STRINGSTRING
NBR1 NBR1 ATG3 ATG3 ATG16L1 ATG16L1 WIPI1 WIPI1 MAP1LC3A MAP1LC3A WIPI2 WIPI2 ATG5 ATG5 ATG7 ATG7 SQSTM1 SQSTM1 GABARAPL2 GABARAPL2 GABARAPL1 GABARAPL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NBR1Next to BRCA1 1. (981 aa)
ATG3Autophagy-related protein 3. (293 aa)
ATG16L1Autophagy-related protein 16-1. (593 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1. (410 aa)
MAP1LC3AMicrotubule-associated proteins 1A/1B light chain 3A. (108 aa)
WIPI2WD repeat domain phosphoinositide-interacting protein 2. (411 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (701 aa)
SQSTM1Sequestosome-1. (398 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (87 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (120 aa)
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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