86 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_08057	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (679 aa)
	PV08_02361	Uncharacterized protein. (1359 aa)
	PV08_02993	Uncharacterized protein. (1033 aa)
	PV08_03421	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
	PV08_00258	Protein kinase domain-containing protein. (1057 aa)
	PV08_02129	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2916 aa)
	PV08_01029	Uncharacterized protein. (1037 aa)
	PV08_00696	Protein kinase domain-containing protein. (840 aa)
	PV08_00851	Uncharacterized protein. (435 aa)
	PV08_01076	Uncharacterized protein. (262 aa)
	PV08_01166	Uncharacterized protein. (649 aa)
	PV08_01490	Protein kinase domain-containing protein. (1158 aa)
	PV08_10286	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (554 aa)
	PV08_09749	Uncharacterized protein. (134 aa)
	PV08_08159	Uncharacterized protein. (420 aa)
	PV08_03870	Uncharacterized protein. (1467 aa)
	PV08_04726	Cell division control protein; Belongs to the CDC6/cdc18 family. (599 aa)
	PV08_04892	FHA domain-containing protein. (854 aa)
	PV08_02650	Uncharacterized protein. (536 aa)
	PV08_03191	Uncharacterized protein. (820 aa)
	PV08_01330	Uncharacterized protein. (274 aa)
	PV08_11154	WD_REPEATS_REGION domain-containing protein. (580 aa)
	PV08_11255	Zn(2)-C6 fungal-type domain-containing protein. (722 aa)
	PV08_10688	MRC1 domain-containing protein. (1384 aa)
	PV08_10932	Uncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (536 aa)
	PV08_09267	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (538 aa)
	PV08_09327	Fungal_trans domain-containing protein. (633 aa)
	PV08_09279	Uncharacterized protein. (876 aa)
	PV08_07924	Zn(2)-C6 fungal-type domain-containing protein. (710 aa)
	PV08_08055	Uncharacterized protein. (721 aa)
	PV08_07825	Uncharacterized protein. (77 aa)
	PV08_05860	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (328 aa)
	PV08_06286	Zds_C domain-containing protein. (916 aa)
	PV08_04113	RRM domain-containing protein. (710 aa)
	PV08_11730	Uncharacterized protein. (173 aa)
	PV08_04860	Uncharacterized protein. (683 aa)
	PV08_02335	TPR_REGION domain-containing protein. (775 aa)
	PV08_11523	ERCC4 domain-containing protein. (615 aa)
	PV08_10293	HORMA domain-containing protein. (226 aa)
	PV08_02653	Protein kinase domain-containing protein. (666 aa)
	PV08_03497	Uncharacterized protein. (530 aa)
	PV08_03422	Protein kinase domain-containing protein. (538 aa)
	PV08_09197	mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (184 aa)
	PV08_00388	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (457 aa)
	PV08_09333	Zn(2)-C6 fungal-type domain-containing protein. (550 aa)
	PV08_00092	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (474 aa)
	PV08_09505	ERCC4 domain-containing protein. (659 aa)
	PV08_00893	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (460 aa)
	PV08_09786	Uncharacterized protein. (765 aa)
	PV08_01113	Non-specific serine/threonine protein kinase. (874 aa)
	PV08_01075	Uncharacterized protein; Belongs to the protein kinase superfamily. (476 aa)
	PV08_01358	Uncharacterized protein. (851 aa)
	PV08_08727	Zn(2)-C6 fungal-type domain-containing protein. (732 aa)
	PV08_08855	ANK_REP_REGION domain-containing protein. (517 aa)
	PV08_06745	WD_REPEATS_REGION domain-containing protein. (643 aa)
	PV08_06930	TPR_REGION domain-containing protein. (770 aa)
	PV08_02150	Uncharacterized protein. (467 aa)
	PV08_07564	HORMA domain-containing protein. (440 aa)
	PV08_07826	Uncharacterized protein. (362 aa)
	PV08_08709	BRCT domain-containing protein. (1374 aa)
	PV08_06636	Rab-GAP TBC domain-containing protein. (443 aa)
	PV08_07158	TYR_PHOSPHATASE_2 domain-containing protein. (646 aa)
	PV08_07666	Uncharacterized protein. (806 aa)
	PV08_07686	Rhodanese domain-containing protein. (561 aa)
	PV08_05547	Uncharacterized protein. (1399 aa)
	PV08_05911	Uncharacterized protein. (519 aa)
