81 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_06105	Uncharacterized protein. (595 aa)
	PV08_05789	Xanthine dehydrogenase. (1360 aa)
	PV08_05632	Uncharacterized protein. (663 aa)
	PV08_05425	FAD-binding FR-type domain-containing protein. (312 aa)
	PV08_07881	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family. (1055 aa)
	PV08_07418	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. (881 aa)
	PV08_08702	Uncharacterized protein. (454 aa)
	PV08_08547	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (592 aa)
	PV08_01155	Uncharacterized protein. (585 aa)
	PV08_01557	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (589 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (477 aa)
	PV08_01013	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (615 aa)
	PV08_00843	GMC_OxRdtase_N domain-containing protein. (638 aa)
	PV08_00838	Fumarate reductase; Irreversibly catalyzes the reduction of fumarate to succinate. (469 aa)
	PV08_00037	Uncharacterized protein. (400 aa)
	PV08_00186	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (643 aa)
	PV08_00015	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (469 aa)
	PV08_03507	Uncharacterized protein. (435 aa)
	PV08_03207	GMC_OxRdtase_N domain-containing protein. (667 aa)
	PV08_10599	DAO domain-containing protein. (362 aa)
	PV08_02568	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (661 aa)
	PV08_10018	Amine oxidase. (625 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (533 aa)
	PV08_04818	GMC_OxRdtase_N domain-containing protein. (697 aa)
	PV08_04159	Uncharacterized protein. (422 aa)
	TAH18	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (645 aa)
	PV08_03902	Uncharacterized protein. (500 aa)
	PV08_05564	DAO domain-containing protein. (353 aa)
	PV08_07872	Sulfhydryl oxidase. (186 aa)
	PV08_07717	Uncharacterized protein. (445 aa)
	PV08_07543	Uncharacterized protein. (456 aa)
	PV08_07229	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (670 aa)
	PV08_07125	Uncharacterized protein. (568 aa)
	PV08_08370	Uncharacterized protein. (443 aa)
	cprA	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (691 aa)
	PV08_11659	Amine oxidase. (253 aa)
	PV08_11799	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (287 aa)
	PV08_01007	Uncharacterized protein. (425 aa)
	PV08_00029	Uncharacterized protein. (424 aa)
	PV08_02535	Uncharacterized protein. (549 aa)
	PV08_02530	Amine oxidase. (600 aa)
	PV08_05067	Sulfhydryl oxidase. (219 aa)
	PV08_04168	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (709 aa)
	PV08_03901	FAD-binding FR-type domain-containing protein. (426 aa)
	PV08_05610	NADPH:adrenodoxin oxidoreductase, mitochondrial. (527 aa)
	PV08_05302	Uncharacterized protein. (471 aa)
	PV08_11762	Uncharacterized protein. (566 aa)
	PV08_07431	GMC_OxRdtase_N domain-containing protein. (555 aa)
	PV08_07421	Uncharacterized protein. (578 aa)
	PV08_08984	Amine oxidase. (494 aa)
	PV08_08334	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (699 aa)
	PV08_09890	Amine oxidase. (442 aa)
	PV08_10181	Dihydrolipoyl dehydrogenase. (516 aa)
	PV08_11626	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (631 aa)
	PV08_11596	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (501 aa)
	PV08_11683	DAO domain-containing protein. (400 aa)
	PV08_01273	Uncharacterized protein. (460 aa)
	PV08_00866	Amine oxidase. (604 aa)
	PV08_03368	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (502 aa)
	PV08_02644	Uncharacterized protein. (473 aa)
	PV08_02494	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (738 aa)
	PV08_04472	Amine oxidase. (471 aa)
	PV08_04412	Uncharacterized protein. (432 aa)
	PV08_04096	GMC_OxRdtase_N domain-containing protein. (580 aa)
	PV08_06357	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (703 aa)
	PV08_05437	Xanthine dehydrogenase, molybdopterin binding subunit. (1485 aa)
	PV08_05196	Thioredoxin reductase. (358 aa)
	PV08_07908	FAD-binding PCMH-type domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (479 aa)
	PV08_08684	Uncharacterized protein. (623 aa)
	PV08_11797	Amine oxidase. (495 aa)
	PV08_11273	DAO domain-containing protein. (349 aa)
	PV08_10511	Amine oxidase. (449 aa)
	PV08_10671	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (336 aa)
	PV08_09335	Uncharacterized protein. (634 aa)
	PV08_09608	Uncharacterized protein. (422 aa)
	PV08_08494	Uncharacterized protein. (584 aa)
	PV08_01959	Uncharacterized protein. (433 aa)
	PV08_03228	DAO domain-containing protein. (333 aa)
	PV08_02933	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (477 aa)
	PV08_02452	Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family. (1057 aa)
	PV08_06330	Uncharacterized protein. (449 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA4	PV08_07418	A0A0D2BP93	A0A0D2BTR4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.476
COQ6	PV08_05610	A0A0D2BG28	A0A0D1ZS11	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	NADPH:adrenodoxin oxidoreductase, mitochondrial.	0.426
PV08_00029	PV08_07418	A0A0D2A3J6	A0A0D2BTR4	Uncharacterized protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.693
PV08_00037	PV08_01007	A0A0D2BLM7	A0A0D2A6P2	Uncharacterized protein.	Uncharacterized protein.	0.762
PV08_00037	PV08_01273	A0A0D2BLM7	A0A0D1YZF7	Uncharacterized protein.	Uncharacterized protein.	0.689
PV08_00037	PV08_02644	A0A0D2BLM7	A0A0D1YSU7	Uncharacterized protein.	Uncharacterized protein.	0.427
PV08_00037	PV08_02933	A0A0D2BLM7	A0A0D2C4X8	Uncharacterized protein.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.427
PV08_00037	PV08_03507	A0A0D2BLM7	A0A0D2BJW6	Uncharacterized protein.	Uncharacterized protein.	0.683
PV08_00037	PV08_03902	A0A0D2BLM7	A0A0D2BCK7	Uncharacterized protein.	Uncharacterized protein.	0.449
PV08_00037	PV08_04168	A0A0D2BLM7	A0A0D1ZWD4	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.620
PV08_00037	PV08_04412	A0A0D2BLM7	A0A0D1YPS5	Uncharacterized protein.	Uncharacterized protein.	0.756
PV08_00037	PV08_05302	A0A0D2BLM7	A0A0D1ZR13	Uncharacterized protein.	Uncharacterized protein.	0.772
PV08_00037	PV08_05632	A0A0D2BLM7	A0A0D2BWF2	Uncharacterized protein.	Uncharacterized protein.	0.441
PV08_00037	PV08_06330	A0A0D2BLM7	A0A0D2BY87	Uncharacterized protein.	Uncharacterized protein.	0.471
PV08_00037	PV08_06357	A0A0D2BLM7	A0A0D1YMN3	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.620
PV08_00037	PV08_07418	A0A0D2BLM7	A0A0D2BTR4	Uncharacterized protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.765
PV08_00037	PV08_07543	A0A0D2BLM7	A0A0D2B746	Uncharacterized protein.	Uncharacterized protein.	0.671
PV08_00037	PV08_07717	A0A0D2BLM7	A0A0D2B8D9	Uncharacterized protein.	Uncharacterized protein.	0.655
PV08_00037	PV08_08334	A0A0D2BLM7	A0A0D1ZJZ7	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.620
PV08_00037	PV08_08702	A0A0D2BLM7	A0A0D2BQV2	Uncharacterized protein.	Uncharacterized protein.	0.597