(36 nodes) Precatalytic spliceosome network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_13180	PHD finger-like domain-containing protein 5A. (93 aa)
	N300_02988	Microfibrillar-associated protein 1. (421 aa)
	N300_10917	Splicing factor 3B subunit 4. (244 aa)
	N300_03734	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (76 aa)
	N300_15126	Zinc finger matrin-type protein 2. (193 aa)
	N300_03056	U6 snRNA-associated Sm-like LSm6. (80 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (121 aa)
	N300_15273	Thioredoxin-like 4A. (129 aa)
	N300_05877	Splicing factor 3A subunit 3. (457 aa)
	N300_14716	Pre-mRNA-splicing factor 38B. (426 aa)
	N300_02315	WW domain-binding protein 4. (396 aa)
	N300_10538	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	N300_01514	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (117 aa)
	N300_03468	Pre-mRNA-processing-splicing factor 8. (2318 aa)
	N300_15673	Pre-mRNA-processing factor 6. (924 aa)
	N300_11297	RNA-binding motif protein, X-linked 2. (118 aa)
	N300_08229	Small nuclear ribonucleoprotein Sm D3. (126 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (67 aa)
	N300_13173	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (127 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	N300_09472	Small nuclear ribonucleoprotein G. (76 aa)
	N300_04010	Pre-mRNA-splicing factor 38A. (312 aa)
	N300_04496	Pre-mRNA-splicing factor CWC22. (870 aa)
	N300_06220	RING finger protein 113A. (307 aa)
	N300_10380	Pre-mRNA branch site protein p14. (115 aa)
	N300_06667	Small nuclear ribonucleoprotein F. (65 aa)
	N300_15492	Smad nuclear-interacting protein 1. (237 aa)
	N300_08080	U2 small nuclear ribonucleoprotein A. (228 aa)
	N300_08742	U6 snRNA-associated Sm-like LSm7. (101 aa)
	N300_10497	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16. (153 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (88 aa)
	N300_11247	116 kDa U5 small nuclear ribonucleoprotein component. (972 aa)
	N300_12736	WD40 repeat-containing protein SMU1. (505 aa)
	N300_05459	U5 small nuclear ribonucleoprotein 200 kDa helicase. (185 aa)
	N300_15596	Small nuclear ribonucleoprotein-associated protein B. (188 aa)
	N300_11669	Splicing factor 3A subunit 2. (205 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM3	LSM4	A0A091HJE7	A0A091IG16	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.998
LSM3	LSM5	A0A091HJE7	A0A091J8X2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.999
LSM3	LSM8	A0A091HJE7	A0A091HYG9	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM3	N300_01514	A0A091HJE7	A0A091IL90	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.987
LSM3	N300_02315	A0A091HJE7	A0A091IJG1	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	WW domain-binding protein 4.	0.734
LSM3	N300_02988	A0A091HJE7	A0A091IA55	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Microfibrillar-associated protein 1.	0.741
LSM3	N300_03056	A0A091HJE7	A0A091IDD6	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like LSm6.	0.999
LSM3	N300_03468	A0A091HJE7	A0A091IQB6	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA-processing-splicing factor 8.	0.989
LSM3	N300_03734	A0A091HJE7	A0A091IAC4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.998
LSM3	N300_04010	A0A091HJE7	A0A091HKR1	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA-splicing factor 38A.	0.743
LSM3	N300_05459	A0A091HJE7	A0A091I3W2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U5 small nuclear ribonucleoprotein 200 kDa helicase.	0.989
LSM3	N300_05877	A0A091HJE7	A0A091IHP8	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Splicing factor 3A subunit 3.	0.925
LSM3	N300_06667	A0A091HJE7	A0A091HUI0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein F.	0.991
LSM3	N300_08080	A0A091HJE7	A0A091HVR0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U2 small nuclear ribonucleoprotein A.	0.945
LSM3	N300_08229	A0A091HJE7	A0A091J7S9	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3.	0.993
LSM3	N300_08742	A0A091HJE7	A0A091HWI9	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like LSm7.	0.998
LSM3	N300_09472	A0A091HJE7	A0A091HK12	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein G.	0.993
LSM3	N300_10380	A0A091HJE7	A0A091HTM7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA branch site protein p14.	0.808
LSM3	N300_10538	A0A091HJE7	A0A091IKU6	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Splicing factor 3B subunit 5; Belongs to the SF3B5 family.	0.923
LSM3	N300_10917	A0A091HJE7	A0A091IA91	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Splicing factor 3B subunit 4.	0.876