STRINGSTRING
PV08_07634 PV08_07634 PV08_05324 PV08_05324 PV08_05754 PV08_05754 PV08_05809 PV08_05809 PV08_05939 PV08_05939 PV08_06120 PV08_06120 PV08_03767 PV08_03767 PV08_04355 PV08_04355 PV08_04415 PV08_04415 PV08_04964 PV08_04964 PV08_02306 PV08_02306 PV08_02477 PV08_02477 PV08_02562 PV08_02562 PV08_02637 PV08_02637 PV08_03183 PV08_03183 PV08_00011 PV08_00011 PV08_00514 PV08_00514 PV08_00774 PV08_00774 PV08_00909 PV08_00909 PV08_01004 PV08_01004 PV08_01069 PV08_01069 PV08_11780 PV08_11780 PV08_04938 PV08_04938 PV08_04634 PV08_04634 PV08_11211 PV08_11211 COQ6 COQ6 PV08_04935 PV08_04935 PV08_02696 PV08_02696 PV08_02413 PV08_02413 PV08_02478 PV08_02478 PV08_02563 PV08_02563 PV08_02881 PV08_02881 PV08_02573 PV08_02573 PV08_02603 PV08_02603 PV08_02698 PV08_02698 PV08_03182 PV08_03182 PV08_10784 PV08_10784 PV08_10951 PV08_10951 PV08_09056 PV08_09056 PV08_00141 PV08_00141 PV08_00186 PV08_00186 PV08_09079 PV08_09079 PV08_10552 PV08_10552 PV08_10366 PV08_10366 PV08_10096 PV08_10096 COQ7 COQ7 PV08_10807 PV08_10807 PV08_11013 PV08_11013 PV08_08293 PV08_08293 PV08_08749 PV08_08749 PV08_08877 PV08_08877 PV08_02126 PV08_02126 PV08_01961 PV08_01961 PV08_01931 PV08_01931 PV08_01141 PV08_01141 PV08_01056 PV08_01056 PV08_03297 PV08_03297 PV08_03146 PV08_03146 PV08_02590 PV08_02590 hxB hxB PV08_04736 PV08_04736 PV08_04676 PV08_04676 PV08_04408 PV08_04408 PV08_06428 PV08_06428 PV08_07807 PV08_07807 PV08_06328 PV08_06328 PV08_05508 PV08_05508 cnxH cnxH PV08_07784 PV08_07784 PV08_07210 PV08_07210 PV08_08700 PV08_08700 PV08_08690 PV08_08690 PV08_08134 PV08_08134 PV08_07882 PV08_07882 PV08_05449 PV08_05449 PV08_05381 PV08_05381 PV08_05795 PV08_05795 PV08_05905 PV08_05905 PV08_00466 PV08_00466 PV08_05995 PV08_05995 PV08_09990 PV08_09990 PV08_09609 PV08_09609 PV08_09493 PV08_09493 PV08_09488 PV08_09488 PV08_03971 PV08_03971 PV08_03874 PV08_03874 PV08_03769 PV08_03769 PV08_06551 PV08_06551 PV08_05442 PV08_05442 PV08_07460 PV08_07460 PV08_06015 PV08_06015 PV08_06480 PV08_06480 PV08_06331 PV08_06331 PV08_03993 PV08_03993 PV08_04028 PV08_04028 PV08_06540 PV08_06540 PV08_03919 PV08_03919 PV08_04229 PV08_04229 PV08_11975 PV08_11975 PV08_05343 PV08_05343 PV08_05308 PV08_05308 PV08_05213 PV08_05213 PV08_07655 PV08_07655 PV08_07545 PV08_07545 PV08_07449 PV08_07449 COQ5 COQ5 PV08_07442 PV08_07442 PV08_06729 PV08_06729 PV08_06689 PV08_06689 PV08_08748 PV08_08748 PV08_08468 PV08_08468 PV08_08641 PV08_08641 PV08_08407 PV08_08407 PV08_08576 PV08_08576 PV08_08415 PV08_08415 PV08_08072 PV08_08072 PV08_08335 PV08_08335 PV08_08007 PV08_08007 PV08_07997 PV08_07997 PV08_07967 PV08_07967 PV08_08050 PV08_08050 PV08_09991 PV08_09991 PV08_09662 PV08_09662 PV08_09815 PV08_09815 PV08_09715 PV08_09715 PV08_09630 PV08_09630 cprA cprA PV08_09163 PV08_09163 PV08_09161 PV08_09161 PV08_10814 PV08_10814 PV08_10545 PV08_10545 PV08_00154 PV08_00154 PV08_03060 PV08_03060 PV08_03050 PV08_03050 PV08_02920 PV08_02920 PV08_02679 PV08_02679 PV08_02494 PV08_02494 PV08_02479 PV08_02479 PV08_02303 PV08_02303 PV08_10753 PV08_10753 PV08_10309 PV08_10309 PV08_11664 PV08_11664 PV08_11449 PV08_11449 PV08_10082 PV08_10082 PV08_11632 PV08_11632 PV08_11287 PV08_11287 PV08_11282 PV08_11282 PV08_11295 PV08_11295 PV08_11230 PV08_11230 PV08_11724 PV08_11724 PV08_11924 PV08_11924 PV08_02102 PV08_02102 PV08_01107 PV08_01107 COQ3 COQ3 PV08_03677 PV08_03677 PV08_02264 PV08_02264 PV08_02124 PV08_02124 PV08_01754 PV08_01754 PV08_01498 PV08_01498 PV08_01109 PV08_01109 PV08_00282 PV08_00282 PV08_09500 PV08_09500 PV08_00618 PV08_00618 PV08_09601 PV08_09601 PV08_00638 PV08_00638 PV08_00360 PV08_00360 PV08_00490 PV08_00490 PV08_01058 PV08_01058 PV08_01063 PV08_01063 PV08_00745 PV08_00745 PV08_01204 PV08_01204 PV08_01170 PV08_01170 PV08_08492 PV08_08492 PV08_01353 PV08_01353 PV08_08788 PV08_08788 PV08_02023 PV08_02023 PV08_06740 PV08_06740
