STRINGSTRING
N300_01928 N300_01928 N300_13174 N300_13174 N300_10353 N300_10353 N300_10982 N300_10982 N300_03595 N300_03595 N300_07449 N300_07449 N300_03764 N300_03764 N300_04548 N300_04548 N300_01681 N300_01681 N300_07515 N300_07515 N300_10843 N300_10843 N300_03110 N300_03110 N300_05213 N300_05213 N300_12023 N300_12023 N300_14325 N300_14325 N300_06908 N300_06908 N300_14705 N300_14705 N300_12634 N300_12634 N300_07424 N300_07424 N300_10844 N300_10844
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
N300_01928Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2666 aa)
N300_13174X-ray repair cross-complementing protein 5. (612 aa)
N300_10353Serine/threonine-protein kinase Chk2. (516 aa)
N300_10982Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (432 aa)
N300_03595X-ray repair cross-complementing protein 5. (719 aa)
N300_07449DNA repair protein XRCC2. (266 aa)
N300_03764Bcl-2 homologous antagonist/killer. (187 aa)
N300_04548Mitogen-activated protein kinase kinase kinase MLT. (791 aa)
N300_01681Yorkie. (335 aa)
N300_07515DNA excision repair protein ERCC-6. (1495 aa)
N300_10843CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (427 aa)
N300_03110DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (296 aa)
N300_05213Breast cancer type 2 susceptibility protein. (3349 aa)
N300_12023C->U-editing enzyme APOBEC-1. (142 aa)
N300_14325Alpha-crystallin B chain; Belongs to the small heat shock protein (HSP20) family. (170 aa)
N300_06908DCN1-like protein. (304 aa)
N300_14705Receptor-type tyrosine-protein phosphatase C. (1109 aa)
N300_12634Apoptosis regulator Bcl-2. (239 aa)
N300_07424Non-specific serine/threonine protein kinase. (517 aa)
N300_10844Lysine-specific histone demethylase 1A. (681 aa)
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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