(43 nodes) Phosphatidylinositol-mediated signaling network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_15200	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1023 aa)
	N300_10591	Macrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (951 aa)
	N300_10671	Phosphoinositide phospholipase C. (811 aa)
	N300_00510	GATA-binding factor 3. (444 aa)
	N300_04134	Exocyst complex component 1. (895 aa)
	N300_08409	Carbonic anhydrase-related protein. (257 aa)
	N300_10147	Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2. (655 aa)
	N300_10809	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1069 aa)
	N300_11912	5-hydroxytryptamine receptor 2A. (471 aa)
	N300_00431	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1106 aa)
	N300_02342	G-protein coupled receptor 143. (393 aa)
	N300_13358	5-hydroxytryptamine receptor 2B. (429 aa)
	N300_07443	Phosphatidylinositide phosphatase SAC2. (1100 aa)
	N300_06722	Phosphoinositide phospholipase C. (1017 aa)
	N300_01540	Endothelin-1. (162 aa)
	N300_10851	Platelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (336 aa)
	N300_09625	Ezrin. (582 aa)
	N300_14475	Atrial natriuretic peptide receptor 3. (285 aa)
	N300_14554	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family. (859 aa)
	N300_00589	Alpha-1-antiproteinase F; Belongs to the serpin family. (357 aa)
	N300_10590	Platelet-derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1040 aa)
	N300_10897	Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (747 aa)
	N300_06518	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family. (1693 aa)
	N300_12813	Phosphoinositide-interacting protein. (132 aa)
	N300_03726	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta. (48 aa)
	N300_06361	Phosphoinositide phospholipase C. (1064 aa)
	N300_14682	Phosphoinositide phospholipase C. (575 aa)
	N300_07933	Proline-rich protein 5. (404 aa)
	N300_07218	Uncharacterized protein. (202 aa)
	N300_07488	Phosphoinositide phospholipase C. (613 aa)
	N300_04253	Neurofibromin. (76 aa)
	N300_04275	Membrane-associated phosphatidylinositol transfer protein 3. (964 aa)
	N300_07559	annotation not available (376 aa)
	N300_08170	Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2042 aa)
	N300_10532	Phosphoinositide phospholipase C. (1123 aa)
	N300_05885	Phosphoinositide phospholipase C. (1432 aa)
	N300_12063	Phosphoinositide phospholipase C. (589 aa)
	N300_04796	Kelch repeat and BTB domain-containing protein 2. (469 aa)
	N300_05980	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1050 aa)
	N300_03727	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1334 aa)
	N300_04254	Neurofibromin. (68 aa)
	N300_14681	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (1172 aa)
	N300_06401	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2. (462 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_00431	N300_03726	A0A091HYL1	A0A091ICT0	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta.	0.708
N300_00431	N300_03727	A0A091HYL1	A0A091J023	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family.	0.507
N300_00431	N300_05885	A0A091HYL1	A0A091II84	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.848
N300_00431	N300_05980	A0A091HYL1	A0A091ILR7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	0.923
N300_00431	N300_06361	A0A091HYL1	A0A091ICU2	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.845
N300_00431	N300_06401	A0A091HYL1	A0A091J562	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2.	0.865
N300_00431	N300_06518	A0A091HYL1	A0A091IAI3	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family.	0.507
N300_00431	N300_06722	A0A091HYL1	A0A091I2U3	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.647
N300_00431	N300_07443	A0A091HYL1	A0A091I0L9	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositide phosphatase SAC2.	0.597
N300_00431	N300_07488	A0A091HYL1	A0A091IEW5	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.828
N300_00431	N300_07559	A0A091HYL1	A0A091IG12	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	annotation not available	0.904
N300_00431	N300_08170	A0A091HYL1	A0A091IGL0	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.	0.576
N300_00431	N300_10532	A0A091HYL1	A0A091IGQ2	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.647
N300_00431	N300_10590	A0A091HYL1	A0A091I9J0	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Platelet-derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.769
N300_00431	N300_10591	A0A091HYL1	A0A091HKN6	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Macrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.686
N300_00431	N300_10671	A0A091HYL1	A0A091HRG5	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.845
N300_00431	N300_10809	A0A091HYL1	A0A091HXK2	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.	0.925
N300_00431	N300_14554	A0A091HYL1	A0A091I7U4	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	0.636
N300_00431	N300_14681	A0A091HYL1	A0A091J405	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family.	0.507
N300_00431	N300_14682	A0A091HYL1	A0A091IE41	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.	Phosphoinositide phospholipase C.	0.838