94 items (Exophiala spinifera) - STRING interaction network

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PV08_04406	GAR domain-containing protein. (1071 aa)
	PV08_06516	Uncharacterized protein. (245 aa)
	PV08_03936	CP-type G domain-containing protein. (663 aa)
	PV08_04037	18S rRNA biogenesis protein RCL1. (406 aa)
	PV08_04238	WD_REPEATS_REGION domain-containing protein. (960 aa)
	PV08_04388	Uncharacterized protein. (1030 aa)
	PV08_04666	WD_REPEATS_REGION domain-containing protein. (963 aa)
	PV08_00617	Ribosomal RNA small subunit methyltransferase NEP1. (256 aa)
	PV08_00622	Uncharacterized protein. (710 aa)
	PV08_00837	Exonuclease domain-containing protein. (354 aa)
	PV08_00857	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (659 aa)
	PV08_01405	WD_REPEATS_REGION domain-containing protein. (990 aa)
	PV08_02132	Tr-type G domain-containing protein. (1082 aa)
	PV08_11378	Zn(2)-C6 fungal-type domain-containing protein. (745 aa)
	PV08_11579	Exonuclease domain-containing protein. (258 aa)
	PV08_10563	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (217 aa)
	PV08_10475	Uncharacterized protein. (684 aa)
	PV08_10950	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (205 aa)
	PV08_11002	WD_REPEATS_REGION domain-containing protein. (984 aa)
	PV08_09459	Nop domain-containing protein. (517 aa)
	PV08_09506	Uncharacterized protein. (721 aa)
	PV08_09817	Nucleolar protein 58. (632 aa)
	PV08_08180	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (371 aa)
	PV08_08142	Uncharacterized protein. (303 aa)
	PV08_08591	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (743 aa)
	PV08_08573	Kri1_C domain-containing protein. (601 aa)
	PV08_08884	Uncharacterized protein. (188 aa)
	PV08_08934	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1398 aa)
	PV08_08733	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (442 aa)
	PV08_06744	Utp12 domain-containing protein. (934 aa)
	PV08_06879	Protein kinase domain-containing protein. (294 aa)
	PV08_07454	C2H2-type domain-containing protein. (520 aa)
	PV08_07785	CP-type G domain-containing protein. (549 aa)
	PV08_07650	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (591 aa)
	PV08_06111	Bms1-type G domain-containing protein. (1179 aa)
	PV08_04284	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (124 aa)
	PV08_03960	Uncharacterized protein. (379 aa)
	PV08_03975	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (334 aa)
	PV08_04110	Fcf2 domain-containing protein. (228 aa)
	PV08_11970	Uncharacterized protein. (790 aa)
	PV08_04396	Uncharacterized protein. (126 aa)
	PV08_02481	WD_REPEATS_REGION domain-containing protein. (864 aa)
	PV08_02558	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (356 aa)
	PV08_03338	Uncharacterized protein. (369 aa)
	PV08_03466	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (388 aa)
	PV08_03139	rRNA 2'-O-methyltransferase fibrillarin. (324 aa)
	PV08_10941	Uncharacterized protein. (388 aa)
	PV08_03280	BP28CT domain-containing protein. (1827 aa)
	PV08_09460	Uncharacterized protein. (233 aa)
	PV08_00538	Exonuclease domain-containing protein. (790 aa)
	PV08_09841	RNase III domain-containing protein. (313 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (248 aa)
	PV08_08176	Zn(2)-C6 fungal-type domain-containing protein. (738 aa)
	PV08_08186	Uncharacterized protein. (133 aa)
	PV08_08236	Uncharacterized protein. (739 aa)
	PV08_01617	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (519 aa)
	PV08_08612	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (274 aa)
	PV08_08617	Brix domain-containing protein. (296 aa)
	PV08_08732	H/ACA ribonucleoprotein complex subunit 3. (64 aa)
	PV08_06755	Importin N-terminal domain-containing protein. (1072 aa)
	PV08_01815	RIO domain-containing protein. (382 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1129 aa)
	PV08_07318	WD_REPEATS_REGION domain-containing protein. (603 aa)
	PV08_07766	U3 small nucleolar RNA-associated protein 22. (1121 aa)
	PV08_04034	Bromo domain-containing protein. (352 aa)
	PV08_04104	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (186 aa)
	PV08_04914	PINc domain-containing protein. (194 aa)
