54 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_01966	Uncharacterized protein. (370 aa)
	PV08_10350	Ubiquitin-40S ribosomal protein S27a. (154 aa)
	PV08_10852	cAMP-dependent protein kinase regulatory subunit. (451 aa)
	PV08_09235	OTU domain-containing protein. (415 aa)
	PV08_09798	Uncharacterized protein. (622 aa)
	PV08_07194	Uncharacterized protein. (172 aa)
	PV08_05961	Uncharacterized protein. (154 aa)
	PV08_06182	Uncharacterized protein. (808 aa)
	PV08_04462	Rap-GAP domain-containing protein. (1432 aa)
	PV08_02464	Metallophos domain-containing protein. (427 aa)
	PV08_02874	Protein kinase domain-containing protein. (1269 aa)
	PV08_03361	Fork-head domain-containing protein. (405 aa)
	PV08_00098	Guanylate cyclase domain-containing protein. (448 aa)
	PV08_00616	PIPK domain-containing protein. (969 aa)
	PV08_01951	Uncharacterized protein. (827 aa)
	PV08_11743	Zn(2)-C6 fungal-type domain-containing protein. (710 aa)
	PV08_09069	Uncharacterized protein. (1017 aa)
	PV08_09341	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1171 aa)
	PV08_09422	Uncharacterized protein. (287 aa)
	PV08_08530	Uncharacterized protein. (457 aa)
	PV08_08655	Uncharacterized protein. (185 aa)
	PV08_05217	Uncharacterized protein. (818 aa)
	PV08_04373	Uncharacterized protein. (1305 aa)
	PV08_02976	Uncharacterized protein. (919 aa)
	PV08_11376	BZIP domain-containing protein. (465 aa)
	PV08_11507	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (348 aa)
	PV08_11378	Zn(2)-C6 fungal-type domain-containing protein. (745 aa)
	PV08_11389	Non-specific serine/threonine protein kinase. (984 aa)
	PV08_10252	Uncharacterized protein. (582 aa)
	PV08_10773	Uncharacterized protein. (1582 aa)
	PV08_08057	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (679 aa)
	PV08_07860	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (347 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (634 aa)
	PV08_06181	cAMP-dependent protein kinase type 2; Belongs to the protein kinase superfamily. (421 aa)
	PV08_04757	Uncharacterized protein. (1448 aa)
	PV08_11493	Uncharacterized protein. (845 aa)
	PV08_11568	PIPK domain-containing protein. (348 aa)
	PV08_10118	Protein kinase domain-containing protein. (266 aa)
	PV08_02766	Protein kinase domain-containing protein. (861 aa)
	GUF1	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (659 aa)
	PV08_10885	MIT domain-containing protein. (1177 aa)
	PV08_00125	Non-specific serine/threonine protein kinase. (642 aa)
	PV08_00663	Protein kinase domain-containing protein. (822 aa)
	PV08_00455	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2505 aa)
	PV08_00810	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (325 aa)
	PV08_08176	Zn(2)-C6 fungal-type domain-containing protein. (738 aa)
	PV08_08612	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (274 aa)
	PV08_01928	Ubiquitin-like domain-containing protein. (592 aa)
	PV08_01965	Serine/threonine-protein phosphatase. (329 aa)
	PV08_07403	Repressor of RNA polymerase III transcription MAF1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (358 aa)
	PV08_07428	WD_REPEATS_REGION domain-containing protein. (537 aa)
	PV08_07741	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (323 aa)
	PV08_06100	Uncharacterized protein. (621 aa)
	PV08_00223	Polyubiquitin. (305 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GUF1	PV08_00223	A0A0D2BI52	A0A0D2C7U5	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Polyubiquitin.	0.526
GUF1	PV08_01928	A0A0D2BI52	A0A0D2BQS0	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Ubiquitin-like domain-containing protein.	0.565
GUF1	PV08_10350	A0A0D2BI52	A0A0D1Y801	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Ubiquitin-40S ribosomal protein S27a.	0.565
GUF1	PV08_10885	A0A0D2BI52	A0A0D2BJY9	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	MIT domain-containing protein.	0.649
GUF1	PV08_11376	A0A0D2BI52	A0A0D2AUK8	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	BZIP domain-containing protein.	0.565
MDM34	PV08_01965	A0A0D2BA20	A0A0D2BSH9	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Serine/threonine-protein phosphatase.	0.421
MDM34	PV08_02464	A0A0D2BA20	A0A0D1YSE9	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Metallophos domain-containing protein.	0.421
MDM34	PV08_08176	A0A0D2BA20	A0A0D2BPI7	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Zn(2)-C6 fungal-type domain-containing protein.	0.863
MDM34	PV08_08612	A0A0D2BA20	A0A0D2BQL6	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.863
MDM34	PV08_11378	A0A0D2BA20	A0A0D2AVD9	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Zn(2)-C6 fungal-type domain-containing protein.	0.863
MDM34	PV08_11743	A0A0D2BA20	A0A0D1ZAE9	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Zn(2)-C6 fungal-type domain-containing protein.	0.863
PV08_00098	PV08_00125	A0A0D1YWA0	A0A0D2BKU7	Guanylate cyclase domain-containing protein.	Non-specific serine/threonine protein kinase.	0.544
PV08_00098	PV08_00810	A0A0D1YWA0	A0A0D2BNX6	Guanylate cyclase domain-containing protein.	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.	0.578
PV08_00098	PV08_06181	A0A0D1YWA0	A0A0D2BBY6	Guanylate cyclase domain-containing protein.	cAMP-dependent protein kinase type 2; Belongs to the protein kinase superfamily.	0.578
PV08_00098	PV08_07741	A0A0D1YWA0	A0A0D2BUP9	Guanylate cyclase domain-containing protein.	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.	0.578
PV08_00098	PV08_07860	A0A0D1YWA0	A0A0D2B859	Guanylate cyclase domain-containing protein.	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.	0.578
PV08_00098	PV08_09341	A0A0D1YWA0	A0A0D1ZGH5	Guanylate cyclase domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.622
PV08_00098	PV08_09798	A0A0D1YWA0	A0A0D1YCB5	Guanylate cyclase domain-containing protein.	Uncharacterized protein.	0.544
PV08_00098	PV08_10118	A0A0D1YWA0	A0A0D2BHH8	Guanylate cyclase domain-containing protein.	Protein kinase domain-containing protein.	0.622
PV08_00098	PV08_10852	A0A0D1YWA0	A0A0D1Y9A9	Guanylate cyclase domain-containing protein.	cAMP-dependent protein kinase regulatory subunit.	0.900