(14 nodes) Animal organ formation network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_04624	RNA-binding protein 20. (789 aa)
	N300_03761	LEM domain-containing protein 2. (393 aa)
	N300_09067	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (320 aa)
	N300_04865	Noggin. (216 aa)
	N300_07601	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (491 aa)
	N300_08902	Epithelial membrane protein 2. (167 aa)
	N300_09892	Androgen receptor. (381 aa)
	N300_13337	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (660 aa)
	N300_03644	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (524 aa)
	N300_10098	T-box brain protein 1. (662 aa)
	N300_09488	Homeobox protein Nkx-3.1. (59 aa)
	N300_01070	Homeobox protein Hox-A3. (413 aa)
	N300_04623	RNA-binding protein 20. (151 aa)
	N300_01502	Catenin beta-1. (777 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_01502	N300_03644	A0A091HZ16	A0A091I7H8	Catenin beta-1.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.501
N300_01502	N300_07601	A0A091HZ16	A0A091IK18	Catenin beta-1.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.562
N300_01502	N300_09067	A0A091HZ16	A0A091IQK7	Catenin beta-1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.631
N300_01502	N300_09892	A0A091HZ16	A0A091IE67	Catenin beta-1.	Androgen receptor.	0.906
N300_01502	N300_10098	A0A091HZ16	A0A091HJB6	Catenin beta-1.	T-box brain protein 1.	0.479
N300_03644	N300_01502	A0A091I7H8	A0A091HZ16	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Catenin beta-1.	0.501
N300_03644	N300_07601	A0A091I7H8	A0A091IK18	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.829
N300_04623	N300_04624	A0A091HSH0	A0A091HP67	RNA-binding protein 20.	RNA-binding protein 20.	0.918
N300_04624	N300_04623	A0A091HP67	A0A091HSH0	RNA-binding protein 20.	RNA-binding protein 20.	0.918
N300_07601	N300_01502	A0A091IK18	A0A091HZ16	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Catenin beta-1.	0.562
N300_07601	N300_03644	A0A091IK18	A0A091I7H8	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.829
N300_09067	N300_01502	A0A091IQK7	A0A091HZ16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Catenin beta-1.	0.631
N300_09892	N300_01502	A0A091IE67	A0A091HZ16	Androgen receptor.	Catenin beta-1.	0.906
N300_10098	N300_01502	A0A091HJB6	A0A091HZ16	T-box brain protein 1.	Catenin beta-1.	0.479