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV08_07634FAD_binding_3 domain-containing protein. (618 aa)
PV08_05324Uncharacterized protein. (366 aa)
PV08_05754Uncharacterized protein. (145 aa)
PV08_05809Uncharacterized protein. (2293 aa)
PV08_05939Aldedh domain-containing protein. (492 aa)
PV08_06120FAD_binding_3 domain-containing protein. (438 aa)
PV08_03767Uncharacterized protein. (566 aa)
PV08_04355Metallophos domain-containing protein. (602 aa)
PV08_04415Uncharacterized protein. (285 aa)
PV08_04964Uncharacterized protein; Belongs to the GST superfamily. (254 aa)
PV08_02306L-serine ammonia-lyase. (647 aa)
PV08_02477GTP cyclohydrolase I. (265 aa)
PV08_02562Methyltransf_25 domain-containing protein. (243 aa)
PV08_02637Uncharacterized protein. (187 aa)
PV08_03183Molybdenum cofactor biosynthesis protein A. (451 aa)
PV08_00011Uncharacterized protein. (248 aa)
PV08_00514Carrier domain-containing protein. (2617 aa)
PV08_00774ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (343 aa)
PV08_00909Uncharacterized protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. (411 aa)
PV08_01004Uncharacterized protein. (264 aa)
PV08_01069Uncharacterized protein; Belongs to the 5'-nucleotidase family. (638 aa)
PV08_11780Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (259 aa)
PV08_04938Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (450 aa)
PV08_04634ThiF domain-containing protein. (715 aa)
PV08_11211Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (319 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (533 aa)
PV08_04935MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (499 aa)
PV08_02696Uncharacterized protein. (536 aa)
PV08_02413FAD_binding_3 domain-containing protein. (629 aa)
PV08_02478Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (761 aa)
PV08_02563Uncharacterized protein. (652 aa)
PV08_02881Uncharacterized protein. (293 aa)
PV08_02573Uncharacterized protein. (1135 aa)
PV08_02603Uncharacterized protein. (268 aa)
PV08_02698Uncharacterized protein. (176 aa)
PV08_03182Molybdenum cofactor biosynthesis protein C. (495 aa)
PV08_10784MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (503 aa)
PV08_10951CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (898 aa)
PV08_09056NmrA domain-containing protein. (322 aa)
PV08_00141Biotin-[acetyl-CoA-carboxylase] ligase. (742 aa)
PV08_00186Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (643 aa)
PV08_09079Nudix hydrolase domain-containing protein. (321 aa)
PV08_10552Uncharacterized protein. (345 aa)
PV08_10366Uncharacterized protein. (613 aa)
PV08_10096DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (424 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (267 aa)
PV08_10807Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
PV08_11013Uncharacterized protein. (376 aa)
PV08_08293Uncharacterized protein. (302 aa)
PV08_08749FAD_binding_3 domain-containing protein. (406 aa)
PV08_088775-formyltetrahydrofolate cyclo-ligase. (246 aa)
PV08_02126Uncharacterized protein. (650 aa)
PV08_01961Dephospho-CoA kinase. (284 aa)
PV08_01931Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (725 aa)
