125 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_10402	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (179 aa)
	PV08_09829	Uncharacterized protein. (304 aa)
	PV08_08054	Uncharacterized protein. (308 aa)
	PV08_08119	Uncharacterized protein. (1202 aa)
	PV08_08129	U1-type domain-containing protein. (297 aa)
	PV08_08164	Uncharacterized protein. (1227 aa)
	PV08_08189	Cir_N domain-containing protein. (396 aa)
	PV08_08344	Uncharacterized protein. (243 aa)
	PV08_06833	RRM domain-containing protein. (155 aa)
	PV08_07311	RED_N domain-containing protein. (522 aa)
	PV08_07697	DUF2040 domain-containing protein. (405 aa)
	PV08_05665	Uncharacterized protein. (325 aa)
	PV08_05967	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (127 aa)
	PV08_06233	Uncharacterized protein. (335 aa)
	PV08_06323	Uncharacterized protein. (253 aa)
	PV08_06393	F-box domain-containing protein. (602 aa)
	PV08_03941	Uncharacterized protein. (990 aa)
	PV08_04278	RRM domain-containing protein. (297 aa)
	PV08_04493	Sm domain-containing protein. (92 aa)
	PV08_02580	Pre-mRNA-processing protein 45. (582 aa)
	PV08_02685	Matrin-type domain-containing protein. (235 aa)
	PV08_03342	DUF1716 domain-containing protein. (608 aa)
	PV08_03551	Prp18 domain-containing protein. (386 aa)
	PV08_00382	C2H2-type domain-containing protein. (175 aa)
	PV08_00957	RRM domain-containing protein. (328 aa)
	PV08_01037	Tr-type G domain-containing protein. (982 aa)
	PV08_01581	Uncharacterized protein. (253 aa)
	PV08_01757	Uncharacterized protein. (1231 aa)
	PV08_01877	C2H2-type domain-containing protein. (907 aa)
	PV08_01907	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43. (763 aa)
	PV08_11609	Uncharacterized protein. (583 aa)
	PV08_10219	HET domain-containing protein. (288 aa)
	PV08_09108	RING-type domain-containing protein. (750 aa)
	PV08_09374	Uncharacterized protein. (289 aa)
	PV08_09845	PSP domain-containing protein. (580 aa)
	PV08_09697	WD_REPEATS_REGION domain-containing protein. (588 aa)
	PV08_02039	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (174 aa)
	PV08_01949	Uncharacterized protein. (605 aa)
	PV08_01648	Uncharacterized protein. (782 aa)
	PV08_01628	Small nuclear ribonucleoprotein Sm D2. (103 aa)
	PV08_01548	Small nuclear ribonucleoprotein Sm D3. (150 aa)
	PV08_01372	RRM domain-containing protein. (203 aa)
	PV08_01124	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa)
	PV08_00243	WD_REPEATS_REGION domain-containing protein. (506 aa)
	PV08_00121	Small nuclear ribonucleoprotein G. (80 aa)
	PV08_03467	CVNH domain-containing protein. (396 aa)
	PV08_03359	Pre-mRNA-processing-splicing factor 8. (2358 aa)
	PV08_03208	Uncharacterized protein. (209 aa)
	PV08_03153	Uncharacterized protein. (251 aa)
	PV08_04989	PPIase cyclophilin-type domain-containing protein. (617 aa)
	PV08_03847	Uncharacterized protein. (208 aa)
	PV08_03817	Uncharacterized protein. (157 aa)
	PV08_05834	Uncharacterized protein. (492 aa)
	PV08_05647	Uncharacterized protein. (958 aa)
	PV08_07716	Uncharacterized protein. (174 aa)
	PV08_07589	Uncharacterized protein. (662 aa)
	PV08_02025	MFAP1 domain-containing protein. (521 aa)
	PV08_07001	Slu7 domain-containing protein. (495 aa)
	PV08_06800	Isochorismatase domain-containing protein. (315 aa)
	PV08_01805	Pre-mRNA-splicing factor prp46. (463 aa)
	PV08_01499	Uncharacterized protein. (980 aa)
	PV08_01408	Uncharacterized protein. (216 aa)
	PV08_08552	Uncharacterized protein. (684 aa)
	PV08_01743	Uncharacterized protein. (558 aa)
	PV08_00613	Uncharacterized protein. (529 aa)
	PV08_00598	RRM domain-containing protein. (317 aa)
	PV08_09363	PPIase cyclophilin-type domain-containing protein. (563 aa)
	PV08_10880	Pre-mRNA-splicing factor slt11. (373 aa)
	PV08_03363	Uncharacterized protein. (547 aa)
	PV08_03047	Uncharacterized protein. (516 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
	PV08_02593	PUM-HD domain-containing protein. (992 aa)
	PV08_02846	Pre-mRNA-splicing factor clf1. (675 aa)
	PV08_10098	Pre-mRNA-splicing factor cwc15. (288 aa)
	PV08_11598	Uncharacterized protein. (224 aa)
	PV08_04664	Uncharacterized protein. (584 aa)
	PV08_04963	WD_REPEATS_REGION domain-containing protein. (1302 aa)
	PV08_11886	CID domain-containing protein. (955 aa)
	PV08_11450	Protein kinase domain-containing protein. (749 aa)
	PV08_10616	Uncharacterized protein. (299 aa)
	PV08_09124	Uncharacterized protein. (1669 aa)
	PV08_09164	J domain-containing protein. (212 aa)
	PV08_09708	Sm domain-containing protein. (227 aa)
	PV08_06772	Branchpoint-bridging protein. (554 aa)
