(81 nodes) Lamellipodium network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_02265	Sorting nexin-2. (482 aa)
	N300_07026	Wiskott-Aldrich syndrome protein family member 1. (572 aa)
	N300_01954	CD44 antigen. (377 aa)
	N300_11523	SH3 domain-binding protein 1. (604 aa)
	N300_15346	Integrin beta-1-binding protein 1. (200 aa)
	N300_15387	Alsin. (1662 aa)
	N300_14800	Kit ligand. (280 aa)
	N300_01502	Catenin beta-1. (777 aa)
	N300_09444	Wiskott-Aldrich syndrome protein family member 3. (502 aa)
	N300_03505	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (402 aa)
	N300_11239	Myosin light chain kinase, smooth muscle. (139 aa)
	N300_15014	E3 ubiquitin-protein ligase SH3RF1. (873 aa)
	N300_05066	Brain-specific angiogenesis inhibitor 1-associated protein 2. (497 aa)
	N300_05113	Ras-related C3 botulinum toxin substrate 3. (180 aa)
	N300_10516	Protein FAM206A. (130 aa)
	N300_06753	Rho guanine nucleotide exchange factor 7. (788 aa)
	N300_03517	Coronin; Belongs to the WD repeat coronin family. (413 aa)
	N300_07293	Intersectin-1. (1679 aa)
	N300_13948	FYVE, RhoGEF and PH domain-containing protein 4. (756 aa)
	N300_03577	Villin-1. (826 aa)
	N300_10515	Zinc transporter ZIP6. (185 aa)
	N300_03987	Sorting nexin-1. (391 aa)
	N300_12942	Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1323 aa)
	N300_10315	Coronin; Belongs to the WD repeat coronin family. (475 aa)
	N300_11515	Ras-related C3 botulinum toxin substrate 2. (195 aa)
	N300_12916	Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (888 aa)
	N300_14856	Calcineurin B homologous protein 3. (168 aa)
	N300_13048	Actin-binding LIM protein 3. (586 aa)
	N300_09950	Dystroglycan. (897 aa)
	N300_05174	Netrin receptor UNC5C. (867 aa)
	N300_08068	Unconventional myosin-Ib; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1100 aa)
	N300_13450	Protein enabled. (509 aa)
	N300_08878	MTSS1-like. (470 aa)
	N300_15840	Serine/threonine-protein kinase MRCK beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1522 aa)
	N300_11845	Clarin-1. (232 aa)
	N300_04603	Actin-binding LIM protein 1. (654 aa)
	N300_14352	Merlin. (443 aa)
	N300_07488	Phosphoinositide phospholipase C. (613 aa)
	N300_05816	Wiskott-Aldrich syndrome protein family member 2. (419 aa)
	N300_14738	Rab-3A-interacting protein. (466 aa)
	N300_15813	Actin, gamma-enteric smooth muscle. (376 aa)
	N300_12064	Villin-1. (695 aa)
	N300_01748	Tyrosine-protein phosphatase non-receptor type 13. (253 aa)
	N300_01234	Spermatogenesis-associated protein 13. (607 aa)
	N300_07757	Calcium and integrin-binding family member 3. (187 aa)
	N300_15184	Glycerophosphoinositol inositolphosphodiesterase GDPD2. (541 aa)
	N300_07076	Clarin-3. (225 aa)
	N300_01233	Uncharacterized protein. (567 aa)
	N300_13883	Coronin; Belongs to the WD repeat coronin family. (336 aa)
	N300_08377	Nuclear receptor-binding protein. (530 aa)
	N300_06010	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (272 aa)
	N300_13628	Integrin beta. (758 aa)
	N300_00979	Neurabin-1. (1006 aa)
	N300_11021	PDZ and LIM domain protein 4. (296 aa)
	N300_11401	Pleckstrin homology domain-containing family H member 2. (1499 aa)
	N300_03632	Myosin light chain kinase, smooth muscle. (1896 aa)
	N300_02111	Protein RUFY3. (457 aa)
	N300_03211	Cytoplasmic FMR1-interacting protein 1. (1254 aa)