PV08_01141NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (268 aa)
PV08_01056FAD_binding_3 domain-containing protein. (546 aa)
PV08_03297Uncharacterized protein. (162 aa)
PV08_03146Uncharacterized protein. (149 aa)
PV08_02590Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (314 aa)
hxBMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (849 aa)
PV08_04736Uncharacterized protein. (256 aa)
PV08_04676Uncharacterized protein. (277 aa)
PV08_04408Fungal_trans domain-containing protein. (555 aa)
PV08_06428MOSC domain-containing protein. (317 aa)
PV08_07807CFEM domain-containing protein. (315 aa)
PV08_06328Uncharacterized protein. (540 aa)
PV08_05508MINDY_DUB domain-containing protein. (1015 aa)
cnxHMolybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (187 aa)
PV08_07784FSH1 domain-containing protein. (249 aa)
PV08_07210Uncharacterized protein; Belongs to the GST superfamily. (280 aa)
PV08_08700Metallophos domain-containing protein. (616 aa)
PV08_08690Uncharacterized protein; Belongs to the GST superfamily. (266 aa)
PV08_08134Uncharacterized protein; Belongs to the GST superfamily. (817 aa)
PV08_07882FAD_binding_3 domain-containing protein. (714 aa)
PV08_05449Uncharacterized protein. (134 aa)
PV08_05381Uncharacterized protein. (343 aa)
PV08_05795Uncharacterized protein. (410 aa)
PV08_05905Uncharacterized protein. (593 aa)
PV08_00466Uncharacterized protein. (691 aa)
PV08_05995Uncharacterized protein. (127 aa)
PV08_09990Uncharacterized protein. (318 aa)
PV08_09609Uncharacterized protein. (244 aa)
PV08_09493Carrier domain-containing protein. (2576 aa)
PV08_09488Carrier domain-containing protein. (2100 aa)
PV08_03971NmrA domain-containing protein. (326 aa)
PV08_03874FAD_binding_3 domain-containing protein. (611 aa)
PV08_03769Uncharacterized protein. (727 aa)
PV08_06551Pantothenate kinase. (441 aa)
PV08_05442Uncharacterized protein. (626 aa)
PV08_07460Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (270 aa)
PV08_06015FAD-binding FR-type domain-containing protein. (641 aa)
PV08_06480Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (136 aa)
PV08_06331Uncharacterized protein. (794 aa)
PV08_03993Uncharacterized protein. (617 aa)
PV08_04028Uncharacterized protein. (263 aa)
PV08_06540C2H2-type domain-containing protein. (548 aa)
PV08_03919FAD_binding_3 domain-containing protein. (433 aa)
PV08_04229Uncharacterized protein. (608 aa)
PV08_11975Fungal_trans domain-containing protein. (613 aa)
PV08_05343VOC domain-containing protein. (158 aa)
PV08_05308Amino_oxidase domain-containing protein. (560 aa)
PV08_05213Uncharacterized protein. (534 aa)
PV08_07655FAD_binding_3 domain-containing protein. (465 aa)
PV08_07545Pyridoxal kinase. (340 aa)
PV08_07449Macro domain-containing protein. (396 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (303 aa)
PV08_07442Uncharacterized protein. (320 aa)
PV08_06729Uncharacterized protein. (656 aa)
PV08_06689Cysteine desulfurase, mitochondrial. (509 aa)
PV08_08748Fungal_trans domain-containing protein. (648 aa)
PV08_08468Mur_ligase_M domain-containing protein. (489 aa)
PV08_08641Uncharacterized protein. (2177 aa)
PV08_08407Uncharacterized protein. (720 aa)
PV08_08576Uncharacterized protein. (574 aa)
PV08_084154-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (359 aa)
PV08_08072Uncharacterized protein. (260 aa)
PV08_08335Uncharacterized protein. (584 aa)
PV08_08007Uncharacterized protein. (302 aa)
