STRINGSTRING
APPL1 APPL1 AS28_09798 AS28_09798 MED1 MED1 AS28_03264 AS28_03264 GCLM GCLM GCLC GCLC APPL2 APPL2 LGMN LGMN IL10 IL10 HGF HGF VIL1 VIL1 AS28_04570 AS28_04570
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APPL1DCC-interacting protein 13-alpha. (699 aa)
AS28_09798Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (511 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1574 aa)
AS28_03264Cyclic AMP-responsive element-binding protein 1. (351 aa)
GCLMGlutamate--cysteine ligase regulatory subunit. (231 aa)
GCLCGlutamate--cysteine ligase catalytic subunit. (586 aa)
APPL2DCC-interacting protein 13-beta. (641 aa)
LGMNLegumain. (430 aa)
IL10Interleukin-10. (119 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (701 aa)
VIL1Villin-1. (820 aa)
AS28_04570Interleukin-10. (102 aa)
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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