	N300_02429	Src substrate protein p85. (516 aa)
	N300_03085	Polycystin-2. (563 aa)
	N300_07507	Actin, aortic smooth muscle. (377 aa)
	N300_07527	Tyrosine-protein phosphatase non-receptor type 20. (301 aa)
	N300_06887	Ras-related C3 botulinum toxin substrate 1. (180 aa)
	N300_08310	Adenomatous polyposis coli protein. (2835 aa)
	N300_04878	Nucleoside diphosphate kinase. (148 aa)
	N300_06453	Abl interactor 1. (448 aa)
	N300_04745	Rho guanine nucleotide exchange factor 6. (766 aa)
	N300_02959	Stathmin; Belongs to the stathmin family. (173 aa)
	N300_00524	Podocalyxin. (123 aa)
	N300_04164	Protocadherin Fat 1. (4517 aa)
	N300_02997	Calcium and integrin-binding protein 1. (152 aa)
	N300_14584	Merlin. (552 aa)
	N300_02935	Drebrin-like. (330 aa)
	N300_10476	CTTNBP2 N-terminal-like. (625 aa)
	N300_04169	Sorbin and SH3 domain-containing protein 2. (1171 aa)
	N300_04592	Shootin-1. (606 aa)
	N300_13478	Integrin-linked protein kinase. (320 aa)
	N300_06205	Integrin beta. (739 aa)
	N300_04550	Neurabin-1. (1052 aa)
	N300_06564	Alpha-parvin. (329 aa)
	N300_06546	Switch-associated protein 70. (553 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_00979	N300_04592	A0A091IN63	A0A091HSA4	Neurabin-1.	Shootin-1.	0.412
N300_01233	N300_01234	A0A091IIV8	A0A091IFS9	Uncharacterized protein.	Spermatogenesis-associated protein 13.	0.900
N300_01233	N300_01954	A0A091IIV8	A0A091HM00	Uncharacterized protein.	CD44 antigen.	0.541
N300_01233	N300_05113	A0A091IIV8	A0A091I254	Uncharacterized protein.	Ras-related C3 botulinum toxin substrate 3.	0.798
N300_01233	N300_06887	A0A091IIV8	A0A091J8B9	Uncharacterized protein.	Ras-related C3 botulinum toxin substrate 1.	0.798
N300_01233	N300_07293	A0A091IIV8	A0A091I4B2	Uncharacterized protein.	Intersectin-1.	0.605
N300_01233	N300_08310	A0A091IIV8	A0A091J9Y2	Uncharacterized protein.	Adenomatous polyposis coli protein.	0.891
N300_01233	N300_11515	A0A091IIV8	A0A091I877	Uncharacterized protein.	Ras-related C3 botulinum toxin substrate 2.	0.872
N300_01234	N300_01233	A0A091IFS9	A0A091IIV8	Spermatogenesis-associated protein 13.	Uncharacterized protein.	0.900
N300_01234	N300_01954	A0A091IFS9	A0A091HM00	Spermatogenesis-associated protein 13.	CD44 antigen.	0.541
N300_01234	N300_05113	A0A091IFS9	A0A091I254	Spermatogenesis-associated protein 13.	Ras-related C3 botulinum toxin substrate 3.	0.798
N300_01234	N300_06887	A0A091IFS9	A0A091J8B9	Spermatogenesis-associated protein 13.	Ras-related C3 botulinum toxin substrate 1.	0.798
N300_01234	N300_07293	A0A091IFS9	A0A091I4B2	Spermatogenesis-associated protein 13.	Intersectin-1.	0.605
N300_01234	N300_08310	A0A091IFS9	A0A091J9Y2	Spermatogenesis-associated protein 13.	Adenomatous polyposis coli protein.	0.891
N300_01234	N300_11515	A0A091IFS9	A0A091I877	Spermatogenesis-associated protein 13.	Ras-related C3 botulinum toxin substrate 2.	0.872
N300_01502	N300_01954	A0A091HZ16	A0A091HM00	Catenin beta-1.	CD44 antigen.	0.515
N300_01502	N300_03505	A0A091HZ16	A0A091I026	Catenin beta-1.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.495
N300_01502	N300_04164	A0A091HZ16	A0A091HW82	Catenin beta-1.	Protocadherin Fat 1.	0.530
N300_01502	N300_04878	A0A091HZ16	A0A091HYJ8	Catenin beta-1.	Nucleoside diphosphate kinase.	0.510
N300_01502	N300_05113	A0A091HZ16	A0A091I254	Catenin beta-1.	Ras-related C3 botulinum toxin substrate 3.	0.576