77 items (Pygoscelis adeliae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (491 aa)
	AS28_12481	Vacuolar protein sorting-associated protein 4B. (149 aa)
	NAV3	Neuron navigator 3. (2385 aa)
	AS28_03141	ATP-binding cassette sub-family G member 2. (594 aa)
	AS28_08252	Neuron navigator 1. (1520 aa)
	LONP1	Uncharacterized protein. (699 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (467 aa)
	ABCC8	ATP-binding cassette sub-family C member 8. (1516 aa)
	ORC1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa)
	VWA8	Von Willebrand factor A domain-containing protein 8. (1830 aa)
	AS28_12315	ATP-binding cassette sub-family A member 2. (2284 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	ABCC4	Multidrug resistance-associated protein 4. (1307 aa)
	ABCB11	Bile salt export pump. (1281 aa)
	MCM2	DNA helicase; Belongs to the MCM family. (886 aa)
	PEX6	Peroxisome assembly factor 2; Belongs to the AAA ATPase family. (673 aa)
	SPAST	Spastin; Belongs to the AAA ATPase family. (478 aa)
	ABCG5	ATP-binding cassette sub-family G member 5. (646 aa)
	ABCC9	ATP-binding cassette sub-family C member 9. (1562 aa)
	RFC1	Replication factor C subunit 1. (1158 aa)
	DHX37	Putative ATP-dependent RNA helicase DHX37. (1111 aa)
	IQCA1	IQ and AAA domain-containing protein 1. (777 aa)
	ASCC3	Activating signal cointegrator 1 complex subunit 3. (1993 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1474 aa)
	MCM3	DNA helicase; Belongs to the MCM family. (779 aa)
	ABCC3	Canalicular multispecific organic anion transporter 2. (1515 aa)
	ATAD5	ATPase family AAA domain-containing protein 5. (1778 aa)
	ABCD3	ATP-binding cassette sub-family D member 3. (621 aa)
	AS28_13627	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (438 aa)
	NVL	Nuclear valosin-containing protein-like. (803 aa)
	TOR2A	Torsin-2A. (267 aa)
	DNAH7	Dynein heavy chain 7, axonemal. (3496 aa)
	CLPX	Uncharacterized protein. (607 aa)
	ABCB9	ATP-binding cassette sub-family B member 9. (546 aa)
	IGHMBP2	DNA-binding protein SMUBP-2. (958 aa)
	LONP2	Lon protease homolog; Belongs to the peptidase S16 family. (775 aa)
	SPG7	Paraplegin. (739 aa)
	AFG3L2	AFG3-like 2. (767 aa)
	ATAD2B	ATPase family AAA domain-containing protein 2B. (968 aa)
	AS28_14511	Multidrug resistance-associated protein 6. (1488 aa)
	ABCD4	ATP-binding cassette sub-family D member 4. (591 aa)
	RFC2	Replication factor C subunit 2. (316 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	NAV2	Neuron navigator 2. (2312 aa)
	ATAD1	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (363 aa)
	FIGNL1	Fidgetin-like 1; Belongs to the AAA ATPase family. (691 aa)
	ABCF3	ATP-binding cassette sub-family F member 3. (611 aa)
	MCM4	DNA helicase; Belongs to the MCM family. (784 aa)
	RUVBL1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (409 aa)
	DNAH12	Dynein heavy chain 7, axonemal. (3864 aa)
	ABCA5	ATP-binding cassette sub-family A member 5. (1648 aa)
	ABCC1	Multidrug resistance-associated protein 1. (1509 aa)
	AS28_08277	Mitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (420 aa)
	FIGN	Fidgetin; Belongs to the AAA ATPase family. (751 aa)
	MCM9	DNA helicase MCM9; Belongs to the MCM family. (1048 aa)
	RFC3	Replication factor C subunit 3. (327 aa)
	KATNA1-2	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily. (487 aa)
	NSF	Vesicle-fusing ATPase. (719 aa)
	YME1L1	ATP-dependent zinc metalloprotease YME1L1. (714 aa)
	AS28_11229	Chromosome transmission fidelity protein 18. (231 aa)
	VCP	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (802 aa)
	DMC1	Meiotic recombination protein DMC1/LIM15; Belongs to the RecA family. (346 aa)
	PSMC2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (411 aa)
	ATAD3A	ATPase family AAA domain-containing protein 3-A. (530 aa)
	PSMC6	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (361 aa)
	PSMC3	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (388 aa)
	ABCC2	Canalicular multispecific organic anion transporter 1. (1543 aa)
	ABCB10	Uncharacterized protein. (587 aa)
	ABCG4	ATP-binding cassette sub-family G member 4. (654 aa)
	ABCA12	ATP-binding cassette sub-family A member 12. (2605 aa)
	PEX1	Peroxisome biogenesis factor 1. (1250 aa)
	ABCB7	Uncharacterized protein. (671 aa)
	MCM8	DNA helicase MCM8; Belongs to the MCM family. (818 aa)
	ABCD2	ATP-binding cassette sub-family D member 2. (679 aa)
	ABCF2	ATP-binding cassette sub-family F member 2. (576 aa)
	TRIP13	Pachytene checkpoint protein 2; Belongs to the AAA ATPase family. (409 aa)
	AS28_11318	Multidrug resistance-associated protein 5. (1435 aa)