	PV08_06792	Matrin-type domain-containing protein. (514 aa)
	PV08_07783	FHA domain-containing protein. (293 aa)
	PV08_06197	PHD finger-like domain-containing protein 5B. (110 aa)
	PV08_03925	Uncharacterized protein. (1466 aa)
	PV08_04337	Pre-mRNA-splicing factor cwc22. (959 aa)
	PV08_04377	Uncharacterized protein. (764 aa)
	PV08_04492	Uncharacterized protein. (90 aa)
	PV08_07239	Uncharacterized protein. (209 aa)
	PV08_08005	Uncharacterized protein. (371 aa)
	PV08_07452	PH domain-containing protein. (1067 aa)
	PV08_07342	Uncharacterized protein. (291 aa)
	PV08_07267	G-patch domain-containing protein. (661 aa)
	PV08_07150	Uncharacterized protein. (151 aa)
	PV08_08876	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (93 aa)
	PV08_08806	Uncharacterized protein. (188 aa)
	PV08_08904	Uncharacterized protein. (248 aa)
	PV08_08100	G-patch domain-containing protein. (711 aa)
	PV08_11044	Uncharacterized protein. (516 aa)
	PV08_03924	SAP domain-containing protein. (644 aa)
	PV08_03888	SNRNP27 domain-containing protein. (197 aa)
	PV08_04043	Uncharacterized protein. (2238 aa)
	PV08_06196	Pinin_SDK_memA domain-containing protein. (337 aa)
	PV08_05598	Uncharacterized protein. (524 aa)
	PV08_05531	WD_REPEATS_REGION domain-containing protein. (365 aa)
	PV08_07670	RRM domain-containing protein. (116 aa)
	PV08_07640	Tudor domain-containing protein. (292 aa)
	PV08_07580	Sde2_N_Ubi domain-containing protein. (335 aa)
	PV08_04518	Cwf21 domain-containing protein. (179 aa)
	PV08_04528	Uncharacterized protein. (679 aa)
	PV08_02388	Uncharacterized protein. (694 aa)
	PV08_02849	Nop domain-containing protein. (596 aa)
	PV08_03449	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (471 aa)
	PV08_00496	WD_REPEATS_REGION domain-containing protein. (567 aa)
	PV08_00636	Uncharacterized protein. (396 aa)
	PV08_00686	RRM domain-containing protein. (164 aa)
	PV08_01550	Uncharacterized protein. (438 aa)
	PV08_01861	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (191 aa)
	PV08_02056	Uncharacterized protein. (222 aa)
	PV08_11118	PWI domain-containing protein. (470 aa)
	PV08_11138	Uncharacterized protein. (670 aa)
	PV08_11421	C2H2-type domain-containing protein. (216 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM8	PV08_00121	A0A0D2BI95	A0A0D2C7N2	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein G.	0.988
LSM8	PV08_00243	A0A0D2BI95	A0A0D2C7W4	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	WD_REPEATS_REGION domain-containing protein.	0.988
LSM8	PV08_00636	A0A0D2BI95	A0A0D1YXR9	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.717
LSM8	PV08_00957	A0A0D2BI95	A0A0D2A6H7	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	RRM domain-containing protein.	0.699
LSM8	PV08_01037	A0A0D2BI95	A0A0D2A6S5	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Tr-type G domain-containing protein.	0.989
LSM8	PV08_01372	A0A0D2BI95	A0A0D2CB53	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	RRM domain-containing protein.	0.842
LSM8	PV08_01408	A0A0D2BI95	A0A0D2BQT2	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.571
LSM8	PV08_01548	A0A0D2BI95	A0A0D2CBT6	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3.	0.964
LSM8	PV08_01550	A0A0D2BI95	A0A0D1Z090	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.964
LSM8	PV08_01581	A0A0D2BI95	A0A0D2A8C7	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.871
LSM8	PV08_01628	A0A0D2BI95	A0A0D2CC56	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D2.	0.991
LSM8	PV08_01648	A0A0D2BI95	A0A0D2CC69	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.609
LSM8	PV08_01805	A0A0D2BI95	A0A0D2BS18	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA-splicing factor prp46.	0.609
LSM8	PV08_01861	A0A0D2BI95	A0A0D1Z0W4	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.842
LSM8	PV08_02025	A0A0D2BI95	A0A0D2BSP5	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	MFAP1 domain-containing protein.	0.681
LSM8	PV08_02039	A0A0D2BI95	A0A0D2CD67	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.463
LSM8	PV08_02580	A0A0D2BI95	A0A0D1ZZY4	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA-processing protein 45.	0.618
LSM8	PV08_02685	A0A0D2BI95	A0A0D2A081	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Matrin-type domain-containing protein.	0.905
LSM8	PV08_02849	A0A0D2BI95	A0A0D1YTL2	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Nop domain-containing protein.	0.994
LSM8	PV08_03153	A0A0D2BI95	A0A0D2C5L0	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.400