STRINGSTRING
PV08_01754 PV08_01754 PV08_12063 PV08_12063 PV08_12044 PV08_12044 PV08_10771 PV08_10771 PV08_09199 PV08_09199 PV08_09255 PV08_09255 PV08_09608 PV08_09608 BNA5 BNA5 PV08_07460 PV08_07460 PV08_07546 PV08_07546 PV08_07646 PV08_07646 PV08_07661 PV08_07661 PV08_06262 PV08_06262 PV08_06551 PV08_06551 BNA1 BNA1 PV08_04192 PV08_04192 ADK2 ADK2 PV08_03150 PV08_03150 BNA5-2 BNA5-2 PV08_01207 PV08_01207 PV08_01801 PV08_01801 PV08_01961 PV08_01961 PV08_12011 PV08_12011 PV08_11148 PV08_11148 PV08_11239 PV08_11239 PV08_10697 PV08_10697 PV08_09135 PV08_09135 PV08_09543 PV08_09543 PV08_07969 PV08_07969 PV08_08490 PV08_08490 PV08_08923 PV08_08923 PV08_06617 PV08_06617 PV08_06928 PV08_06928 PV08_06983 PV08_06983 PV08_05872 PV08_05872 PV08_06308 PV08_06308 PV08_06511 PV08_06511 PV08_02590 PV08_02590 PV08_02951 PV08_02951 PV08_02996 PV08_02996 PV08_03031 PV08_03031 PV08_00271 PV08_00271 PV08_00687 PV08_00687 PV08_00792 PV08_00792 PV08_00912 PV08_00912 PV08_01884 PV08_01884 PV08_01007 PV08_01007 PV08_01491 PV08_01491 PV08_01641 PV08_01641 PV08_01666 PV08_01666 PV08_11232 PV08_11232 PV08_11597 PV08_11597 PV08_10082 PV08_10082 PV08_09211 PV08_09211 PV08_09163 PV08_09163 PV08_09484 PV08_09484 PV08_09615 PV08_09615 PV08_09630 PV08_09630 PV08_09815 PV08_09815 PV08_08047 PV08_08047 PV08_08462 PV08_08462 PV08_08891 PV08_08891 PV08_06729 PV08_06729 PV08_06656 PV08_06656 PV08_06909 PV08_06909 PV08_06826 PV08_06826 PV08_05489 PV08_05489 PV08_05255 PV08_05255 PV08_05376 PV08_05376 PV08_05873 PV08_05873 PV08_05998 PV08_05998 PV08_06069 PV08_06069 PV08_05795 PV08_05795 PV08_05870 PV08_05870 PV08_06548 PV08_06548 PV08_06236 PV08_06236 PV08_03927 PV08_03927 PV08_04500 PV08_04500 PV08_04356 PV08_04356 PV08_04366 PV08_04366 PV08_04938 PV08_04938 PV08_11155 PV08_11155 PV08_05123 PV08_05123 PV08_04724 PV08_04724 PV08_05010 PV08_05010 PV08_02491 PV08_02491 PV08_02596 PV08_02596 PV08_02438 PV08_02438 PV08_02478 PV08_02478 PV08_02833 PV08_02833 PV08_02899 PV08_02899 PV08_02919 PV08_02919 PV08_03559 PV08_03559 PV08_09500 PV08_09500 PV08_09596 PV08_09596 PV08_00485 PV08_00485 PV08_00490 PV08_00490 PV08_00888 PV08_00888 PV08_07986 PV08_07986 PV08_00855 PV08_00855 ADK1 ADK1 BNA4 BNA4 PV08_08416 PV08_08416 PV08_01903 PV08_01903 PV08_02013 PV08_02013 PV08_02023 PV08_02023 PV08_08960 PV08_08960 PV08_06905 PV08_06905 PV08_07368 PV08_07368 PV08_05324 PV08_05324 PV08_05769 PV08_05769 PV08_05809 PV08_05809 PV08_06050 PV08_06050 PV08_06497 PV08_06497 PV08_03887 PV08_03887 PV08_04104 PV08_04104 PV08_04114 PV08_04114 PV08_02321 PV08_02321 AAH1-2 AAH1-2 PV08_03633 PV08_03633 PV08_00192 PV08_00192 PV08_00374 PV08_00374 PV08_00919 PV08_00919 PV08_01019 PV08_01019 PV08_01029 PV08_01029 PV08_01463 PV08_01463
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV08_01754T5orf172 domain-containing protein. (778 aa)
PV08_12063Uncharacterized protein. (469 aa)
PV08_12044Uncharacterized protein. (469 aa)
PV08_10771Dihydroorotase, homodimeric type. (365 aa)
PV08_09199Uncharacterized protein. (205 aa)
PV08_09255Ribonucleoside-diphosphate reductase small chain. (408 aa)
PV08_09608Uncharacterized protein. (422 aa)
BNA5Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (495 aa)
PV08_07460Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (270 aa)
