(62 nodes) Skeletal muscle organ development network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_10078	Desmin; Belongs to the intermediate filament family. (449 aa)
	N300_08606	Glycosyltransferase-like LARGE1. (756 aa)
	N300_00582	Ankyrin repeat and SOCS box protein 2. (647 aa)
	N300_04531	Homeobox protein Hox-D10. (296 aa)
	N300_03445	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (421 aa)
	N300_05241	Protein FAM65B. (1089 aa)
	N300_06510	Myogenic factor. (298 aa)
	N300_04591	Ventral anterior homeobox 1. (183 aa)
	N300_12465	Neuralized-like 1A. (546 aa)
	N300_13825	COP9 signalosome complex subunit 2. (436 aa)
	N300_09514	Ankyrin repeat domain-containing protein 33. (349 aa)
	N300_12634	Apoptosis regulator Bcl-2. (239 aa)
	N300_11729	Bridging integrator 3. (100 aa)
	N300_02813	Ankyrin repeat domain-containing protein 33B. (373 aa)
	N300_09503	Nuclear receptor subfamily 4 group A member 1. (116 aa)
	N300_11918	Retinoblastoma-associated protein. (871 aa)
	N300_09727	Transcription factor 21. (170 aa)
	N300_04871	Hepatic leukemia factor. (248 aa)
	N300_01016	Homeobox protein MOX-2. (298 aa)
	N300_03008	Cyclin-T2; Belongs to the cyclin family. (695 aa)
	N300_03012	R3H domain-containing protein 1. (1086 aa)
	N300_11437	Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
	N300_10982	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (432 aa)
	N300_09624	Protein dispatched 1. (1540 aa)
	N300_13543	Growth/differentiation factor 8. (375 aa)
	N300_08822	General transcription factor 3C polypeptide 5. (495 aa)
	N300_11456	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	N300_09871	Stimulated by retinoic acid 6. (621 aa)
	N300_09593	Transcription cofactor vestigial-like 2. (306 aa)
	N300_07172	Homeobox protein BarH-like 2. (262 aa)
	N300_07639	Multiple epidermal growth factor-like domains protein 10. (1130 aa)
	N300_11800	Myozenin-1. (308 aa)
	N300_09950	Dystroglycan. (897 aa)
	N300_14776	B-cell CLL/lymphoma 9 protein. (1417 aa)
	N300_06993	Blood vessel epicardial substance. (575 aa)
	N300_11321	Krueppel-like factor 5. (376 aa)
	N300_13584	Popeye domain-containing protein 2. (354 aa)
	N300_00698	R3H domain-containing protein 2. (767 aa)
	N300_13688	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (113 aa)
	N300_03697	Myogenin. (187 aa)
	N300_05855	Selenoprotein N. (503 aa)
	N300_13687	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (116 aa)
	N300_02916	Growth/differentiation factor 11. (231 aa)
	N300_04253	Neurofibromin. (76 aa)
	N300_07496	Ankyrin repeat domain-containing protein 1. (307 aa)
	N300_05185	Krueppel-like factor 5. (373 aa)
	N300_01848	Histone-lysine N-methyltransferase SMYD1. (491 aa)
	N300_07233	Elastin. (219 aa)
	N300_04087	Paired mesoderm homeobox protein 2B. (141 aa)
	N300_01768	Myozenin-2. (238 aa)
	N300_07596	Eomesodermin. (391 aa)
	N300_14606	Homeobox protein Hox-C10. (300 aa)
	N300_02824	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (611 aa)
	N300_04321	Homer protein 1. (354 aa)
	N300_14650	Myocyte-specific enhancer factor 2D. (313 aa)
	N300_09617	H2.0-like homeobox protein. (137 aa)
	N300_03738	Protein BTG2. (134 aa)
	N300_03761	LEM domain-containing protein 2. (393 aa)
	N300_05153	Pituitary homeobox 2. (257 aa)
	N300_04254	Neurofibromin. (68 aa)
	N300_06864	Inactive serine/threonine-protein kinase VRK3. (269 aa)
	N300_13635	Supervillin. (2187 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_00582	N300_07496	A0A091HKI6	A0A091IFV9	Ankyrin repeat and SOCS box protein 2.	Ankyrin repeat domain-containing protein 1.	0.515
N300_00582	N300_09514	A0A091HKI6	A0A091HTP3	Ankyrin repeat and SOCS box protein 2.	Ankyrin repeat domain-containing protein 33.	0.441
N300_02813	N300_02824	A0A091HV42	A0A091IL56	Ankyrin repeat domain-containing protein 33B.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.406
N300_02824	N300_02813	A0A091IL56	A0A091HV42	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Ankyrin repeat domain-containing protein 33B.	0.406
N300_02824	N300_08822	A0A091IL56	A0A091I5S3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	General transcription factor 3C polypeptide 5.	0.424
N300_02824	N300_09514	A0A091IL56	A0A091HTP3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Ankyrin repeat domain-containing protein 33.	0.406
N300_02824	N300_11456	A0A091IL56	A0A091I6I9	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.450
N300_02824	N300_12465	A0A091IL56	A0A091HPQ7	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neuralized-like 1A.	0.425
N300_03445	N300_09624	A0A091HMS2	A0A091I4T5	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein dispatched 1.	0.497
N300_03697	N300_06510	A0A091ICD3	A0A091HNJ1	Myogenin.	Myogenic factor.	0.712
N300_03697	N300_14650	A0A091ICD3	A0A091INN8	Myogenin.	Myocyte-specific enhancer factor 2D.	0.804
N300_03738	N300_09503	A0A091J034	A0A091HWW5	Protein BTG2.	Nuclear receptor subfamily 4 group A member 1.	0.449
N300_03761	N300_08822	A0A091J055	A0A091I5S3	LEM domain-containing protein 2.	General transcription factor 3C polypeptide 5.	0.424
N300_03761	N300_12465	A0A091J055	A0A091HPQ7	LEM domain-containing protein 2.	Neuralized-like 1A.	0.413
N300_04253	N300_04254	A0A091IFF6	A0A091J2P9	Neurofibromin.	Neurofibromin.	0.929
N300_04254	N300_04253	A0A091J2P9	A0A091IFF6	Neurofibromin.	Neurofibromin.	0.929
N300_04871	N300_11437	A0A091HZH5	A0A091I364	Hepatic leukemia factor.	Cyclic AMP-dependent transcription factor ATF-3.	0.426
N300_04871	N300_12634	A0A091HZH5	A0A091HUI8	Hepatic leukemia factor.	Apoptosis regulator Bcl-2.	0.447
N300_05185	N300_08822	A0A091IH68	A0A091I5S3	Krueppel-like factor 5.	General transcription factor 3C polypeptide 5.	0.480
N300_06510	N300_03697	A0A091HNJ1	A0A091ICD3	Myogenic factor.	Myogenin.	0.712