70 items (Calypte anna) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	N300_12430	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (410 aa)
	N300_08644	Phenylalanine-4-hydroxylase. (434 aa)
	N300_09105	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (455 aa)
	N300_07356	Dihydropteridine reductase. (65 aa)
	N300_00661	Uncharacterized protein. (472 aa)
	N300_10317	D-amino-acid oxidase. (340 aa)
	N300_11528	Aminotran_1_2 domain-containing protein. (429 aa)
	N300_01974	Arginase. (293 aa)
	N300_12089	Cystathionine beta-synthase. (165 aa)
	KMO	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (475 aa)
	N300_14871	Fe-ADH domain-containing protein. (419 aa)
	N300_05625	Maleylacetoacetate isomerase. (210 aa)
	N300_07029	D-aspartate oxidase. (341 aa)
	N300_10934	Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
	N300_08895	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (485 aa)
	N300_05655	Lipoyl-binding domain-containing protein. (439 aa)
	N300_05669	Aldedh domain-containing protein. (434 aa)
	N300_12536	Aspartate aminotransferase. (372 aa)
	N300_15391	Protein-serine/threonine kinase. (220 aa)
	N300_01450	Arylacetamide deacetylase-like 4. (251 aa)
	N300_00844	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1. (186 aa)
	N300_06669	Histidine ammonia-lyase; Belongs to the PAL/histidase family. (662 aa)
	N300_13781	Fumarylacetoacetase. (421 aa)
	N300_09732	Aldehyde dehydrogenase family 8 member A1; Belongs to the aldehyde dehydrogenase family. (488 aa)
	N300_13810	Histidine decarboxylase. (655 aa)
	N300_07096	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
	N300_00913	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
	N300_04856	Uncharacterized protein. (391 aa)
	N300_01449	Arylacetamide deacetylase-like 4. (322 aa)
	N300_00364	Uncharacterized protein. (928 aa)
	N300_06448	Glutamate decarboxylase 2. (491 aa)
	N300_03414	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (105 aa)
	N300_12551	ETF domain-containing protein. (313 aa)
	N300_03007	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (337 aa)
	N300_03030	Kynureninase. (467 aa)
	N300_07390	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (479 aa)
	N300_03521	Bleomycin hydrolase. (451 aa)
	TDO2	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
	N300_01078	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (306 aa)
	N300_01193	3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic. (307 aa)
	N300_05093	Kynurenine formamidase. (244 aa)
	N300_12750	Uncharacterized protein. (499 aa)
	N300_11626	Amine oxidase. (484 aa)
	N300_11405	3-hydroxyanthranilate 3,4-dioxygenase. (285 aa)
	N300_11268	Epimerase domain-containing protein. (238 aa)
	N300_06017	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (542 aa)
	N300_15527	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (936 aa)
	N300_01113	Transket_pyr domain-containing protein. (322 aa)
	N300_10829	Pyruvate carboxyltransferase domain-containing protein. (301 aa)
	N300_12757	Cysteine dioxygenase. (137 aa)
	N300_08800	Uncharacterized protein. (895 aa)
	N300_13544	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (375 aa)
	N300_13590	Homogentisate 1,2-dioxygenase. (431 aa)
	N300_10272	4-hydroxyphenylpyruvate dioxygenase. (390 aa)
	N300_14843	Serine dehydratase-like. (171 aa)
	N300_12393	Formimidoyltransferase-cyclodeaminase. (539 aa)
	N300_04563	Glutamate decarboxylase 1. (493 aa)
	N300_00700	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (454 aa)
	N300_07039	Aspartate aminotransferase. (401 aa)
	N300_12091	Cystathionine beta-synthase. (89 aa)
	N300_15353	Phenylserine dehydratase. (438 aa)
	N300_10666	Uncharacterized protein. (376 aa)
	N300_11681	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (369 aa)
	N300_04257	Nitric oxide synthase, inducible. (1141 aa)
	N300_06668	Putative imidazolonepropionase. (386 aa)
	N300_03875	Alanine aminotransferase 2. (538 aa)
	N300_07829	Isoaspartyl peptidase/L-asparaginase. (317 aa)
	N300_01276	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	N300_02799	Methionine synthase reductase. (702 aa)
	N300_15264	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KMO	N300_00700	A0A091HM18	A0A091IBJ3	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.864
KMO	N300_01449	A0A091HM18	A0A091HUV6	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Arylacetamide deacetylase-like 4.	0.708
KMO	N300_01450	A0A091HM18	A0A091HRK8	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Arylacetamide deacetylase-like 4.	0.708
KMO	N300_03007	A0A091HM18	A0A091HY74	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	0.768
KMO	N300_03030	A0A091HM18	A0A091HY95	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynureninase.	0.992
KMO	N300_03875	A0A091HM18	A0A091IGM0	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Alanine aminotransferase 2.	0.630
KMO	N300_04856	A0A091HM18	A0A091HUI4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.402
KMO	N300_05093	A0A091HM18	A0A091I268	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynurenine formamidase.	0.921
KMO	N300_06017	A0A091HM18	A0A091J9S7	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.594
KMO	N300_06669	A0A091HM18	A0A091HSE1	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Histidine ammonia-lyase; Belongs to the PAL/histidase family.	0.508
KMO	N300_07029	A0A091HM18	A0A091HN87	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	D-aspartate oxidase.	0.520
KMO	N300_09105	A0A091HM18	A0A091HH25	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.669
KMO	N300_09732	A0A091HM18	A0A091IMY0	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aldehyde dehydrogenase family 8 member A1; Belongs to the aldehyde dehydrogenase family.	0.710
KMO	N300_10272	A0A091HM18	A0A091I7Q0	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	4-hydroxyphenylpyruvate dioxygenase.	0.610
KMO	N300_10317	A0A091HM18	A0A091HL40	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	D-amino-acid oxidase.	0.520
KMO	N300_10666	A0A091HM18	A0A091IDD9	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.402
KMO	N300_11268	A0A091HM18	A0A091I368	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Epimerase domain-containing protein.	0.413
KMO	N300_11405	A0A091HM18	A0A091I346	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	3-hydroxyanthranilate 3,4-dioxygenase.	0.839
KMO	N300_11528	A0A091HM18	A0A091HLJ0	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.557
KMO	N300_12089	A0A091HM18	A0A091HM08	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Cystathionine beta-synthase.	0.658