(71 nodes) Tyrosine-specific protein phosphatases domain network (Pygoscelis adeliae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTP4A1	Protein tyrosine phosphatase type IVA 1. (173 aa)
	PTPN13	Tyrosine-protein phosphatase non-receptor type 13. (263 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (144 aa)
	EPM2A	Uncharacterized protein. (227 aa)
	MTM1	Myotubularin. (603 aa)
	MTMR7	Myotubularin-related protein 7. (650 aa)
	AS28_04977	Dual specificity phosphatase 28; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (133 aa)
	DUSP1	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type 2. (269 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type 6. (608 aa)
	PTPN7	Tyrosine-protein phosphatase non-receptor type 7. (363 aa)
	MTMR1	Myotubularin-related protein 1. (617 aa)
	AS28_07899	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2. (466 aa)
	DUSP10	Dual specificity protein phosphatase 10. (481 aa)
	FRMPD2	Tyrosine-protein phosphatase non-receptor type 20. (301 aa)
	MTMR2	Myotubularin-related protein 2. (620 aa)
	DUPD1	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (214 aa)
	PTPRS	Receptor-type tyrosine-protein phosphatase S. (1889 aa)
	AS28_10353	Receptor-type tyrosine-protein phosphatase mu. (205 aa)
	DUSP7	Dual specificity protein phosphatase 7. (247 aa)
	MTMR4	Myotubularin-related protein 4. (619 aa)
	CDKN3	Cyclin-dependent kinase inhibitor 3. (209 aa)
	STYX	Serine/threonine/tyrosine-interacting protein. (193 aa)
	DUSP27	Inactive dual specificity phosphatase 27; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1166 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type 11. (315 aa)
	PTP4A2	Protein tyrosine phosphatase type IVA 2. (170 aa)
	DUSP6	Dual specificity protein phosphatase 6. (248 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type 1. (417 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C. (1212 aa)
	AS28_08261	Receptor-type tyrosine-protein phosphatase V. (1038 aa)
	PTPN4	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (929 aa)
	DUSP11	RNA/RNP complex-1-interacting phosphatase. (169 aa)
	DUSP16	Dual specificity protein phosphatase 16. (664 aa)
	CDC14B	Dual specificity protein phosphatase CDC14A. (352 aa)
	PTPRQ	Phosphatidylinositol phosphatase PTPRQ. (2319 aa)
	PTPRB	Receptor-type tyrosine-protein phosphatase beta. (1929 aa)
	SSH2	Protein phosphatase Slingshot 2. (1370 aa)
	AS28_12226	Receptor-type tyrosine-protein phosphatase-like N. (252 aa)
	DUSP5	Dual specificity protein phosphatase 5; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (244 aa)
	AS28_12843	Receptor-type tyrosine-protein phosphatase kappa. (368 aa)
	DUSP19	Dual specificity protein phosphatase 19. (141 aa)
	PTPRN2	Receptor-type tyrosine-protein phosphatase N2. (325 aa)
	PTPN14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1189 aa)
	DUSP15	Dual specificity protein phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (209 aa)
	PTPRR	Receptor-type tyrosine-protein phosphatase R. (542 aa)
	AS28_08691	Tyrosine-protein phosphatase non-receptor type 11. (420 aa)
	PTPN22	Tyrosine-protein phosphatase non-receptor type 22. (307 aa)
	PTP4A3	Protein tyrosine phosphatase type IVA 3. (175 aa)
	PTPN5	Tyrosine-protein phosphatase non-receptor type 5. (532 aa)
	PTPDC1	Protein tyrosine phosphatase domain-containing protein 1. (778 aa)
	AS28_06433	Serine/threonine/tyrosine-interacting-like 1. (297 aa)
	PTEN	annotation not available (376 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12. (268 aa)
	PTPRA	Receptor-type tyrosine-protein phosphatase alpha. (807 aa)
	DUSP4	Dual specificity protein phosphatase 4; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (247 aa)
	RNGTT	mRNA-capping enzyme. (579 aa)
	AS28_14776	Receptor-type tyrosine-protein phosphatase zeta. (2270 aa)
	AS28_01351	Tensin-3. (1440 aa)
	PTPRF	Receptor-type tyrosine-protein phosphatase F. (1863 aa)
	AS28_00180	Dual specificity protein phosphatase CDC14A. (569 aa)
	SSH1	Protein phosphatase Slingshot 1. (1049 aa)
	PTPRT	Receptor-type tyrosine-protein phosphatase T. (1390 aa)
	PTPN21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1166 aa)
	AS28_05964	Dual specificity protein phosphatase 13 isoform B; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (282 aa)
	PALD1	Paladin. (855 aa)
	AS28_09674	Receptor-type tyrosine-protein phosphatase epsilon. (641 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta. (973 aa)
	PTPMT1	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1. (135 aa)
	AS28_12844	Receptor-type tyrosine-protein phosphatase alpha. (91 aa)
	PTPN3	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (919 aa)
	PTPRO	Receptor-type tyrosine-protein phosphatase O. (1193 aa)

