146 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_09050	WD_REPEATS_REGION domain-containing protein. (549 aa)
	PV08_02114	WD_REPEATS_REGION domain-containing protein. (185 aa)
	PV08_01144	EMC1_C domain-containing protein. (961 aa)
	PV08_01139	Uncharacterized protein. (801 aa)
	PV08_01114	Uncharacterized protein. (646 aa)
	PV08_00243	WD_REPEATS_REGION domain-containing protein. (506 aa)
	PV08_02597	Uncharacterized protein. (624 aa)
	PV08_02442	WD_REPEATS_REGION domain-containing protein. (413 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (459 aa)
	PV08_04989	PPIase cyclophilin-type domain-containing protein. (617 aa)
	PV08_04904	WD_REPEATS_REGION domain-containing protein. (526 aa)
	PV08_04779	WD_REPEATS_REGION domain-containing protein. (726 aa)
	PV08_04758	WD_REPEATS_REGION domain-containing protein. (1200 aa)
	PV08_04300	Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. (1510 aa)
	PV08_04124	Uncharacterized protein. (393 aa)
	PV08_03913	WD_REPEATS_REGION domain-containing protein. (338 aa)
	PV08_06009	Uncharacterized protein. (679 aa)
	PV08_05739	WD_REPEATS_REGION domain-containing protein. (671 aa)
	PV08_05289	Zinc_ribbon_16 domain-containing protein. (1082 aa)
	PV08_07428	WD_REPEATS_REGION domain-containing protein. (537 aa)
	PV08_07318	WD_REPEATS_REGION domain-containing protein. (603 aa)
	PV08_07273	WD_REPEATS_REGION domain-containing protein. (557 aa)
	PV08_07263	Uncharacterized protein. (942 aa)
	PV08_01805	Pre-mRNA-splicing factor prp46. (463 aa)
	PV08_06745	WD_REPEATS_REGION domain-containing protein. (643 aa)
	PV08_02148	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (830 aa)
	PV08_08773	WD_REPEATS_REGION domain-containing protein. (840 aa)
	PV08_01918	WD_REPEATS_REGION domain-containing protein. (1052 aa)
	PV08_01383	Uncharacterized protein. (451 aa)
	PV08_01883	WD_REPEATS_REGION domain-containing protein. (685 aa)
	PV08_08171	WD_REPEATS_REGION domain-containing protein. (533 aa)
	PV08_00710	LisH domain-containing protein. (483 aa)
	PV08_00645	WSC domain-containing protein. (1091 aa)
	PV08_09761	Rav1p_C domain-containing protein. (1314 aa)
	PV08_09444	WD_REPEATS_REGION domain-containing protein. (1135 aa)
	PV08_00092	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (474 aa)
	PV08_09238	Uncharacterized protein. (915 aa)
	PV08_09172	Uncharacterized protein. (412 aa)
	PV08_11006	Pre-mRNA-splicing factor rse1. (1208 aa)
	PV08_03522	WD_REPEATS_REGION domain-containing protein. (1434 aa)
	PV08_03456	WD_REPEATS_REGION domain-containing protein. (362 aa)
	PV08_03303	WD_REPEATS_REGION domain-containing protein. (476 aa)
	PV08_02954	WD_REPEATS_REGION domain-containing protein. (680 aa)
	PV08_10709	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1180 aa)
	PV08_10539	Uncharacterized protein. (415 aa)
	PV08_10218	WD_REPEATS_REGION domain-containing protein. (782 aa)
	PV08_02392	IPPc domain-containing protein. (1257 aa)
	PV08_02621	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (461 aa)
	PV08_02481	WD_REPEATS_REGION domain-containing protein. (864 aa)
	PV08_04820	Uncharacterized protein. (1186 aa)
	PV08_04963	WD_REPEATS_REGION domain-containing protein. (1302 aa)
	PV08_04231	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (536 aa)
	PRT1	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (743 aa)
	PV08_03932	WD_REPEATS_REGION domain-containing protein. (1541 aa)
	PV08_06376	Uncharacterized protein. (409 aa)
	PV08_05775	Coronin; Belongs to the WD repeat coronin family. (588 aa)
	PV08_05740	WD_REPEATS_REGION domain-containing protein. (519 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (457 aa)
