(12 nodes) Response to growth hormone network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_00701	Signal transducer and transcription activator 6. (411 aa)
	N300_13514	Growth hormone receptor. (588 aa)
	N300_07948	Somatotropin. (93 aa)
	N300_06652	Suppressor of cytokine signaling 2. (149 aa)
	N300_12437	Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (617 aa)
	N300_06163	Signal transducer and activator of transcription 5B. (354 aa)
	N300_00642	Tyrosine-protein kinase. (1160 aa)
	N300_11456	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	N300_15541	Tyrosine-protein kinase. (1131 aa)
	N300_03587	Insulin-like growth factor-binding protein 5. (159 aa)
	N300_05740	Metalloendopeptidase PEX. (712 aa)
	N300_06164	Signal transducer and activator of transcription. (770 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_00642	N300_00701	A0A091I984	A0A091IYT3	Tyrosine-protein kinase.	Signal transducer and transcription activator 6.	0.924
N300_00642	N300_06163	A0A091I984	A0A091ICQ4	Tyrosine-protein kinase.	Signal transducer and activator of transcription 5B.	0.924
N300_00642	N300_06164	A0A091I984	A0A091HNR2	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.964
N300_00642	N300_06652	A0A091I984	A0A091IGD8	Tyrosine-protein kinase.	Suppressor of cytokine signaling 2.	0.889
N300_00642	N300_07948	A0A091I984	A0A091IJE0	Tyrosine-protein kinase.	Somatotropin.	0.827
N300_00642	N300_13514	A0A091I984	A0A091IK88	Tyrosine-protein kinase.	Growth hormone receptor.	0.924
N300_00642	N300_15541	A0A091I984	A0A091I5H9	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.907
N300_00701	N300_00642	A0A091IYT3	A0A091I984	Signal transducer and transcription activator 6.	Tyrosine-protein kinase.	0.924
N300_00701	N300_06164	A0A091IYT3	A0A091HNR2	Signal transducer and transcription activator 6.	Signal transducer and activator of transcription.	0.851
N300_00701	N300_06652	A0A091IYT3	A0A091IGD8	Signal transducer and transcription activator 6.	Suppressor of cytokine signaling 2.	0.836
N300_00701	N300_07948	A0A091IYT3	A0A091IJE0	Signal transducer and transcription activator 6.	Somatotropin.	0.465
N300_00701	N300_13514	A0A091IYT3	A0A091IK88	Signal transducer and transcription activator 6.	Growth hormone receptor.	0.653
N300_00701	N300_15541	A0A091IYT3	A0A091I5H9	Signal transducer and transcription activator 6.	Tyrosine-protein kinase.	0.929
N300_06163	N300_00642	A0A091ICQ4	A0A091I984	Signal transducer and activator of transcription 5B.	Tyrosine-protein kinase.	0.924
N300_06163	N300_06164	A0A091ICQ4	A0A091HNR2	Signal transducer and activator of transcription 5B.	Signal transducer and activator of transcription.	0.843
N300_06163	N300_06652	A0A091ICQ4	A0A091IGD8	Signal transducer and activator of transcription 5B.	Suppressor of cytokine signaling 2.	0.836
N300_06163	N300_07948	A0A091ICQ4	A0A091IJE0	Signal transducer and activator of transcription 5B.	Somatotropin.	0.465
N300_06163	N300_13514	A0A091ICQ4	A0A091IK88	Signal transducer and activator of transcription 5B.	Growth hormone receptor.	0.653
N300_06163	N300_15541	A0A091ICQ4	A0A091I5H9	Signal transducer and activator of transcription 5B.	Tyrosine-protein kinase.	0.929
N300_06164	N300_00642	A0A091HNR2	A0A091I984	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.964