PV08_07546Deoxyuridine 5'-triphosphate nucleotidohydrolase. (192 aa)
PV08_07646Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (607 aa)
PV08_07661CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (568 aa)
PV08_06262Uncharacterized protein. (227 aa)
PV08_06551Pantothenate kinase. (441 aa)
BNA13-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (184 aa)
PV08_04192Carbamoyl-phosphate synthase arginine-specific large chain. (1166 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
PV08_03150Uncharacterized protein. (203 aa)
BNA5-2Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (465 aa)
PV08_01207Amidophosphoribosyltransferase. (597 aa)
PV08_01801Isochorismatase domain-containing protein. (208 aa)
PV08_01961Dephospho-CoA kinase. (284 aa)
PV08_12011Uncharacterized protein. (475 aa)
PV08_11148Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (295 aa)
PV08_11239Uracil phosphoribosyltransferase. (248 aa)
PV08_106973-carboxy-cis,cis-muconate cycloisomerase. (450 aa)
PV08_09135Protein pyrABCN. (2297 aa)
PV08_09543Uncharacterized protein. (76 aa)
PV08_07969Uncharacterized protein. (435 aa)
PV08_08490Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. (352 aa)
PV08_08923Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
PV08_06617Formyltetrahydrofolate deformylase. (281 aa)
PV08_06928Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (305 aa)
PV08_06983Uncharacterized protein. (301 aa)
PV08_05872Pribosyltran_N domain-containing protein. (309 aa)
PV08_06308Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
PV08_06511Flavoprotein domain-containing protein. (583 aa)
PV08_02590Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (314 aa)
PV08_02951GMP synthase [glutamine-hydrolyzing]. (545 aa)
PV08_02996Phosphoribosylformylglycinamidine synthase. (1381 aa)
PV08_03031Zn(2)-C6 fungal-type domain-containing protein. (711 aa)
PV08_00271Thymidylate synthase. (387 aa)
PV08_00687Uncharacterized protein. (853 aa)
PV08_00792AMP deaminase. (1045 aa)
PV08_00912ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (556 aa)
PV08_01884Uncharacterized protein. (119 aa)
PV08_01007Uncharacterized protein. (425 aa)
PV08_01491Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (273 aa)
PV08_01641Uracil phosphoribosyltransferase. (216 aa)
PV08_01666Uridine kinase; Belongs to the uridine kinase family. (465 aa)
PV08_11232Uncharacterized protein. (697 aa)
PV08_11597Pribosyltran_N domain-containing protein. (456 aa)
PV08_10082Flavokinase domain-containing protein. (217 aa)
PV08_09211Uncharacterized protein. (485 aa)
PV08_09163PAPS_reduct domain-containing protein. (325 aa)
PV08_09484Uncharacterized protein. (465 aa)
PV08_09615Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (618 aa)
PV08_09630Uncharacterized protein. (420 aa)
PV08_09815Uncharacterized protein. (185 aa)
PV08_08047Uncharacterized protein. (120 aa)
PV08_08462Guanylate kinase. (207 aa)
PV08_08891Uncharacterized protein. (275 aa)
PV08_06729Uncharacterized protein. (656 aa)
PV08_06656ATP synthase subunit 4, mitochondrial. (244 aa)
PV08_06909Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (503 aa)
PV08_06826Uncharacterized protein. (501 aa)
PV08_05489Adenine phosphoribosyltransferase. (214 aa)
PV08_05255Isochorismatase domain-containing protein. (237 aa)
PV08_05376Uncharacterized protein. (60 aa)