	PV08_05034	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (583 aa)
	PV08_01819	Spindle pole body component. (761 aa)
	PV08_11147	Uncharacterized protein. (504 aa)
	PV08_11379	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (437 aa)
	PV08_11385	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1038 aa)
	PV08_10636	Uncharacterized protein. (403 aa)
	PV08_09089	Ribonuclease P protein subunit. (289 aa)
	PV08_07535	Exonuclease domain-containing protein. (648 aa)
	PV08_07823	zf-C2H2_2 domain-containing protein. (311 aa)
	PV08_07878	WD_REPEATS_REGION domain-containing protein. (533 aa)
	PV08_04272	TAP-C domain-containing protein. (430 aa)
	PV08_03155	Uncharacterized protein. (296 aa)
	PV08_01126	Uncharacterized protein. (1089 aa)
	PV08_01156	RAI1 domain-containing protein. (394 aa)
	PV08_01268	Centromere/microtubule-binding protein cbf5. (504 aa)
	PV08_01826	Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (207 aa)
	PV08_01901	S4 RNA-binding domain-containing protein. (188 aa)
	PV08_02131	DUF4604 domain-containing protein. (187 aa)
	PV08_11743	Zn(2)-C6 fungal-type domain-containing protein. (710 aa)
	PV08_09170	Glyco_hydro_cc domain-containing protein. (736 aa)
	PV08_09266	tRNA pseudouridine(55) synthase. (424 aa)
	PV08_08575	Uncharacterized protein. (459 aa)
	PV08_06743	Uncharacterized protein. (987 aa)
	PV08_06893	Uncharacterized protein. (938 aa)
	PV08_07531	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (266 aa)
	PV08_05757	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4840 aa)
	PV08_06133	WD_REPEATS_REGION domain-containing protein. (1505 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NAT10	PV08_00617	A0A0D2BS61	A0A0D2A5L6	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribosomal RNA small subunit methyltransferase NEP1.	0.985
NAT10	PV08_00857	A0A0D2BS61	A0A0D2A660	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.876
NAT10	PV08_01268	A0A0D2BS61	A0A0D1YZF4	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Centromere/microtubule-binding protein cbf5.	0.954
NAT10	PV08_01405	A0A0D2BS61	A0A0D2A7R1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	WD_REPEATS_REGION domain-containing protein.	0.994
NAT10	PV08_01617	A0A0D2BS61	A0A0D2BQ31	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.833
NAT10	PV08_01815	A0A0D2BS61	A0A0D2BS26	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	RIO domain-containing protein.	0.693
NAT10	PV08_01901	A0A0D2BS61	A0A0D1Z0Z2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	S4 RNA-binding domain-containing protein.	0.952
NAT10	PV08_02481	A0A0D2BS61	A0A0D2BGR1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	WD_REPEATS_REGION domain-containing protein.	0.997
NAT10	PV08_03139	A0A0D2BS61	A0A0D2BJT2	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	rRNA 2'-O-methyltransferase fibrillarin.	0.991
NAT10	PV08_03155	A0A0D2BS61	A0A0D1YUD5	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.991
NAT10	PV08_03280	A0A0D2BS61	A0A0D2BKA4	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	BP28CT domain-containing protein.	0.994
NAT10	PV08_03936	A0A0D2BS61	A0A0D1ZVK3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	CP-type G domain-containing protein.	0.866
NAT10	PV08_04037	A0A0D2BS61	A0A0D1ZVW7	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	18S rRNA biogenesis protein RCL1.	0.985
NAT10	PV08_04110	A0A0D2BS61	A0A0D2BEA1	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Fcf2 domain-containing protein.	0.966
NAT10	PV08_04238	A0A0D2BS61	A0A0D1ZWJ9	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	WD_REPEATS_REGION domain-containing protein.	0.992
NAT10	PV08_04284	A0A0D2BS61	A0A0D2BDS0	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.978
NAT10	PV08_04388	A0A0D2BS61	A0A0D1ZWX3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Uncharacterized protein.	0.997
NAT10	PV08_04666	A0A0D2BS61	A0A0D1ZXW9	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	WD_REPEATS_REGION domain-containing protein.	0.995
NAT10	PV08_04914	A0A0D2BS61	A0A0D2C236	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	PINc domain-containing protein.	0.976
NAT10	PV08_05034	A0A0D2BS61	A0A0D2C2H3	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.827