PV08_07997Uncharacterized protein. (453 aa)
PV08_07967FAD_binding_3 domain-containing protein. (599 aa)
PV08_08050Pyridoxamine 5'-phosphate oxidase. (270 aa)
PV08_09991Carrier domain-containing protein. (2394 aa)
PV08_09662Uncharacterized protein. (334 aa)
PV08_09815Uncharacterized protein. (185 aa)
PV08_09715Uncharacterized protein. (252 aa)
PV08_09630Uncharacterized protein. (420 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (691 aa)
PV08_09163PAPS_reduct domain-containing protein. (325 aa)
PV08_09161Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (387 aa)
PV08_10814BTB domain-containing protein. (339 aa)
PV08_10545Uncharacterized protein. (939 aa)
PV08_00154Uncharacterized protein. (253 aa)
PV08_03060Uncharacterized protein. (261 aa)
PV08_03050NmrA domain-containing protein. (330 aa)
PV08_02920Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (388 aa)
PV08_02679FSH1 domain-containing protein. (271 aa)
PV08_02494Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (738 aa)
PV08_02479Nudix hydrolase domain-containing protein. (415 aa)
PV08_02303GST N-terminal domain-containing protein; Belongs to the GST superfamily. (233 aa)
PV08_10753Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (445 aa)
PV08_10309Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (476 aa)
PV08_11664FAD_binding_3 domain-containing protein. (589 aa)
PV08_11449FAD_binding_3 domain-containing protein. (575 aa)
PV08_10082Flavokinase domain-containing protein. (217 aa)
PV08_11632Uncharacterized protein. (594 aa)
PV08_11287Flavin_Reduct domain-containing protein. (329 aa)
PV08_11282SAT domain-containing protein. (481 aa)
PV08_11295Uncharacterized protein. (333 aa)
PV08_11230Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (476 aa)
PV08_11724Molybdenum cofactor biosynthesis protein A. (428 aa)
PV08_11924Uncharacterized protein. (176 aa)
PV08_02102FAD_binding_3 domain-containing protein. (446 aa)
PV08_01107MFS domain-containing protein. (591 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (364 aa)
PV08_03677FAD_binding_3 domain-containing protein. (602 aa)
PV08_02264FAD_binding_3 domain-containing protein. (407 aa)
PV08_02124MoCF_biosynth domain-containing protein. (278 aa)
PV08_01754T5orf172 domain-containing protein. (778 aa)
PV08_01498Uncharacterized protein. (335 aa)
PV08_01109FSH1 domain-containing protein. (252 aa)
PV08_00282Mitochondrial thiamine pyrophosphate carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (331 aa)
PV08_09500Flavokinase domain-containing protein. (609 aa)
PV08_00618VOC domain-containing protein. (723 aa)
PV08_09601Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1186 aa)
PV08_00638Uncharacterized protein. (264 aa)
PV08_00360Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (469 aa)
PV08_00490Uncharacterized protein. (313 aa)
PV08_01058Fungal_trans domain-containing protein. (675 aa)
PV08_01063FAD_binding_3 domain-containing protein. (434 aa)
PV08_00745Hsp90-like protein. (702 aa)
PV08_01204Uncharacterized protein. (599 aa)
PV08_01170Uncharacterized protein. (654 aa)
PV08_08492Uncharacterized protein. (325 aa)
PV08_01353Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (509 aa)
PV08_08788Uncharacterized protein; Belongs to the GST superfamily. (277 aa)
PV08_02023Uncharacterized protein. (512 aa)
PV08_06740Uncharacterized protein. (701 aa)
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
Server load: low (16%) [HD]
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