STRINGSTRING
PV08_06106 PV08_06106 PV08_11982 PV08_11982 PV08_11570 PV08_11570 PV08_11630 PV08_11630 PV08_10050 PV08_10050 PV08_09199 PV08_09199 PV08_09245 PV08_09245 PV08_09260 PV08_09260 PV08_09527 PV08_09527 PV08_09608 PV08_09608 PV08_09738 PV08_09738 PV08_06777 PV08_06777 PV08_06912 PV08_06912 PV08_07033 PV08_07033 PV08_07646 PV08_07646 PV08_05437 PV08_05437 PV08_06142 PV08_06142 PV08_06262 PV08_06262 PV08_06551 PV08_06551 ADK2 ADK2 PV08_04372 PV08_04372 PV08_04771 PV08_04771 PV08_03150 PV08_03150 PV08_03195 PV08_03195 PV08_03686 PV08_03686 PV08_01207 PV08_01207 PV08_01212 PV08_01212 PV08_01961 PV08_01961 PV08_11254 PV08_11254 PV08_11339 PV08_11339 PV08_10136 PV08_10136 PV08_10321 PV08_10321 PV08_10697 PV08_10697 PV08_10924 PV08_10924 PV08_09356 PV08_09356 PV08_09427 PV08_09427 PV08_09528 PV08_09528 PV08_09543 PV08_09543 PV08_08923 PV08_08923 PV08_06617 PV08_06617 PV08_06928 PV08_06928 PV08_05872 PV08_05872 PV08_06188 PV08_06188 PV08_06308 PV08_06308 PV08_06511 PV08_06511 PV08_04601 PV08_04601 PV08_02951 PV08_02951 PV08_02996 PV08_02996 PV08_03536 PV08_03536 PV08_00602 PV08_00602 PV08_00792 PV08_00792 PV08_00912 PV08_00912 PV08_01007 PV08_01007 PV08_01395 PV08_01395 PV08_11873 PV08_11873 PV08_11774 PV08_11774 PV08_11232 PV08_11232 PV08_11597 PV08_11597 PV08_11429 PV08_11429 PV08_11479 PV08_11479 PV08_11504 PV08_11504 PV08_11529 PV08_11529 PV08_10212 PV08_10212 PV08_10347 PV08_10347 PV08_10535 PV08_10535 PV08_10610 PV08_10610 PV08_10856 PV08_10856 PV08_09151 PV08_09151 PV08_09211 PV08_09211 PV08_09615 PV08_09615 PV08_09630 PV08_09630 PV08_09466 PV08_09466 PV08_09607 PV08_09607 PV08_09815 PV08_09815 PV08_09901 PV08_09901 PV08_08002 PV08_08002 PV08_08047 PV08_08047 PV08_08247 PV08_08247 PV08_08462 PV08_08462 PV08_08836 PV08_08836 PV08_08891 PV08_08891 PV08_06656 PV08_06656 PV08_06884 PV08_06884 PV08_06909 PV08_06909 PV08_06836 PV08_06836 PV08_07347 PV08_07347 PV08_07319 PV08_07319 PV08_07678 PV08_07678 PV08_07830 PV08_07830 PV08_07895 PV08_07895 PV08_07680 PV08_07680 PV08_05210 PV08_05210 PV08_05489 PV08_05489 PV08_05376 PV08_05376 PV08_05998 PV08_05998 PV08_05719 PV08_05719 PV08_06069 PV08_06069 PV08_01909 PV08_01909 PV08_01884 PV08_01884 PV08_01754 PV08_01754 PV08_01709 PV08_01709 PV08_01498 PV08_01498 PV08_01463 PV08_01463 PV08_01069 PV08_01069 PV08_01019 PV08_01019 PV08_00374 PV08_00374 PV08_00323 PV08_00323 PV08_00197 PV08_00197 PV08_03633 PV08_03633 AAH1-2 AAH1-2 PV08_02867 PV08_02867 PV08_02386 PV08_02386 PV08_02321 PV08_02321 PV08_02301 PV08_02301 PV08_04969 PV08_04969 PV08_06497 PV08_06497 PV08_06050 PV08_06050 PV08_05809 PV08_05809 PV08_05789 PV08_05789 PV08_05769 PV08_05769 PV08_05718 PV08_05718 PV08_05324 PV08_05324 PV08_06905 PV08_06905 PV08_01775 PV08_01775 PV08_06760 PV08_06760 PV08_08960 PV08_08960 PV08_01983 PV08_01983 PV08_01913 PV08_01913 PV08_01903 PV08_01903 PV08_01677 PV08_01677 PV08_01401 PV08_01401 ADK1 ADK1 PV08_01214 PV08_01214 PV08_08026 PV08_08026 PV08_07986 PV08_07986 PV08_00888 PV08_00888 PV08_00485 PV08_00485 PV08_00553 PV08_00553 PV08_00052 PV08_00052 PV08_09328 PV08_09328 PV08_09288 PV08_09288 PV08_00191 PV08_00191 PV08_03554 PV08_03554 AAH1 AAH1 PV08_03109 PV08_03109 PV08_03343 PV08_03343 PV08_02848 PV08_02848 PV08_02833 PV08_02833 PV08_02713 PV08_02713 PV08_03037 PV08_03037 PV08_02866 PV08_02866 PV08_02438 PV08_02438 PV08_10193 PV08_10193 PV08_02302 PV08_02302 PV08_11633 PV08_11633 PV08_02596 PV08_02596 PV08_04749 PV08_04749 PV08_04724 PV08_04724 PV08_11281 PV08_11281 PV08_11251 PV08_11251 PV08_11155 PV08_11155 PV08_04416 PV08_04416 PV08_04366 PV08_04366 PV08_04356 PV08_04356 PV08_04331 PV08_04331 PV08_11955 PV08_11955 PV08_11920 PV08_11920 PV08_04115 PV08_04115 PV08_04500 PV08_04500 PV08_04389 PV08_04389 PV08_03927 PV08_03927 PV08_06351 PV08_06351 PV08_06236 PV08_06236
