STRINGSTRING
AS27_09394 AS27_09394 AS27_00226 AS27_00226 AS27_10691 AS27_10691 AS27_10958 AS27_10958 AS27_04274 AS27_04274 AS27_03101 AS27_03101 AS27_10039 AS27_10039 AS27_04347 AS27_04347 AS27_01336 AS27_01336 AS27_01352 AS27_01352 AS27_05279 AS27_05279 AS27_00180 AS27_00180 AS27_02179 AS27_02179 AS27_02738 AS27_02738 AS27_09522 AS27_09522 AS27_04472 AS27_04472 AS27_09949 AS27_09949 AS27_09958 AS27_09958 AS27_08574 AS27_08574 AS27_14858 AS27_14858 AS27_08699 AS27_08699 AS27_04072 AS27_04072 AS27_07767 AS27_07767 AS27_12189 AS27_12189 AS27_12204 AS27_12204 AS27_12341 AS27_12341 AS27_10088 AS27_10088 AS27_01650 AS27_01650 AS27_02990 AS27_02990 AS27_14124 AS27_14124 AS27_12467 AS27_12467 AS27_05580 AS27_05580
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AS27_09394PRKR-interacting protein 1. (148 aa)
AS27_00226Exonuclease 1. (684 aa)
AS27_10691DNA polymerase delta subunit 3. (442 aa)
AS27_10958DNA polymerase delta subunit 2. (459 aa)
AS27_04274Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
AS27_03101Replication factor C subunit 3. (327 aa)
AS27_10039DNA mismatch repair protein Mlh1. (713 aa)
AS27_04347DNA mismatch repair protein Msh6; Component of the post-replicative DNA mismatch repair system (MMR). (1152 aa)
AS27_01336Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (193 aa)
AS27_01352Replication factor C subunit 5. (318 aa)
AS27_05279Replication factor C subunit 2. (316 aa)
AS27_00180Apoptosis-enhancing nuclease. (316 aa)
AS27_02179PMS1 protein 1. (921 aa)
AS27_02738CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (385 aa)
AS27_09522Replication factor C subunit 1. (1174 aa)
AS27_04472DNA mismatch repair protein Mlh3. (1443 aa)
AS27_09949Cell cycle checkpoint protein RAD17. (679 aa)
AS27_09958DNA mismatch repair protein Msh3. (656 aa)
AS27_08574Coiled-coil domain-containing protein 94. (183 aa)
AS27_14858MutS protein 5. (794 aa)
AS27_08699F-box only protein 18. (1023 aa)
AS27_04072Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
AS27_07767DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (863 aa)
AS27_12189Replication protein A 14 kDa subunit. (82 aa)
AS27_12204Mismatch repair endonuclease PMS2. (887 aa)
AS27_12341Meiosis-specific with OB domain-containing protein. (470 aa)
AS27_10088Replication protein A 32 kDa subunit. (232 aa)
AS27_01650RNA exonuclease 4. (377 aa)
AS27_02990ATPase family AAA domain-containing protein 5. (1778 aa)
AS27_14124Replication factor C subunit 4. (364 aa)
AS27_12467Uncharacterized protein. (142 aa)
AS27_05580General transcription factor 3C polypeptide 6. (197 aa)
Your Current Organism:
Aptenodytes forsteri
NCBI taxonomy Id: 9233
Other names: A. forsteri, emperor penguin
Server load: low (34%) [HD]