	PV08_05531	WD_REPEATS_REGION domain-containing protein. (365 aa)
	PV08_05340	Uncharacterized protein. (712 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (781 aa)
	TRM82	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (557 aa)
	PV08_07563	Uncharacterized protein. (1082 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1201 aa)
	PV08_07362	NUC153 domain-containing protein. (717 aa)
	PV08_06891	Uncharacterized protein. (394 aa)
	PV08_06744	Utp12 domain-containing protein. (934 aa)
	PV08_08936	WD_REPEATS_REGION domain-containing protein. (335 aa)
	PV08_08581	WD_REPEATS_REGION domain-containing protein. (347 aa)
	PV08_08355	Uncharacterized protein. (1663 aa)
	CIA1	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (558 aa)
	PV08_08025	CPSF_A domain-containing protein. (1205 aa)
	PV08_09697	WD_REPEATS_REGION domain-containing protein. (588 aa)
	PV08_09835	WD_REPEATS_REGION domain-containing protein. (339 aa)
	PV08_09595	Uncharacterized protein. (504 aa)
	PV08_09549	Uncharacterized protein. (1686 aa)
	PV08_09257	WD_REPEATS_REGION domain-containing protein. (354 aa)
	PV08_11007	Uncharacterized protein. (482 aa)
	PV08_11002	WD_REPEATS_REGION domain-containing protein. (984 aa)
	PV08_09086	WD_REPEATS_REGION domain-containing protein. (401 aa)
	PV08_10755	Uncharacterized protein. (1267 aa)
	PV08_10658	WD_REPEATS_REGION domain-containing protein. (349 aa)
	PV08_10513	WD_REPEATS_REGION domain-containing protein. (1000 aa)
	PV08_10077	Guanine nucleotide-binding protein subunit beta-like protein. (316 aa)
	PV08_11404	WD_REPEATS_REGION domain-containing protein. (443 aa)
	PV08_11647	Uncharacterized protein. (360 aa)
	PV08_11202	WD_REPEATS_REGION domain-containing protein. (809 aa)
	PV08_11154	WD_REPEATS_REGION domain-containing protein. (580 aa)
	PV08_11941	Uncharacterized protein. (1346 aa)
	PV08_11926	Ribosomal protein L32. (417 aa)
	PV08_01847	Vps8 domain-containing protein. (1590 aa)
	PV08_01405	WD_REPEATS_REGION domain-containing protein. (990 aa)
	PV08_01197	Uncharacterized protein. (2558 aa)
	PV08_01112	Uncharacterized protein. (482 aa)
	PV08_00099	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (843 aa)
	PV08_03191	Uncharacterized protein. (820 aa)
	PV08_02926	F-box domain-containing protein. (1204 aa)
	PV08_02595	Uncharacterized protein. (630 aa)
	PV08_02460	Uncharacterized protein. (768 aa)
	PV08_05002	WD_REPEATS_REGION domain-containing protein. (508 aa)
	PV08_04666	WD_REPEATS_REGION domain-containing protein. (963 aa)
	PV08_04388	Uncharacterized protein. (1030 aa)
	PV08_04238	WD_REPEATS_REGION domain-containing protein. (960 aa)
	PV08_04228	CPSF_A domain-containing protein. (1359 aa)
	PV08_06393	F-box domain-containing protein. (602 aa)
	PV08_06168	NUP214 domain-containing protein. (1507 aa)
	PV08_06133	WD_REPEATS_REGION domain-containing protein. (1505 aa)
	PV08_05887	Uncharacterized protein. (950 aa)
	PV08_05615	Uncharacterized protein. (1294 aa)
	PV08_07652	Uncharacterized protein. (678 aa)
	PV08_07195	WD_REPEATS_REGION domain-containing protein. (611 aa)
	PV08_06627	Uncharacterized protein. (1133 aa)
	PV08_06612	WD_REPEATS_REGION domain-containing protein. (626 aa)
	PV08_08933	WD_REPEATS_REGION domain-containing protein. (436 aa)
	PV08_08530	Uncharacterized protein. (457 aa)
	PV08_08174	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1043 aa)
	PV08_09629	Uncharacterized protein. (697 aa)
	PV08_11466	Uncharacterized protein. (413 aa)
	PV08_11209	WD_REPEATS_REGION domain-containing protein. (624 aa)
	PV08_11963	RIC1 domain-containing protein. (1049 aa)
