STRINGSTRING
AS28_06835 AS28_06835 AS28_13795 AS28_13795 RNFT1 RNFT1 LPCAT3 LPCAT3 TRIM32 TRIM32 AS28_09396 AS28_09396 AS28_04463 AS28_04463 AS28_03247 AS28_03247 TNFSF10 TNFSF10 FAM162A FAM162A GSK3B GSK3B F3 F3 FGF2 FGF2 CDC20 CDC20 APH1A APH1A PSEN1 PSEN1 IST1 IST1 CCBE1 CCBE1 SIRT6 SIRT6 NRD1 NRD1 RFWD2 RFWD2 PSME3 PSME3 WDR20 WDR20 FBXW8 FBXW8 AS28_06698 AS28_06698 CYR61 CYR61 HIP1R HIP1R CRADD CRADD IFT57 IFT57 CTSH CTSH PARK2 PARK2 TNFSF15 TNFSF15 RPS3 RPS3 TNIP3 TNIP3 BBS7 BBS7 UACA UACA CLPX CLPX AS28_10272 AS28_10272 USP13 USP13 HSPD1 HSPD1 RNF19A RNF19A PLGRKT PLGRKT AS28_13627 AS28_13627 BCL10 BCL10 ACVR1C ACVR1C SOCS4 SOCS4 SMAD7 SMAD7 CLUL1 CLUL1 TMEM130 TMEM130 GPER1 GPER1 BTRC BTRC SART3 SART3 PIDD1 PIDD1 AS28_10182 AS28_10182 GCLC GCLC CSNK1E CSNK1E EIF2AK3 EIF2AK3 ARL6IP5 ARL6IP5 REST REST ASTL ASTL KCNE2 KCNE2 PSMD10 PSMD10 RNF144B RNF144B AS28_05455 AS28_05455 TNFRSF1B TNFRSF1B RHBDD1 RHBDD1 AXIN1 AXIN1 RNF139 RNF139 MALT1 MALT1 LAPTM5 LAPTM5 AS28_11597 AS28_11597 CLN6 CLN6 APAF1 APAF1 AS28_12920 AS28_12920 FASLG FASLG PLK1 PLK1 CASP8AP2 CASP8AP2 AGBL4 AGBL4 FADD FADD CASP8 CASP8 AS28_00351 AS28_00351 CASP2 CASP2 DDA1 DDA1 SGTA SGTA AS28_08649 AS28_08649 LYN LYN AS28_07342 AS28_07342 AS28_02302 AS28_02302 AS28_01302 AS28_01302 TRIB2 TRIB2 LGMN LGMN AS28_15150 AS28_15150 OGT OGT CLEC3B CLEC3B CTSD CTSD ST18 ST18 ZC3H12A ZC3H12A ANKIB1 ANKIB1 BAG2 BAG2 RNF180 RNF180 FBXW11 FBXW11 TMEM259 TMEM259 BID BID ADRM1 ADRM1 AS28_07109 AS28_07109 KLHL40 KLHL40 AKIRIN2 AKIRIN2 PRELID1 PRELID1 RNF144A RNF144A AS28_03580 AS28_03580 RNF14 RNF14 CSNK1D CSNK1D USP50 USP50 CDC20B CDC20B SH3RF1 SH3RF1 FBLN1 FBLN1 ARIH2 ARIH2 PML PML FGFR4 FGFR4 FBXO22 FBXO22 AS28_13250 AS28_13250 PSMC3 PSMC3 PSMC6 PSMC6 AS28_08128 AS28_08128 PSMC2 PSMC2 NUB1 NUB1 LRRK2 LRRK2 TMTC3 TMTC3 ACER2 ACER2 CAV1 CAV1 BAK1 BAK1 RCHY1 RCHY1 PDCD5 PDCD5 AS28_09454 AS28_09454 CAV3 CAV3 GPLD1 GPLD1 RNF217 RNF217 ZER1 ZER1 NGFR NGFR AURKAIP1 AURKAIP1 AS28_08394 AS28_08394 AS28_05270 AS28_05270 CAPN3 CAPN3 DAP DAP SNX9 SNX9 SIRT1 SIRT1 AS28_09591 AS28_09591 RIPK2 RIPK2 PSMD14 PSMD14 DIABLO DIABLO GRAMD4 GRAMD4 PCOLCE2 PCOLCE2 DET1 DET1 AS28_08841 AS28_08841
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AS28_06835p2X purinoceptor 1. (348 aa)
AS28_13795Axin-2. (643 aa)
RNFT1RING finger and transmembrane domain-containing protein 1. (318 aa)
LPCAT3Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (440 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (649 aa)
AS28_09396Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein. (343 aa)
AS28_04463Tumor necrosis factor receptor superfamily member 6. (299 aa)
AS28_03247Caspase-10; Belongs to the peptidase C14A family. (518 aa)
TNFSF10Tumor necrosis factor ligand superfamily member 10; Belongs to the tumor necrosis factor family. (289 aa)
FAM162AProtein FAM162A. (157 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (371 aa)
F3Tissue factor. (260 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (96 aa)
CDC20Cell division cycle protein 20. (439 aa)
APH1AGamma-secretase subunit Aph-1b. (231 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (388 aa)
IST1IST1. (365 aa)
CCBE1Collagen and calcium-binding EGF domain-containing protein 1. (331 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (337 aa)
NRD1Nardilysin; Belongs to the peptidase M16 family. (1056 aa)
RFWD2E3 ubiquitin-protein ligase RFWD2. (610 aa)
PSME3Proteasome activator complex subunit 3. (242 aa)