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV08_06106Uncharacterized protein. (421 aa)
PV08_11982Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (398 aa)
PV08_11570Allantoicase. (394 aa)
PV08_11630IU_nuc_hydro domain-containing protein. (355 aa)
PV08_10050Fungal_trans domain-containing protein. (600 aa)
PV08_09199Uncharacterized protein. (205 aa)
PV08_092453-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (469 aa)
PV08_09260OHCU_decarbox domain-containing protein. (187 aa)
PV08_09527Amidohydro-rel domain-containing protein. (270 aa)
PV08_09608Uncharacterized protein. (422 aa)
PV08_09738Uncharacterized protein. (156 aa)
PV08_06777Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (418 aa)
PV08_06912TauD domain-containing protein. (372 aa)
PV08_07033Phosphotransferase. (553 aa)
PV08_07646Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (607 aa)
PV08_05437Xanthine dehydrogenase, molybdopterin binding subunit. (1485 aa)
PV08_06142Zn(2)-C6 fungal-type domain-containing protein. (640 aa)
PV08_06262Uncharacterized protein. (227 aa)
PV08_06551Pantothenate kinase. (441 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
PV08_04372Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (301 aa)
PV08_04771Enolase. (438 aa)
PV08_03150Uncharacterized protein. (203 aa)
PV08_03195A_deaminase domain-containing protein. (614 aa)
PV08_03686Adenosine deaminase. (371 aa)
PV08_01207Amidophosphoribosyltransferase. (597 aa)
PV08_01212Uncharacterized protein. (459 aa)
PV08_01961Dephospho-CoA kinase. (284 aa)
PV08_11254TauD domain-containing protein. (394 aa)
PV08_11339Uncharacterized protein. (501 aa)
PV08_10136Uncharacterized protein. (473 aa)
PV08_103212,3-bisphosphoglycerate-independent phosphoglycerate mutase. (520 aa)
PV08_106973-carboxy-cis,cis-muconate cycloisomerase. (450 aa)
PV08_10924Guanine deaminase. (462 aa)
PV08_09356Phosphotransferase. (442 aa)
PV08_09427Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (237 aa)
PV08_09528Amidohydro-rel domain-containing protein. (245 aa)
PV08_09543Uncharacterized protein. (76 aa)
PV08_08923Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
PV08_06617Formyltetrahydrofolate deformylase. (281 aa)
PV08_06928Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (305 aa)
PV08_05872Pribosyltran_N domain-containing protein. (309 aa)
PV08_061884HBT domain-containing protein. (154 aa)
PV08_06308Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
PV08_06511Flavoprotein domain-containing protein. (583 aa)
PV08_04601Pyruvate kinase; Belongs to the pyruvate kinase family. (524 aa)
PV08_02951GMP synthase [glutamine-hydrolyzing]. (545 aa)
PV08_02996Phosphoribosylformylglycinamidine synthase. (1381 aa)
PV08_03536Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (454 aa)
PV08_00602Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (441 aa)
PV08_00792AMP deaminase. (1045 aa)
PV08_00912ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (556 aa)
