STRINGSTRING
AS28_09798 AS28_09798 SOD2 SOD2 MED1 MED1 HELZ2 HELZ2 ATF4 ATF4 PSMB4 PSMB4 PSMF1 PSMF1 GSK3B GSK3B AS28_14591 AS28_14591 PSMA5 PSMA5 AS28_08383 AS28_08383 PSMB7 PSMB7 AS28_14723 AS28_14723 SIN3B SIN3B RPS27A RPS27A PSME3 PSME3 AS28_08398 AS28_08398 BACH2 BACH2 AKT3 AKT3 AS28_08382 AS28_08382 AS28_09920 AS28_09920 TXNRD2 TXNRD2 CAT CAT PSMA2 PSMA2 BLVRA BLVRA RBX1 RBX1 DESI1 DESI1 RXRA RXRA DESI2 DESI2 TBL1XR1 TBL1XR1 SKP1 SKP1 ERO1L ERO1L CUL1 CUL1 AS28_13627 AS28_13627 PSMD1 PSMD1 AS28_08384 AS28_08384 MAFK MAFK BTRC BTRC GPX7 GPX7 P4HB P4HB PPARA PPARA NOX4 NOX4 AS28_13845 AS28_13845 SESN3 SESN3 AS28_02628 AS28_02628 AS28_15047 AS28_15047 PSMD9 PSMD9 PSMD14 PSMD14 NCF2 NCF2 AS28_14877 AS28_14877 NPVF NPVF PRDX3 PRDX3 AS28_08450 AS28_08450 SOD3 SOD3 PRDX1 PRDX1 PSMD7 PSMD7 AS28_11179 AS28_11179 CARM1 CARM1 HMOX2 HMOX2 SOD1 SOD1 PSMD5 PSMD5 KLHL17 KLHL17 PSMB2 PSMB2 PSMC2 PSMC2 GSAP GSAP SQSTM1 SQSTM1 PSMD6 PSMD6 UBXN7 UBXN7 PSMC6 PSMC6 NFE2L3 NFE2L3 MAP1LC3B MAP1LC3B PSMC3 PSMC3 TXN TXN FAM45A FAM45A TXNRD3 TXNRD3 PSMA4 PSMA4 SKP2 SKP2 SESN2 SESN2 AS28_11439 AS28_11439 PSMD11 PSMD11 AS28_08544 AS28_08544 AS28_14453 AS28_14453 BACH1 BACH1 PSMA3 PSMA3 NUDT2 NUDT2 NCOR1 NCOR1 AS28_13479 AS28_13479 AS28_15128 AS28_15128 PSMB1 PSMB1 AS28_09505 AS28_09505 NCF4 NCF4 PSMA7 PSMA7 NFE2L1 NFE2L1 AS28_02531 AS28_02531 UBB UBB AS28_14177 AS28_14177 PSMA1 PSMA1 AS28_09221 AS28_09221 SPPL3 SPPL3 UFD1L UFD1L AKT1 AKT1 AS28_00819 AS28_00819 AS28_08381 AS28_08381 NCF1 NCF1 PSMA6 PSMA6 SURF1 SURF1 AS28_11487 AS28_11487 AS28_03908 AS28_03908 PSMD12 PSMD12 AS28_14455 AS28_14455 AS28_07757 AS28_07757 CUL3 CUL3 LRPPRC LRPPRC PSMB3 PSMB3 AS28_05455 AS28_05455 GPX8 GPX8 PSMD10 PSMD10 AS28_03183 AS28_03183 AS28_14014 AS28_14014 SMARCD3 SMARCD3 VCP VCP FABP1 FABP1 AS28_04090 AS28_04090 HMOX1 HMOX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AS28_09798Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (511 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (215 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1574 aa)
HELZ2Helicase with zinc finger domain 2. (2557 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (355 aa)
PSMB4Proteasome subunit beta. (206 aa)
PSMF1Proteasome inhibitor PI31 subunit. (229 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (371 aa)
AS28_14591Uncharacterized protein. (118 aa)
PSMA5Proteasome endopeptidase complex. (165 aa)
AS28_08383Hemoglobin subunit beta; Belongs to the globin family. (116 aa)
PSMB7Proteasome subunit beta type-7. (225 aa)
AS28_14723Nuclear protein localization protein 4. (555 aa)
SIN3BPaired amphipathic helix protein Sin3b. (1082 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (141 aa)
PSME3Proteasome activator complex subunit 3. (242 aa)
AS28_08398Nuclear receptor corepressor 2. (699 aa)
BACH2Transcription regulator protein BACH2. (824 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (464 aa)
AS28_08382Hemoglobin subunit beta; Belongs to the globin family. (147 aa)
AS28_09920Peroxiredoxin-6. (191 aa)
TXNRD2Uncharacterized protein. (490 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (507 aa)
PSMA2Proteasome endopeptidase complex. (226 aa)
BLVRABiliverdin reductase A. (300 aa)
RBX1RING-box protein 1. (78 aa)
DESI1Desumoylating isopeptidase 1. (142 aa)
RXRARetinoic acid receptor RXR-alpha. (458 aa)
DESI2Desumoylating isopeptidase 2. (180 aa)
TBL1XR1F-box-like/WD repeat-containing protein TBL1XR1. (489 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
ERO1LERO1-like alpha. (428 aa)
CUL1Cullin-1; Belongs to the cullin family. (791 aa)
AS28_1362726S protease regulatory subunit 4; Belongs to the AAA ATPase family. (438 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1. (951 aa)
AS28_08384Hemoglobin subunit epsilon; Belongs to the globin family. (147 aa)
MAFKTranscription factor MafK. (156 aa)
BTRCF-box/WD repeat-containing protein 1A. (593 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (167 aa)
P4HBProtein disulfide-isomerase. (459 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (470 aa)
NOX4NADPH oxidase 4. (563 aa)
AS28_13845Uncharacterized protein. (102 aa)
SESN3Sestrin-3. (466 aa)
