(30 nodes) Regulation of fatty acid metabolic process network (Calypte anna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	N300_05184	Progesterone-induced-blocking factor 1. (740 aa)
	N300_02636	Peroxisome proliferator-activated receptor alpha. (470 aa)
	N300_02969	Myelin P2 protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
	N300_14627	Protein-serine/threonine kinase. (244 aa)
	N300_07548	Erlin-1. (335 aa)
	N300_08270	NAD-dependent protein deacetylase sirtuin-4. (291 aa)
	N300_07250	Carbohydrate-responsive element-binding protein. (729 aa)
	N300_10426	Adiponectin. (238 aa)
	N300_13687	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (116 aa)
	N300_05821	WD and tetratricopeptide repeats protein 1. (659 aa)
	N300_03869	Lon protease homolog; Belongs to the peptidase S16 family. (775 aa)
	N300_12867	Solute carrier family 45 member 3. (561 aa)
	N300_01377	Apolipoprotein A-I. (250 aa)
	N300_12577	Oxysterols receptor LXR-alpha. (409 aa)
	N300_10584	HLA class II histocompatibility antigen gamma chain. (222 aa)
	N300_07688	NAD-dependent protein deacetylase sirtuin-1. (602 aa)
	N300_09413	Major facilitator superfamily domain-containing protein 2A. (456 aa)
	N300_11431	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1. (370 aa)
	N300_13944	Methyltransferase-like 20. (271 aa)
	N300_05040	Transcription factor Sox-9. (417 aa)
	N300_00982	Protein-serine/threonine kinase. (372 aa)
	N300_00416	ATP-binding cassette sub-family D member 2. (705 aa)
	N300_11712	Erlin-2. (236 aa)
	N300_03428	MCD domain-containing protein. (95 aa)
	N300_06070	Protein-serine/threonine kinase. (406 aa)
	N300_03311	Eukaryotic translation initiation factor 6. (179 aa)
	N300_09204	Annexin. (352 aa)
	N300_04551	Protein-serine/threonine kinase. (372 aa)
	N300_08627	DCC-interacting protein 13-beta. (640 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (481 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_00982	N300_06070	A0A091HXT0	A0A091HSB1	Protein-serine/threonine kinase.	Protein-serine/threonine kinase.	0.493
N300_01377	N300_02636	A0A091IBA6	A0A091IMK7	Apolipoprotein A-I.	Peroxisome proliferator-activated receptor alpha.	0.439
N300_02636	N300_01377	A0A091IMK7	A0A091IBA6	Peroxisome proliferator-activated receptor alpha.	Apolipoprotein A-I.	0.439
N300_02636	N300_07688	A0A091IMK7	A0A091I932	Peroxisome proliferator-activated receptor alpha.	NAD-dependent protein deacetylase sirtuin-1.	0.910
N300_02636	N300_10426	A0A091IMK7	A0A091IFM5	Peroxisome proliferator-activated receptor alpha.	Adiponectin.	0.526
N300_02636	N300_12577	A0A091IMK7	A0A091IA22	Peroxisome proliferator-activated receptor alpha.	Oxysterols receptor LXR-alpha.	0.604
N300_02969	PPARG	A0A091ILT4	A0A091HGU1	Myelin P2 protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.512
N300_03311	N300_10584	A0A091HS81	A0A091I9I9	Eukaryotic translation initiation factor 6.	HLA class II histocompatibility antigen gamma chain.	0.413
N300_04551	N300_06070	A0A091HL97	A0A091HSB1	Protein-serine/threonine kinase.	Protein-serine/threonine kinase.	0.491
N300_06070	N300_00982	A0A091HSB1	A0A091HXT0	Protein-serine/threonine kinase.	Protein-serine/threonine kinase.	0.493
N300_06070	N300_04551	A0A091HSB1	A0A091HL97	Protein-serine/threonine kinase.	Protein-serine/threonine kinase.	0.491
N300_06070	N300_14627	A0A091HSB1	A0A091IIW2	Protein-serine/threonine kinase.	Protein-serine/threonine kinase.	0.499
N300_07548	N300_11712	A0A091II71	A0A091HV51	Erlin-1.	Erlin-2.	0.590
N300_07688	N300_02636	A0A091I932	A0A091IMK7	NAD-dependent protein deacetylase sirtuin-1.	Peroxisome proliferator-activated receptor alpha.	0.910
N300_07688	N300_08270	A0A091I932	A0A091IHU2	NAD-dependent protein deacetylase sirtuin-1.	NAD-dependent protein deacetylase sirtuin-4.	0.910
N300_07688	N300_10426	A0A091I932	A0A091IFM5	NAD-dependent protein deacetylase sirtuin-1.	Adiponectin.	0.481
N300_07688	N300_12577	A0A091I932	A0A091IA22	NAD-dependent protein deacetylase sirtuin-1.	Oxysterols receptor LXR-alpha.	0.542
N300_07688	PPARG	A0A091I932	A0A091HGU1	NAD-dependent protein deacetylase sirtuin-1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.943
N300_08270	N300_07688	A0A091IHU2	A0A091I932	NAD-dependent protein deacetylase sirtuin-4.	NAD-dependent protein deacetylase sirtuin-1.	0.910
N300_08627	N300_10426	A0A091HJS7	A0A091IFM5	DCC-interacting protein 13-beta.	Adiponectin.	0.564