52 items (Pygoscelis adeliae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RNF185	E3 ubiquitin-protein ligase RNF185. (194 aa)
	UBB	Polyubiquitin. (290 aa)
	KCNJ11	ATP-sensitive inward rectifier potassium channel 11. (359 aa)
	PSMA7	Proteasome endopeptidase complex. (216 aa)
	ABCC9	ATP-binding cassette sub-family C member 9. (1562 aa)
	ABCG5	ATP-binding cassette sub-family G member 5. (646 aa)
	AS28_11318	Multidrug resistance-associated protein 5. (1435 aa)
	ABCD2	ATP-binding cassette sub-family D member 2. (679 aa)
	ABCB7	Uncharacterized protein. (671 aa)
	LRP2BP	LRP2-binding protein. (273 aa)
	ABCA13	ATP-binding cassette sub-family A member 13. (620 aa)
	ABCA12	ATP-binding cassette sub-family A member 12. (2605 aa)
	ABCG4	ATP-binding cassette sub-family G member 4. (654 aa)
	AS28_13785	ATP-binding cassette sub-family A member 9. (243 aa)
	ABCB10	Uncharacterized protein. (587 aa)
	DERL1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (201 aa)
	ABCC2	Canalicular multispecific organic anion transporter 1. (1543 aa)
	PTCHD3	Patched domain-containing protein 3. (659 aa)
	AS28_14511	Multidrug resistance-associated protein 6. (1488 aa)
	PTCHD1	Patched domain-containing protein 1. (770 aa)
	AS28_13783	ATP-binding cassette sub-family A member 5. (190 aa)
	AS28_14623	Uncharacterized protein. (122 aa)
	AS28_12315	ATP-binding cassette sub-family A member 2. (2284 aa)
	ABCB6	Uncharacterized protein. (549 aa)
	PLEKHD1	Pleckstrin homology domain-containing family D member 1. (381 aa)
	ABCC4	Multidrug resistance-associated protein 4. (1307 aa)
	ABCG8	ATP-binding cassette sub-family G member 8. (654 aa)
	AS28_13784	ATP-binding cassette sub-family A member 10. (202 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1474 aa)
	ABCC3	Canalicular multispecific organic anion transporter 2. (1515 aa)
	ABCD3	ATP-binding cassette sub-family D member 3. (621 aa)
	AS28_13786	ATP-binding cassette sub-family A member 9. (277 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1. (951 aa)
	AS28_13627	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (438 aa)
	PEX3	Peroxisomal biogenesis factor 3. (345 aa)
	ABCB9	ATP-binding cassette sub-family B member 9. (546 aa)
	EIF2S3	Eukaryotic translation initiation factor 2 subunit 3. (429 aa)
	SEL1L	Protein sel-1 1. (770 aa)
	ERLIN2	Erlin-2. (282 aa)
	PTCHD4	Patched domain-containing protein 4. (887 aa)
	RPS27A	Ubiquitin-40S ribosomal protein S27a. (141 aa)
	KIAA0141	Death ligand signal enhancer. (200 aa)
	DERL3	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (211 aa)
	ABCF3	ATP-binding cassette sub-family F member 3. (611 aa)
	DERL2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (208 aa)
	SEL1L3	Protein sel-1 3. (1030 aa)
	PSMA1	Proteasome endopeptidase complex. (246 aa)
	ABCA5	ATP-binding cassette sub-family A member 5. (1648 aa)
	ABCC1	Multidrug resistance-associated protein 1. (1509 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10. (155 aa)
	VCP	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (802 aa)
	AS28_14106	Uncharacterized protein. (97 aa)

Your Current Organism:

Pygoscelis adeliae

NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA12	ABCA13	A0A093P3U2	A0A093P3Z6	ATP-binding cassette sub-family A member 12.	ATP-binding cassette sub-family A member 13.	0.609
ABCA13	ABCA12	A0A093P3Z6	A0A093P3U2	ATP-binding cassette sub-family A member 13.	ATP-binding cassette sub-family A member 12.	0.609
ABCA13	ABCA5	A0A093P3Z6	A0A093R730	ATP-binding cassette sub-family A member 13.	ATP-binding cassette sub-family A member 5.	0.533
ABCA13	AS28_13786	A0A093P3Z6	A0A093NPV2	ATP-binding cassette sub-family A member 13.	ATP-binding cassette sub-family A member 9.	0.613
ABCA5	ABCA13	A0A093R730	A0A093P3Z6	ATP-binding cassette sub-family A member 5.	ATP-binding cassette sub-family A member 13.	0.533
ABCB10	ABCB6	A0A093P2V9	A0A093NU52	Uncharacterized protein.	Uncharacterized protein.	0.411
ABCB10	ABCB7	A0A093P2V9	A0A093P4P1	Uncharacterized protein.	Uncharacterized protein.	0.677
ABCB10	ABCF3	A0A093P2V9	A0A093PJ55	Uncharacterized protein.	ATP-binding cassette sub-family F member 3.	0.432
ABCB10	ABCG5	A0A093P2V9	A0A093P6V7	Uncharacterized protein.	ATP-binding cassette sub-family G member 5.	0.409
ABCB6	ABCB10	A0A093NU52	A0A093P2V9	Uncharacterized protein.	Uncharacterized protein.	0.411
ABCB6	ABCB9	A0A093NU52	A0A093NM11	Uncharacterized protein.	ATP-binding cassette sub-family B member 9.	0.411
ABCB6	ABCF3	A0A093NU52	A0A093PJ55	Uncharacterized protein.	ATP-binding cassette sub-family F member 3.	0.493
ABCB7	ABCB10	A0A093P4P1	A0A093P2V9	Uncharacterized protein.	Uncharacterized protein.	0.677
ABCB7	ABCB9	A0A093P4P1	A0A093NM11	Uncharacterized protein.	ATP-binding cassette sub-family B member 9.	0.608
ABCB7	ABCF3	A0A093P4P1	A0A093PJ55	Uncharacterized protein.	ATP-binding cassette sub-family F member 3.	0.591
ABCB9	ABCB6	A0A093NM11	A0A093NU52	ATP-binding cassette sub-family B member 9.	Uncharacterized protein.	0.411
ABCB9	ABCB7	A0A093NM11	A0A093P4P1	ATP-binding cassette sub-family B member 9.	Uncharacterized protein.	0.608
ABCB9	ABCG5	A0A093NM11	A0A093P6V7	ATP-binding cassette sub-family B member 9.	ATP-binding cassette sub-family G member 5.	0.409
ABCC1	DERL1	A0A093R9B6	A0A093P2U7	Multidrug resistance-associated protein 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.407
ABCC1	RNF185	A0A093R9B6	A0A093RM00	Multidrug resistance-associated protein 1.	E3 ubiquitin-protein ligase RNF185.	0.415