PV08_01007Uncharacterized protein. (425 aa)
PV08_01395IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (388 aa)
PV08_11873Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (299 aa)
PV08_11774AMP-binding domain-containing protein. (702 aa)
PV08_11232Uncharacterized protein. (697 aa)
PV08_11597Pribosyltran_N domain-containing protein. (456 aa)
PV08_11429Uncharacterized protein. (461 aa)
PV08_11479Uncharacterized protein. (312 aa)
PV08_11504Zn(2)-C6 fungal-type domain-containing protein. (1004 aa)
PV08_11529Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
PV08_10212Lipoyl-binding domain-containing protein. (468 aa)
PV08_103475-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (130 aa)
PV08_105354HBT domain-containing protein. (151 aa)
PV08_10610Allantoinase. (557 aa)
PV08_10856Guanine deaminase. (406 aa)
PV08_09151Glyceraldehyde-3-phosphate dehydrogenase. (389 aa)
PV08_09211Uncharacterized protein. (485 aa)
PV08_09615Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (618 aa)
PV08_09630Uncharacterized protein. (420 aa)
PV08_09466Nudix hydrolase domain-containing protein. (458 aa)
PV08_09607Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (482 aa)
PV08_09815Uncharacterized protein. (185 aa)
PV08_09901Amidohydro-rel domain-containing protein. (500 aa)
PV08_08002Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
PV08_08047Uncharacterized protein. (120 aa)
PV08_08247Uncharacterized protein. (608 aa)
PV08_08462Guanylate kinase. (207 aa)
PV08_08836Uncharacterized protein. (325 aa)
PV08_08891Uncharacterized protein. (275 aa)
PV08_06656ATP synthase subunit 4, mitochondrial. (244 aa)
PV08_06884Guanine deaminase. (500 aa)
PV08_06909Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (503 aa)
PV08_06836Nudix hydrolase domain-containing protein. (158 aa)
PV08_07347Adenosine deaminase. (381 aa)
PV08_07319Phosphotransferase. (490 aa)
PV08_07678S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (314 aa)
PV08_07830Uncharacterized protein. (624 aa)
PV08_07895IU_nuc_hydro domain-containing protein. (365 aa)
PV08_07680Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (300 aa)
PV08_05210Uncharacterized protein. (319 aa)
PV08_05489Adenine phosphoribosyltransferase. (214 aa)
PV08_05376Uncharacterized protein. (60 aa)
PV08_05998Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa)
PV08_05719Zn(2)-C6 fungal-type domain-containing protein. (695 aa)
PV08_06069IU_nuc_hydro domain-containing protein. (365 aa)
PV08_01909Triosephosphate isomerase. (250 aa)
PV08_01884Uncharacterized protein. (119 aa)
PV08_01754T5orf172 domain-containing protein. (778 aa)
PV08_01709Amidohydro-rel domain-containing protein. (478 aa)
PV08_01498Uncharacterized protein. (335 aa)
PV08_01463ATP synthase F1, delta subunit. (224 aa)
PV08_01069Uncharacterized protein; Belongs to the 5'-nucleotidase family. (638 aa)
PV08_01019ATP synthase subunit delta, mitochondrial. (165 aa)
PV08_00374Uncharacterized protein. (127 aa)
PV08_00323Triosephosphate isomerase. (285 aa)
PV08_00197Phosphotransferase. (520 aa)
PV08_03633Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (350 aa)
PV08_02867Zn(2)-C6 fungal-type domain-containing protein. (690 aa)
PV08_02386Zn(2)-C6 fungal-type domain-containing protein. (618 aa)
PV08_02321Probable acetate kinase. (421 aa)
PV08_02301Zn(2)-C6 fungal-type domain-containing protein. (796 aa)
