27 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_02267	Helicase ATP-binding domain-containing protein. (1253 aa)
	PV08_01269	Protein kinase domain-containing protein. (522 aa)
	PV08_06173	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	PV08_10010	Uncharacterized protein. (1018 aa)
	PV08_03724	Uncharacterized protein. (871 aa)
	PV08_07686	Rhodanese domain-containing protein. (561 aa)
	PV08_08323	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (625 aa)
	PV08_08103	Uncharacterized protein. (391 aa)
	PV08_10214	Histone H2B; Belongs to the histone H2B family. (141 aa)
	PV08_10470	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (265 aa)
	PV08_09279	Uncharacterized protein. (876 aa)
	PV08_09635	14-3-3 family protein epsilon; Belongs to the 14-3-3 family. (273 aa)
	PV08_07322	Uncharacterized protein. (1513 aa)
	PV08_07845	DUF1767 domain-containing protein. (291 aa)
	PV08_05689	Protein kinase domain-containing protein. (311 aa)
	PV08_03907	Uncharacterized protein. (1179 aa)
	PV08_04860	Uncharacterized protein. (683 aa)
	PV08_03422	Protein kinase domain-containing protein. (538 aa)
	PV08_00960	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (463 aa)
	PV08_02150	Uncharacterized protein. (467 aa)
	PV08_06415	FHA domain-containing protein. (731 aa)
	PV08_02361	Uncharacterized protein. (1359 aa)
	PV08_00894	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2287 aa)
	PV08_01029	Uncharacterized protein. (1037 aa)
	PV08_01919	Protein kinase domain-containing protein. (746 aa)
	PV08_05176	Uncharacterized protein. (308 aa)
	PV08_04352	Uncharacterized protein. (379 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00894	PV08_00960	A0A0D2C9R0	A0A0D2BPE0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.914
PV08_00894	PV08_01029	A0A0D2C9R0	A0A0D2CA72	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.986
PV08_00894	PV08_01269	A0A0D2C9R0	A0A0D2A7E2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.914
PV08_00894	PV08_01919	A0A0D2C9R0	A0A0D2CCV9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.914
PV08_00894	PV08_02267	A0A0D2C9R0	A0A0D2AA93	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Helicase ATP-binding domain-containing protein.	0.900
PV08_00894	PV08_02361	A0A0D2C9R0	A0A0D2C399	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.931
PV08_00894	PV08_03422	A0A0D2C9R0	A0A0D2BKM5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.990
PV08_00894	PV08_03724	A0A0D2C9R0	A0A0D1YNA6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.900
PV08_00894	PV08_03907	A0A0D2C9R0	A0A0D2BCL3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.761
PV08_00894	PV08_04352	A0A0D2C9R0	A0A0D1YPM7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.737
PV08_00894	PV08_04860	A0A0D2C9R0	A0A0D2BGA7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.970
PV08_00894	PV08_05176	A0A0D2C9R0	A0A0D1YRX9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.900
PV08_00894	PV08_05689	A0A0D2C9R0	A0A0D2BAM8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.914
PV08_00894	PV08_06173	A0A0D2C9R0	A0A0D1ZTL9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.980
PV08_00894	PV08_07322	A0A0D2C9R0	A0A0D2B6P6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.900
PV08_00894	PV08_07686	A0A0D2C9R0	A0A0D1YIY6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Rhodanese domain-containing protein.	0.830
PV08_00894	PV08_07845	A0A0D2C9R0	A0A0D2B852	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	DUF1767 domain-containing protein.	0.759
PV08_00894	PV08_08323	A0A0D2C9R0	A0A0D1YDN6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.762
PV08_00894	PV08_09279	A0A0D2C9R0	A0A0D2B022	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.984
PV08_00894	PV08_10010	A0A0D2C9R0	A0A0D1ZIQ1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.900