WDR20WD repeat-containing protein 20. (505 aa)
FBXW8F-box/WD repeat-containing protein 8. (490 aa)
AS28_06698F-box/WD repeat-containing protein 7. (159 aa)
CYR61Protein CYR61. (286 aa)
HIP1RHuntingtin-interacting protein 1-related protein. (891 aa)
CRADDDeath domain-containing protein CRADD. (197 aa)
IFT57Intraflagellar transport protein 57. (361 aa)
CTSHPro-cathepsin H; Belongs to the peptidase C1 family. (201 aa)
PARK2RBR-type E3 ubiquitin transferase. (409 aa)
TNFSF15Tumor necrosis factor ligand superfamily member 15; Belongs to the tumor necrosis factor family. (229 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (233 aa)
TNIP3TNFAIP3-interacting protein 3. (300 aa)
BBS7Bardet-Biedl syndrome 7 protein. (682 aa)
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats. (1375 aa)
CLPXUncharacterized protein. (607 aa)
AS28_10272Casein kinase I isoform alpha; Belongs to the protein kinase superfamily. (336 aa)
USP13Ubiquitin carboxyl-terminal hydrolase. (801 aa)
HSPD1Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (573 aa)
RNF19ARBR-type E3 ubiquitin transferase. (822 aa)
PLGRKTPlasminogen receptor (KT). (147 aa)
AS28_1362726S protease regulatory subunit 4; Belongs to the AAA ATPase family. (438 aa)
BCL10B-cell lymphoma/leukemia 10. (218 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (477 aa)
SOCS4Suppressor of cytokine signaling 4. (436 aa)
SMAD7Mothers against decapentaplegic 7. (184 aa)
CLUL1Clusterin; Belongs to the clusterin family. (460 aa)
TMEM130Transmembrane protein 130. (408 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (320 aa)
BTRCF-box/WD repeat-containing protein 1A. (593 aa)
SART3Squamous cell carcinoma antigen recognized by T-cells 3. (876 aa)
PIDD1P53-induced protein with a death domain. (885 aa)
AS28_10182Uncharacterized protein. (566 aa)
GCLCGlutamate--cysteine ligase catalytic subunit. (586 aa)
CSNK1ECasein kinase I isoform epsilon. (393 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (999 aa)
ARL6IP5PRA1 family protein. (122 aa)
RESTRE1-silencing transcription factor. (888 aa)
ASTLMetalloendopeptidase. (405 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (122 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (155 aa)
RNF144BRBR-type E3 ubiquitin transferase. (303 aa)
AS28_05455Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B. (433 aa)
RHBDD1Rhomboid-related protein 4. (220 aa)
AXIN1Axin-1. (841 aa)
RNF139E3 ubiquitin-protein ligase RNF139. (603 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (192 aa)
LAPTM5Lysosomal-associated transmembrane protein 5. (219 aa)
AS28_11597Tumor necrosis factor receptor superfamily member 16. (92 aa)
CLN6Ceroid-lipofuscinosis neuronal protein 6. (245 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa)
AS28_12920Receptor-interacting serine/threonine-protein kinase 2. (201 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (253 aa)
PLK1Serine/threonine-protein kinase PLK1. (473 aa)
CASP8AP2CASP8-associated protein 2. (1923 aa)
AGBL4Cytosolic carboxypeptidase 6. (79 aa)
FADDProtein FADD. (153 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (465 aa)
AS28_00351Fragile X mental retardation protein 1 B. (549 aa)
CASP2Caspase-2; Belongs to the peptidase C14A family. (426 aa)
DDA1DET1-and DDB1-associated protein 1. (101 aa)
SGTASmall glutamine-rich tetratricopeptide repeat-containing protein alpha. (302 aa)
AS28_08649Tyrosine-protein kinase. (330 aa)