PV08_04969Acyl-CoA thioesterase II. (298 aa)
PV08_06497Uncharacterized protein. (2032 aa)
PV08_06050Uncharacterized protein. (798 aa)
PV08_05809Uncharacterized protein. (2293 aa)
PV08_05789Xanthine dehydrogenase. (1360 aa)
PV08_05769Acetyl-coenzyme A synthetase. (670 aa)
PV08_05718Zn(2)-C6 fungal-type domain-containing protein. (640 aa)
PV08_05324Uncharacterized protein. (366 aa)
PV08_06905Pribosyltran_N domain-containing protein. (542 aa)
PV08_01775Tr-type G domain-containing protein. (637 aa)
PV08_06760Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (509 aa)
PV08_08960ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
PV08_01983Phosphotransferase. (588 aa)
PV08_01913Uncharacterized protein. (526 aa)
PV08_01903ATP synthase subunit gamma. (297 aa)
PV08_01677Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (468 aa)
PV08_01401ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (794 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (279 aa)
PV08_01214Phosphotransferase. (495 aa)
PV08_080263-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
PV08_07986Uncharacterized protein. (273 aa)
PV08_008883-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
PV08_00485Uncharacterized protein. (58 aa)
PV08_00553Uncharacterized protein. (527 aa)
PV08_00052Uncharacterized protein. (353 aa)
PV08_09328Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (468 aa)
PV08_09288Acyl-CoA thioesterase II. (348 aa)
PV08_00191Uncharacterized protein. (390 aa)
PV08_03554Nudix hydrolase domain-containing protein. (631 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (363 aa)
PV08_03109Acyl-CoA thioesterase II. (382 aa)
PV08_033433-hydroxy-3-methylglutaryl coenzyme A reductase. (1145 aa)
PV08_02848TauD domain-containing protein. (423 aa)
PV08_02833Uncharacterized protein. (356 aa)
PV08_02713Acyl-CoA thioesterase II. (347 aa)
PV08_03037IU_nuc_hydro domain-containing protein. (437 aa)
PV08_02866Zn(2)-C6 fungal-type domain-containing protein. (620 aa)
PV08_02438Nucleoside diphosphate kinase. (153 aa)
PV08_10193Amidohydro-rel domain-containing protein. (478 aa)
PV08_02302NMT1 domain-containing protein. (310 aa)
PV08_11633Amidohydro-rel domain-containing protein. (493 aa)
PV08_02596V-type proton ATPase catalytic subunit A. (688 aa)
PV08_04749Uncharacterized protein. (329 aa)
PV08_04724Phosphoribosylglycinamide formyltransferase. (246 aa)
PV08_11281Uncharacterized protein. (156 aa)
PV08_11251Uncharacterized protein. (335 aa)
PV08_11155Uncharacterized protein. (458 aa)
PV08_044165-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase. (771 aa)
PV08_04366DOMON domain-containing protein. (479 aa)
PV08_04356Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (376 aa)
PV08_04331Fungal_trans domain-containing protein. (643 aa)
PV08_11955Uncharacterized protein. (596 aa)
PV08_11920Acyl-CoA thioesterase II. (225 aa)
PV08_04115Phosphoserine transaminase. (431 aa)
PV08_04500Phosphoribosylamine-glycine ligase. (794 aa)
PV08_04389Glucose-6-phosphate isomerase; Belongs to the GPI family. (552 aa)
PV08_03927PfkB domain-containing protein. (338 aa)
PV08_06351TauD domain-containing protein. (359 aa)
PV08_06236Pribosyltran_N domain-containing protein. (341 aa)
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
Server load: low (22%) [HD]
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