81 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_00622	Uncharacterized protein. (710 aa)
	PV08_06043	RRM domain-containing protein. (282 aa)
	PV08_04037	18S rRNA biogenesis protein RCL1. (406 aa)
	PV08_04238	WD_REPEATS_REGION domain-containing protein. (960 aa)
	PV08_04388	Uncharacterized protein. (1030 aa)
	PV08_04977	40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (261 aa)
	PV08_02926	F-box domain-containing protein. (1204 aa)
	PV08_11366	RRM domain-containing protein. (660 aa)
	PV08_11378	Zn(2)-C6 fungal-type domain-containing protein. (745 aa)
	PV08_11404	WD_REPEATS_REGION domain-containing protein. (443 aa)
	PV08_10262	Uncharacterized protein. (713 aa)
	PV08_10119	Uncharacterized protein. (597 aa)
	PV08_10124	DRIM domain-containing protein. (2590 aa)
	PV08_11002	WD_REPEATS_REGION domain-containing protein. (984 aa)
	PV08_09342	Brix domain-containing protein. (343 aa)
	PV08_09454	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (335 aa)
	PV08_09595	Uncharacterized protein. (504 aa)
	PV08_09314	RING-type domain-containing protein. (701 aa)
	PV08_08244	TRASH domain-containing protein. (213 aa)
	PV08_09165	RNA helicase. (878 aa)
	PV08_10838	C2H2-type domain-containing protein. (113 aa)
	PV08_11380	RNA helicase. (639 aa)
	PV08_11743	Zn(2)-C6 fungal-type domain-containing protein. (710 aa)
	PV08_01901	S4 RNA-binding domain-containing protein. (188 aa)
	PV08_00536	RRM domain-containing protein. (488 aa)
	PV08_03575	Uncharacterized protein. (823 aa)
	PV08_03275	Uncharacterized protein. (703 aa)
	PV08_03155	Uncharacterized protein. (296 aa)
	PV08_02348	Uncharacterized protein. (272 aa)
	PV08_04926	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (221 aa)
	PV08_04670	WD_REPEATS_REGION domain-containing protein. (588 aa)
	PV08_04467	Protein MAK16; Belongs to the MAK16 family. (327 aa)
	PV08_04136	Uncharacterized protein. (900 aa)
	PV08_03935	Uncharacterized protein. (471 aa)
	PV08_09906	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (290 aa)
	PV08_09931	Sas10 domain-containing protein. (605 aa)
	PV08_08591	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (743 aa)
	PV08_08317	Uncharacterized protein. (262 aa)
	PV08_08859	CBF domain-containing protein. (1043 aa)
	PV08_08869	Uncharacterized protein. (306 aa)
	PV08_06744	Utp12 domain-containing protein. (934 aa)
	PV08_06741	Bms1-type G domain-containing protein. (811 aa)
	PV08_07362	NUC153 domain-containing protein. (717 aa)
	PV08_05288	Uncharacterized protein. (335 aa)
	PV08_05658	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (188 aa)
	PV08_06189	Uncharacterized protein; Belongs to the DEAD box helicase family. (514 aa)
	PV08_06256	Uncharacterized protein. (231 aa)
	PV08_03828	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (765 aa)
	PV08_04510	Uncharacterized protein. (306 aa)
	PV08_04617	Uncharacterized protein. (189 aa)
	PV08_10734	RNA helicase. (627 aa)
	PV08_06556	Uncharacterized protein; Belongs to the DEAD box helicase family. (529 aa)
	PV08_07425	Ribosome biogenesis protein nsa2. (261 aa)
	PV08_06657	CBF domain-containing protein. (287 aa)
	PV08_09537	Uncharacterized protein. (355 aa)
	PV08_11379	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (437 aa)
	PV08_03084	Uncharacterized protein. (710 aa)
	PV08_01683	Uncharacterized protein. (884 aa)
	PV08_00879	Uncharacterized protein. (513 aa)
	PV08_00719	Brix domain-containing protein. (382 aa)
	PV08_04914	PINc domain-containing protein. (194 aa)
	PV08_04506	Uncharacterized protein. (195 aa)
	PV08_04094	AB hydrolase-1 domain-containing protein. (380 aa)
	PV08_06549	Uncharacterized protein. (253 aa)
	PV08_05657	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (685 aa)
	PV08_07766	U3 small nucleolar RNA-associated protein 22. (1121 aa)
	PV08_07318	WD_REPEATS_REGION domain-containing protein. (603 aa)
	PV08_07273	WD_REPEATS_REGION domain-containing protein. (557 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (830 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1129 aa)
	PV08_01815	RIO domain-containing protein. (382 aa)
	PV08_01564	Uncharacterized protein. (1823 aa)
	PV08_01973	ATP-dependent RNA helicase DBP10. (911 aa)
	PV08_08617	Brix domain-containing protein. (296 aa)
	PV08_01257	Uncharacterized protein. (1242 aa)
	PV08_08176	Zn(2)-C6 fungal-type domain-containing protein. (738 aa)
	PV08_00940	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (146 aa)
	PV08_00630	Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (518 aa)
	PV08_10941	Uncharacterized protein. (388 aa)
	PV08_06893	Uncharacterized protein. (938 aa)
	PV08_07597	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (315 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NAT10	PV08_00536	A0A0D2BS61	A0A0D1YXH0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	RRM domain-containing protein.	0.807
NAT10	PV08_00630	A0A0D2BS61	A0A0D2BNF2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family.	0.664
NAT10	PV08_00719	A0A0D2BS61	A0A0D2C992	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Brix domain-containing protein.	0.882
NAT10	PV08_00879	A0A0D2BS61	A0A0D2C9P3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.997
NAT10	PV08_00940	A0A0D2BS61	A0A0D2BPC1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	40S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.948
NAT10	PV08_01257	A0A0D2BS61	A0A0D2BQA9	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.963
NAT10	PV08_01564	A0A0D2BS61	A0A0D2BRE7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.992
NAT10	PV08_01683	A0A0D2BS61	A0A0D2CC96	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.631
NAT10	PV08_01815	A0A0D2BS61	A0A0D2BS26	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	RIO domain-containing protein.	0.693
NAT10	PV08_01901	A0A0D2BS61	A0A0D1Z0Z2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	S4 RNA-binding domain-containing protein.	0.952
NAT10	PV08_01973	A0A0D2BS61	A0A0D2BQW1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	ATP-dependent RNA helicase DBP10.	0.866
NAT10	PV08_02348	A0A0D2BS61	A0A0D1YS63	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.511
NAT10	PV08_03084	A0A0D2BS61	A0A0D2BJL7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.911
NAT10	PV08_03155	A0A0D2BS61	A0A0D1YUD5	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.991
NAT10	PV08_03275	A0A0D2BS61	A0A0D1YUR0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.861
NAT10	PV08_03575	A0A0D2BS61	A0A0D1YVF5	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.612
NAT10	PV08_03828	A0A0D2BS61	A0A0D2BDE9	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.	0.745
NAT10	PV08_03935	A0A0D2BS61	A0A0D1YNQ8	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.721
NAT10	PV08_04037	A0A0D2BS61	A0A0D1ZVW7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	18S rRNA biogenesis protein RCL1.	0.985
NAT10	PV08_04094	A0A0D2BS61	A0A0D2BZX6	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	AB hydrolase-1 domain-containing protein.	0.473