	PV08_06282	DBF4-type domain-containing protein. (631 aa)
	PV08_06478	Non-specific serine/threonine protein kinase. (872 aa)
	PV08_04187	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
	PV08_04292	Uncharacterized protein. (179 aa)
	PV08_04695	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (414 aa)
	PV08_04761	Spc7 domain-containing protein. (1727 aa)
	PV08_03235	Zn(2)-C6 fungal-type domain-containing protein. (649 aa)
	PV08_03454	WD_REPEATS_REGION domain-containing protein. (611 aa)
	PV08_08028	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (768 aa)
	PV08_09879	PARP-type domain-containing protein. (291 aa)
	PV08_09457	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
	PV08_09068	WD_REPEATS_REGION domain-containing protein. (350 aa)
	PV08_10225	Protein kinase domain-containing protein. (574 aa)
	PV08_10090	Cell division control protein 42. (245 aa)
	PV08_11635	Zn(2)-C6 fungal-type domain-containing protein. (651 aa)
	PV08_05713	Uncharacterized protein. (912 aa)
	PV08_05999	Serine/threonine-protein kinase pef1; Belongs to the protein kinase superfamily. (338 aa)
	PV08_06100	Uncharacterized protein. (621 aa)
	PV08_03949	Uncharacterized protein. (115 aa)
	PV08_04405	Checkpoint protein; Belongs to the HUS1 family. (348 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00092	PV08_00258	A0A0D2BLU8	A0A0D2C7X5	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Protein kinase domain-containing protein.	0.967
PV08_00092	PV08_01029	A0A0D2BLU8	A0A0D2CA72	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Uncharacterized protein.	0.947
PV08_00092	PV08_01490	A0A0D2BLU8	A0A0D1Z021	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Protein kinase domain-containing protein.	0.967
PV08_00092	PV08_02361	A0A0D2BLU8	A0A0D2C399	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Uncharacterized protein.	0.735
PV08_00092	PV08_03422	A0A0D2BLU8	A0A0D2BKM5	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Protein kinase domain-containing protein.	0.950
PV08_00092	PV08_03454	A0A0D2BLU8	A0A0D1YV46	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	WD_REPEATS_REGION domain-containing protein.	0.658
PV08_00092	PV08_03497	A0A0D2BLU8	A0A0D2BJV6	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Uncharacterized protein.	0.566
PV08_00092	PV08_04187	A0A0D2BLU8	A0A0D1YPB4	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.896
PV08_00092	PV08_04695	A0A0D2BLU8	A0A0D1YQL9	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.769
PV08_00092	PV08_04860	A0A0D2BLU8	A0A0D2BGA7	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Uncharacterized protein.	0.735
PV08_00092	PV08_05860	A0A0D2BLU8	A0A0D2BB20	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.916
PV08_00092	PV08_05999	A0A0D2BLU8	A0A0D2BXE1	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine/threonine-protein kinase pef1; Belongs to the protein kinase superfamily.	0.916
PV08_00092	PV08_06100	A0A0D2BLU8	A0A0D2BXR6	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Uncharacterized protein.	0.999
PV08_00092	PV08_06286	A0A0D2BLU8	A0A0D2BC81	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Zds_C domain-containing protein.	0.807
PV08_00092	PV08_06636	A0A0D2BLU8	A0A0D1YFL4	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Rab-GAP TBC domain-containing protein.	0.949
PV08_00092	PV08_06745	A0A0D2BLU8	A0A0D2BRX2	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	WD_REPEATS_REGION domain-containing protein.	0.658
PV08_00092	PV08_07158	A0A0D2BLU8	A0A0D1YHG9	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	TYR_PHOSPHATASE_2 domain-containing protein.	0.626
PV08_00092	PV08_07686	A0A0D2BLU8	A0A0D1YIY6	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Rhodanese domain-containing protein.	0.602
PV08_00092	PV08_08057	A0A0D2BLU8	A0A0D2B2M8	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.	0.964
PV08_00092	PV08_09197	A0A0D2BLU8	A0A0D2BL19	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.	0.907