLU8	A0A0D2BD59	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	GTP-binding protein rhoC.	0.514
PV08_00092	PV08_04187	A0A0D2BLU8	A0A0D1YPB4	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.896
PV08_00092	PV08_06636	A0A0D2BLU8	A0A0D1YFL4	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Rab-GAP TBC domain-containing protein.	0.949
PV08_00092	PV08_07158	A0A0D2BLU8	A0A0D1YHG9	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	TYR_PHOSPHATASE_2 domain-containing protein.	0.626
PV08_00092	PV08_08057	A0A0D2BLU8	A0A0D2B2M8	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.964
PV08_00092	PV08_10090	A0A0D2BLU8	A0A0D1Y7A2	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Cell division control protein 42.	0.475
PV08_00258	PV08_00092	A0A0D2C7X5	A0A0D2BLU8	Protein kinase domain-containing protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.967
PV08_00258	PV08_00260	A0A0D2C7X5	A0A0D1YWK6	Protein kinase domain-containing protein.	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.924
PV08_00258	PV08_01025	A0A0D2C7X5	A0A0D2BPJ9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.529
PV08_00258	PV08_01061	A0A0D2C7X5	A0A0D1YYY6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.562
PV08_00258	PV08_01586	A0A0D2C7X5	A0A0D2A8D1	Protein kinase domain-containing protein.	Septum-promoting GTP-binding protein 1.	0.978
PV08_00258	PV08_02150	A0A0D2C7X5	A0A0D2BT42	Protein kinase domain-containing protein.	Uncharacterized protein.	0.534
PV08_00258	PV08_02993	A0A0D2C7X5	A0A0D2C529	Protein kinase domain-containing protein.	Uncharacterized protein.	0.849
PV08_00258	PV08_03597	A0A0D2C7X5	A0A0D2BK56	Protein kinase domain-containing protein.	Uncharacterized protein.	0.963
PV08_00258	PV08_03822	A0A0D2C7X5	A0A0D2BZ97	Protein kinase domain-containing protein.	SMI1_KNR4 domain-containing protein.	0.403
PV08_00258	PV08_04088	A0A0D2C7X5	A0A0D2BD59	Protein kinase domain-containing protein.	GTP-binding protein rhoC.	0.615