LYNTyrosine-protein kinase. (513 aa)
AS28_07342Protein PML. (342 aa)
AS28_02302Protein-tyrosine kinase 2-beta. (65 aa)
AS28_01302Protein kinase C and casein kinase substrate in neurons protein 3. (476 aa)
TRIB2Tribbles 2. (343 aa)
LGMNLegumain. (430 aa)
AS28_15150Aspartyl/asparaginyl beta-hydroxylase. (703 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1023 aa)
CLEC3BTetranectin. (157 aa)
CTSDCathepsin D; Belongs to the peptidase A1 family. (381 aa)
ST18Suppression of tumorigenicity 18 protein. (1026 aa)
ZC3H12ARibonuclease ZC3H12A. (481 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1095 aa)
BAG2BAG family molecular chaperone regulator 2. (146 aa)
RNF180E3 ubiquitin-protein ligase RNF180. (592 aa)
FBXW11F-box/WD repeat-containing protein 11. (552 aa)
TMEM259Membralin. (563 aa)
BIDBH3-interacting domain death agonist. (183 aa)
ADRM1Proteasomal ubiquitin receptor ADRM1. (409 aa)
AS28_07109DDRGK domain-containing protein 1. (291 aa)
KLHL40Kelch-like 40. (619 aa)
AKIRIN2Akirin-2. (125 aa)
PRELID1PRELI/MSF1 domain-containing protein. (162 aa)
RNF144ARBR-type E3 ubiquitin transferase. (292 aa)
AS28_03580Rho-associated protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1400 aa)
RNF14RBR-type E3 ubiquitin transferase. (472 aa)
CSNK1DCasein kinase I isoform delta. (385 aa)
USP50Putative ubiquitin carboxyl-terminal hydrolase 50. (273 aa)
CDC20BCell division cycle protein 20 B. (106 aa)
SH3RF1E3 ubiquitin-protein ligase SH3RF1. (869 aa)
FBLN1Fibulin-1. (679 aa)
ARIH2RBR-type E3 ubiquitin transferase. (490 aa)
PMLProtein PML. (295 aa)
FGFR4Receptor protein-tyrosine kinase. (563 aa)
FBXO22F-box only protein 22. (307 aa)
AS28_13250SH3 domain-containing protein 19. (793 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (388 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (361 aa)
AS28_08128TNFAIP3-interacting protein 1. (614 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (411 aa)
NUB1NEDD8 ultimate buster 1. (608 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2444 aa)
TMTC3Transmembrane and TPR repeat-containing protein 3. (919 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (239 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (116 aa)
BAK1Bcl-2 homologous antagonist/killer. (189 aa)
RCHY1RING finger and CHY zinc finger domain-containing protein 1. (155 aa)
PDCD5Programmed cell death protein 5. (104 aa)
AS28_09454Protein zyg-11 B. (736 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (835 aa)
RNF217RBR-type E3 ubiquitin transferase. (249 aa)
ZER1Protein zer-1. (769 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (173 aa)
AURKAIP1Aurora kinase A-interacting protein. (202 aa)
AS28_08394Interleukin-1; Belongs to the IL-1 family. (269 aa)
AS28_05270Metalloendopeptidase. (443 aa)
CAPN3Calpain-3; Belongs to the peptidase C2 family. (794 aa)
DAPDeath-associated protein 1. (86 aa)
SNX9Sorting nexin-9. (597 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1. (602 aa)
AS28_09591Platelet receptor Gi24. (294 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (512 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
DIABLOUncharacterized protein. (223 aa)
GRAMD4GRAM domain-containing protein 4. (595 aa)
PCOLCE2Procollagen C-endopeptidase enhancer 2. (388 aa)
DET1DET1. (544 aa)
AS28_08841Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (221 aa)
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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