(33 nodes) Regulation of bone mineralization network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_12163	C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	N300_02132	BMP-2-inducible protein kinase. (598 aa)
	N300_07703	Serglycin. (83 aa)
	N300_03952	BCL-6 corepressor. (1755 aa)
	N300_02595	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (238 aa)
	N300_05640	Transforming growth factor beta-3. (295 aa)
	N300_15306	Protein odd-skipped-related 1. (249 aa)
	N300_11186	Progressive ankylosis protein. (463 aa)
	N300_06568	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (117 aa)
	N300_10233	Protein FAM101A. (216 aa)
	N300_11551	Extracellular serine/threonine protein kinase FAM20C. (404 aa)
	N300_04570	Pyridoxal phosphate phosphatase PHOSPHO2. (241 aa)
	N300_05716	Gamma-taxilin. (318 aa)
	N300_00845	Protein CYR61. (323 aa)
	N300_13712	G-protein coupled receptor 98; Belongs to the G-protein coupled receptor 2 family. (6204 aa)
	N300_11170	Protein FAM101B. (142 aa)
	N300_12588	Bone morphogenetic protein 6. (296 aa)
	N300_13398	Uncharacterized protein. (344 aa)
	N300_05040	Transcription factor Sox-9. (417 aa)
	N300_02697	Discoidin domain-containing receptor 2. (715 aa)
	N300_05110	Protein notum. (371 aa)
	N300_06684	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1031 aa)
	N300_11465	Protein kinase domain-containing protein, cytoplasmic. (246 aa)
	N300_11412	Protein kinase domain-containing protein, cytoplasmic. (279 aa)
	N300_02133	BMP-2-inducible protein kinase. (410 aa)
	N300_12402	Phosphoethanolamine/phosphocholine phosphatase. (240 aa)
	N300_09858	Extracellular serine/threonine protein kinase FAM20C. (401 aa)
	N300_08363	All-trans retinoic acid-induced differentiation factor. (148 aa)
	N300_11999	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (495 aa)
	N300_05175	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (457 aa)
	N300_07990	Discoidin domain-containing receptor 2. (742 aa)
	N300_02360	Neuronal membrane glycoprotein M6-b. (308 aa)
	N300_09538	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (470 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_02132	N300_02133	A0A091IVN1	A0A091I640	BMP-2-inducible protein kinase.	BMP-2-inducible protein kinase.	0.900
N300_02133	N300_02132	A0A091I640	A0A091IVN1	BMP-2-inducible protein kinase.	BMP-2-inducible protein kinase.	0.900
N300_02595	N300_06568	A0A091JAH0	A0A091HKJ2	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.530
N300_02595	N300_11551	A0A091JAH0	A0A091HLA3	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	Extracellular serine/threonine protein kinase FAM20C.	0.638
N300_05175	N300_05640	A0A091ID58	A0A091IBJ2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Transforming growth factor beta-3.	0.748
N300_05175	N300_06684	A0A091ID58	A0A091I2S0	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.937
N300_05175	N300_09538	A0A091ID58	A0A091IS52	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.838
N300_05175	N300_11999	A0A091ID58	A0A091IGW6	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.931
N300_05175	N300_12588	A0A091ID58	A0A091HVH4	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Bone morphogenetic protein 6.	0.929
N300_05640	N300_05175	A0A091IBJ2	A0A091ID58	Transforming growth factor beta-3.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.748
N300_05640	N300_06684	A0A091IBJ2	A0A091I2S0	Transforming growth factor beta-3.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.557
N300_05640	N300_09538	A0A091IBJ2	A0A091IS52	Transforming growth factor beta-3.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.759
N300_05640	N300_11999	A0A091IBJ2	A0A091IGW6	Transforming growth factor beta-3.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.896
N300_06568	N300_02595	A0A091HKJ2	A0A091JAH0	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.530
N300_06684	N300_05175	A0A091I2S0	A0A091ID58	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.937
N300_06684	N300_05640	A0A091I2S0	A0A091IBJ2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Transforming growth factor beta-3.	0.557
N300_06684	N300_09538	A0A091I2S0	A0A091IS52	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.947
N300_06684	N300_11999	A0A091I2S0	A0A091IGW6	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.966
N300_06684	N300_12588	A0A091I2S0	A0A091HVH4	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 6.	0.937
N300_09538	N300_05175	A0A091IS52	A0A091ID58	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.838