AS28_02628Cytochrome c oxidase subunit 6C. (57 aa)
AS28_15047Uncharacterized protein. (92 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (136 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
NCF2Neutrophil cytosol factor 2. (503 aa)
AS28_14877Cytochrome b-245 heavy chain. (570 aa)
NPVFGonadotropin inhibitory hormone peptides. (173 aa)
PRDX3Thioredoxin domain-containing protein. (172 aa)
AS28_08450Desumoylating isopeptidase 2. (183 aa)
SOD3Extracellular superoxide dismutase [Cu-Zn]. (172 aa)
PRDX1Peroxiredoxin-1. (201 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (298 aa)
AS28_11179Cytochrome c oxidase protein 20. (107 aa)
CARM1Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (395 aa)
HMOX2Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (312 aa)
SOD1Superoxide dismutase [Cu-Zn]. (132 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (447 aa)
KLHL17Kelch-like 17. (602 aa)
PSMB2Proteasome subunit beta. (171 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (411 aa)
GSAPGamma-secretase-activating protein. (820 aa)
SQSTM1Sequestosome-1. (398 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (343 aa)
UBXN7UBX domain-containing protein 7. (468 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (361 aa)
NFE2L3Nuclear factor erythroid 2-related factor 3; Belongs to the bZIP family. (301 aa)
MAP1LC3BMicrotubule-associated proteins 1A/1B light chain 3B. (111 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (388 aa)
TXNThioredoxin. (96 aa)
FAM45AProtein FAM45A. (343 aa)
TXNRD3Thioredoxin reductase 3. (487 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
SKP2S-phase kinase-associated protein 2. (419 aa)
SESN2Sestrin-2. (133 aa)
AS28_11439Thioredoxin domain-containing protein 6. (82 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (392 aa)
AS28_08544Cytochrome c oxidase subunit 6A, mitochondrial. (73 aa)
AS28_14453Hemoglobin subunit alpha; Belongs to the globin family. (142 aa)
BACH1Transcription regulator protein BACH1. (759 aa)
PSMA3Proteasome subunit alpha type. (234 aa)
NUDT2Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]. (148 aa)
NCOR1Nuclear receptor corepressor 1. (2473 aa)
AS28_1347926S proteasome non-ATPase regulatory subunit 4. (284 aa)
AS28_15128Trimethylguanosine synthase. (830 aa)
PSMB1Proteasome subunit beta. (203 aa)
AS28_09505Thioredoxin domain-containing protein. (117 aa)
NCF4Neutrophil cytosol factor 4. (349 aa)
PSMA7Proteasome endopeptidase complex. (216 aa)
NFE2L1Nuclear factor erythroid 2-related factor 1; Belongs to the bZIP family. (339 aa)
AS28_02531Uncharacterized protein. (68 aa)
UBBPolyubiquitin. (290 aa)
AS28_14177Sestrin-3. (430 aa)
PSMA1Proteasome endopeptidase complex. (246 aa)
AS28_09221Uncharacterized protein. (38 aa)
SPPL3Signal peptide peptidase-like 3. (378 aa)
UFD1LUbiquitin fusion degradation protein 1. (306 aa)
AKT1RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (465 aa)
AS28_00819Uncharacterized protein. (176 aa)
AS28_08381Hemoglobin subunit rho; Belongs to the globin family. (147 aa)
NCF1Neutrophil cytosol factor 1. (389 aa)
PSMA6Proteasome endopeptidase complex. (222 aa)
SURF1SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (288 aa)
AS28_11487Uncharacterized protein. (148 aa)
AS28_03908Cytochrome c oxidase subunit 6C. (67 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (420 aa)
AS28_14455Hemoglobin subunit pi; Belongs to the globin family. (142 aa)
AS28_07757Mitochondrial inner membrane protein COX18. (204 aa)
CUL3Cullin-3; Belongs to the cullin family. (746 aa)
LRPPRCUncharacterized protein. (1342 aa)
PSMB3Proteasome subunit beta type-3. (151 aa)
AS28_05455Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (155 aa)
AS28_03183F-box/LRR-repeat protein 17. (328 aa)
AS28_14014Uncharacterized protein C1orf198. (203 aa)
SMARCD3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (377 aa)
VCPTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (802 aa)
FABP1Fatty acid-binding protein, liver. (127 aa)
AS28_04090Uncharacterized protein. (147 aa)
HMOX1Heme oxygenase 1. (278 aa)
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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