Your Current Organism:

Pygoscelis adeliae

NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AS28_00180	CDC14B	A0A093QTY1	A0A093NZ30	Dual specificity protein phosphatase CDC14A.	Dual specificity protein phosphatase CDC14A.	0.935
AS28_01351	PTPMT1	A0A093PLB1	A0A093RJP1	Tensin-3.	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1.	0.410
AS28_04977	DUPD1	A0A093NGB8	A0A093NMI7	Dual specificity phosphatase 28; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.413
AS28_05964	EPM2A	A0A093R4N7	A0A093NAZ2	Dual specificity protein phosphatase 13 isoform B; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Uncharacterized protein.	0.418
AS28_08691	PTPN11	A0A093P6M0	A0A093NR31	Tyrosine-protein phosphatase non-receptor type 11.	Tyrosine-protein phosphatase non-receptor type 11.	0.902
AS28_08691	PTPN6	A0A093P6M0	A0A093NHV2	Tyrosine-protein phosphatase non-receptor type 11.	Tyrosine-protein phosphatase non-receptor type 6.	0.460
AS28_12843	AS28_12844	A0A093P3W1	A0A093RL96	Receptor-type tyrosine-protein phosphatase kappa.	Receptor-type tyrosine-protein phosphatase alpha.	0.657
AS28_12844	AS28_12843	A0A093RL96	A0A093P3W1	Receptor-type tyrosine-protein phosphatase alpha.	Receptor-type tyrosine-protein phosphatase kappa.	0.657
CDC14B	AS28_00180	A0A093NZ30	A0A093QTY1	Dual specificity protein phosphatase CDC14A.	Dual specificity protein phosphatase CDC14A.	0.935
DUPD1	AS28_04977	A0A093NMI7	A0A093NGB8	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity phosphatase 28; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.413
DUSP3	PTPN5	A0A093N8W4	A0A093P7R7	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type 5.	0.905
DUSP3	PTPN7	A0A093N8W4	A0A093NIC7	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type 7.	0.922
DUSP3	PTPRR	A0A093N8W4	A0A093P5T5	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Receptor-type tyrosine-protein phosphatase R.	0.907
EPM2A	AS28_05964	A0A093NAZ2	A0A093R4N7	Uncharacterized protein.	Dual specificity protein phosphatase 13 isoform B; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.418
MTMR4	RNGTT	A0A093NPS6	A0A093PGY7	Myotubularin-related protein 4.	mRNA-capping enzyme.	0.481
PTPMT1	AS28_01351	A0A093RJP1	A0A093PLB1	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1.	Tensin-3.	0.410
PTPN11	AS28_08691	A0A093NR31	A0A093P6M0	Tyrosine-protein phosphatase non-receptor type 11.	Tyrosine-protein phosphatase non-receptor type 11.	0.902
PTPN11	PTPN6	A0A093NR31	A0A093NHV2	Tyrosine-protein phosphatase non-receptor type 11.	Tyrosine-protein phosphatase non-receptor type 6.	0.458
PTPN5	DUSP3	A0A093P7R7	A0A093N8W4	Tyrosine-protein phosphatase non-receptor type 5.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.905
PTPN5	PTPN7	A0A093P7R7	A0A093NIC7	Tyrosine-protein phosphatase non-receptor type 5.	Tyrosine-protein phosphatase non-receptor type 7.	0.930