PV08_05873Uracil phosphoribosyltransferase. (234 aa)
PV08_05998Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa)
PV08_06069IU_nuc_hydro domain-containing protein. (365 aa)
PV08_05795Uncharacterized protein. (410 aa)
PV08_05870Uracil phosphoribosyltransferase. (202 aa)
PV08_06548CMP/dCMP-type deaminase domain-containing protein. (312 aa)
PV08_06236Pribosyltran_N domain-containing protein. (341 aa)
PV08_03927PfkB domain-containing protein. (338 aa)
PV08_04500Phosphoribosylamine-glycine ligase. (794 aa)
PV08_04356Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (376 aa)
PV08_04366DOMON domain-containing protein. (479 aa)
PV08_04938Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (450 aa)
PV08_11155Uncharacterized protein. (458 aa)
PV08_05123Fungal_trans domain-containing protein. (617 aa)
PV08_04724Phosphoribosylglycinamide formyltransferase. (246 aa)
PV08_05010Zn(2)-C6 fungal-type domain-containing protein. (686 aa)
PV08_02491Thymidylate kinase. (230 aa)
PV08_02596V-type proton ATPase catalytic subunit A. (688 aa)
PV08_02438Nucleoside diphosphate kinase. (153 aa)
PV08_02478Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (761 aa)
PV08_02833Uncharacterized protein. (356 aa)
PV08_02899Uncharacterized protein. (338 aa)
PV08_02919Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (882 aa)
PV08_03559Isochorismatase domain-containing protein. (234 aa)
PV08_09500Flavokinase domain-containing protein. (609 aa)
PV08_09596Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (241 aa)
PV08_00485Uncharacterized protein. (58 aa)
PV08_00490Uncharacterized protein. (313 aa)
PV08_008883-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
PV08_07986Uncharacterized protein. (273 aa)
PV08_00855Dihydroorotate dehydrogenase (Fumarate). (616 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (279 aa)
BNA4Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (477 aa)
PV08_08416Flavoprotein domain-containing protein. (237 aa)
PV08_01903ATP synthase subunit gamma. (297 aa)
PV08_02013Zn(2)-C6 fungal-type domain-containing protein. (664 aa)
PV08_02023Uncharacterized protein. (512 aa)
PV08_08960ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (517 aa)
PV08_06905Pribosyltran_N domain-containing protein. (542 aa)
PV08_07368CMP/dCMP-type deaminase domain-containing protein. (412 aa)
PV08_05324Uncharacterized protein. (366 aa)
PV08_05769Acetyl-coenzyme A synthetase. (670 aa)
PV08_05809Uncharacterized protein. (2293 aa)
PV08_06050Uncharacterized protein. (798 aa)
PV08_06497Uncharacterized protein. (2032 aa)
PV08_03887Uncharacterized protein. (246 aa)
PV08_04104Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (186 aa)
PV08_04114Uncharacterized protein. (428 aa)
PV08_02321Probable acetate kinase. (421 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (350 aa)
PV08_03633Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
PV08_00192Orotate phosphoribosyltransferase. (244 aa)
PV08_00374Uncharacterized protein. (127 aa)
PV08_00919Uncharacterized protein. (394 aa)
PV08_01019ATP synthase subunit delta, mitochondrial. (165 aa)
PV08_01029Uncharacterized protein. (1037 aa)
PV08_01463ATP synthase F1, delta subunit. (224 aa)
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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