Your Current Organism:

Pygoscelis adeliae

NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA5	ABCD4	A0A093R730	A0A093NG72	ATP-binding cassette sub-family A member 5.	ATP-binding cassette sub-family D member 4.	0.404
ABCB10	ABCB11	A0A093P2V9	A0A093NTD8	Uncharacterized protein.	Bile salt export pump.	0.401
ABCB10	ABCB7	A0A093P2V9	A0A093P4P1	Uncharacterized protein.	Uncharacterized protein.	0.677
ABCB10	ABCF3	A0A093P2V9	A0A093PJ55	Uncharacterized protein.	ATP-binding cassette sub-family F member 3.	0.432
ABCB10	ABCG5	A0A093P2V9	A0A093P6V7	Uncharacterized protein.	ATP-binding cassette sub-family G member 5.	0.409
ABCB10	KATNAL2	A0A093P2V9	A0A093NWI0	Uncharacterized protein.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.559
ABCB11	ABCB10	A0A093NTD8	A0A093P2V9	Bile salt export pump.	Uncharacterized protein.	0.401
ABCB11	ABCB7	A0A093NTD8	A0A093P4P1	Bile salt export pump.	Uncharacterized protein.	0.496
ABCB11	ABCB9	A0A093NTD8	A0A093NM11	Bile salt export pump.	ATP-binding cassette sub-family B member 9.	0.401
ABCB11	ABCF2	A0A093NTD8	A0A093P518	Bile salt export pump.	ATP-binding cassette sub-family F member 2.	0.426
ABCB11	ABCG5	A0A093NTD8	A0A093P6V7	Bile salt export pump.	ATP-binding cassette sub-family G member 5.	0.400
ABCB11	KATNAL2	A0A093NTD8	A0A093NWI0	Bile salt export pump.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.557
ABCB11	VCP	A0A093NTD8	A0A093RL77	Bile salt export pump.	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	0.570
ABCB7	ABCB10	A0A093P4P1	A0A093P2V9	Uncharacterized protein.	Uncharacterized protein.	0.677
ABCB7	ABCB11	A0A093P4P1	A0A093NTD8	Uncharacterized protein.	Bile salt export pump.	0.496
ABCB7	ABCB9	A0A093P4P1	A0A093NM11	Uncharacterized protein.	ATP-binding cassette sub-family B member 9.	0.608
ABCB7	ABCF2	A0A093P4P1	A0A093P518	Uncharacterized protein.	ATP-binding cassette sub-family F member 2.	0.547
ABCB7	ABCF3	A0A093P4P1	A0A093PJ55	Uncharacterized protein.	ATP-binding cassette sub-family F member 3.	0.591
ABCB9	ABCB11	A0A093NM11	A0A093NTD8	ATP-binding cassette sub-family B member 9.	Bile salt export pump.	0.401
ABCB9	ABCB7	A0A093NM11	A0A093P4P1	ATP-binding cassette sub-family B member 9.	Uncharacterized protein.	0.608