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N300_12501 N300_12501 N300_13823 N300_13823 N300_08968 N300_08968 N300_11002 N300_11002 N300_02138 N300_02138 N300_13086 N300_13086 N300_14734 N300_14734 N300_09241 N300_09241 N300_03125 N300_03125 N300_01821 N300_01821 N300_02424 N300_02424 N300_13006 N300_13006 N300_02595 N300_02595
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
N300_12501Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
N300_13823Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
N300_08968Fibroblast growth factor receptor. (829 aa)
N300_11002Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
N300_02138Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (100 aa)
N300_13086Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
N300_14734Fibroblast growth factor receptor substrate 2. (508 aa)
N300_09241Tyrosine-protein kinase receptor. (748 aa)
N300_03125Fibroblast growth factor receptor 1. (736 aa)
N300_01821Fibroblast growth factor receptor 3. (763 aa)
N300_02424Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (111 aa)
N300_13006Fibroblast growth factor receptor 4. (686 aa)
N300_02595Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (238 aa)
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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