	PV08_01951	Uncharacterized protein. (827 aa)
	PV08_01565	Uncharacterized protein. (669 aa)
	PV08_01560	WD_REPEATS_REGION domain-containing protein. (470 aa)
	PV08_01191	WD_REPEATS_REGION domain-containing protein. (657 aa)
	PV08_00496	WD_REPEATS_REGION domain-containing protein. (567 aa)
	PV08_03454	WD_REPEATS_REGION domain-containing protein. (611 aa)
	PV08_03351	WD_REPEATS_REGION domain-containing protein. (1350 aa)
	PV08_02945	Uncharacterized protein. (356 aa)
	PV08_04906	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	PV08_04670	WD_REPEATS_REGION domain-containing protein. (588 aa)
	PV08_04262	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (357 aa)
	PV08_03925	Uncharacterized protein. (1466 aa)
	PV08_06232	Uncharacterized protein. (686 aa)
	PV08_05397	WD_REPEATS_REGION domain-containing protein. (705 aa)
	PV08_07878	WD_REPEATS_REGION domain-containing protein. (533 aa)
	PV08_07848	eIF2A domain-containing protein. (749 aa)
	PV08_07696	WD_REPEATS_REGION domain-containing protein. (492 aa)
	PV08_06832	WD_REPEATS_REGION domain-containing protein. (1265 aa)
	PV08_06652	DUF2415 domain-containing protein. (933 aa)
	PV08_09517	WD_REPEATS_REGION domain-containing protein. (508 aa)
	PV08_09345	Uncharacterized protein. (800 aa)
	PV08_09340	E3 ubiquitin-protein ligase PEP5. (981 aa)
	PV08_09270	Guanine nucleotide-binding protein subunit beta. (351 aa)
	PV08_09124	Uncharacterized protein. (1669 aa)
	PV08_09068	WD_REPEATS_REGION domain-containing protein. (350 aa)
	TIF34	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (336 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERB1	PRT1	A0A0D2B947	A0A0D2BEI7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	0.708
ERB1	PV08_01112	A0A0D2B947	A0A0D2A715	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.613
ERB1	PV08_01383	A0A0D2B947	A0A0D2BQQ4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.628
ERB1	PV08_01405	A0A0D2B947	A0A0D2A7R1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.791
ERB1	PV08_02460	A0A0D2B947	A0A0D1ZZM4	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.732
ERB1	PV08_02481	A0A0D2B947	A0A0D2BGR1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.909
ERB1	PV08_03454	A0A0D2B947	A0A0D1YV46	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.732
ERB1	PV08_04238	A0A0D2B947	A0A0D1ZWJ9	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.921
ERB1	PV08_04388	A0A0D2B947	A0A0D1ZWX3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.910
ERB1	PV08_04666	A0A0D2B947	A0A0D1ZXW9	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.897
ERB1	PV08_04670	A0A0D2B947	A0A0D1YQH6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.811
ERB1	PV08_04904	A0A0D2B947	A0A0D2C226	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.909
ERB1	PV08_05739	A0A0D2B947	A0A0D2BWM5	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.732
ERB1	PV08_06133	A0A0D2B947	A0A0D1ZTI1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.858
ERB1	PV08_06232	A0A0D2B947	A0A0D1YMD2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.732
ERB1	PV08_06744	A0A0D2B947	A0A0D2B4Y7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Utp12 domain-containing protein.	0.792
ERB1	PV08_06745	A0A0D2B947	A0A0D2BRX2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.732
ERB1	PV08_07195	A0A0D2B947	A0A0D1ZNJ7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.732
ERB1	PV08_07273	A0A0D2B947	A0A0D2BTD2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.905
ERB1	PV08_07318	A0A0D2B947	A0A0D2BTI7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.940