(32 nodes) Regulation of stem cell proliferation network (Calypte anna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	N300_12501	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
	N300_14584	Merlin. (552 aa)
	N300_04200	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (371 aa)
	N300_08716	NAD-dependent protein deacetylase sirtuin-6. (340 aa)
	N300_11147	T-box transcription factor TBX2-B. (617 aa)
	N300_06357	Fermitin family 1. (627 aa)
	N300_04253	Neurofibromin. (76 aa)
	N300_01583	Fermitin family 2. (629 aa)
	N300_04824	High mobility group protein B2. (208 aa)
	N300_05824	Uncharacterized protein C1orf172. (342 aa)
	N300_08194	Microprocessor complex subunit DGCR8. (775 aa)
	N300_07601	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (491 aa)
	N300_02570	High mobility group protein HMGI-C. (46 aa)
	N300_05210	NEDD4-binding protein 2-like 2. (644 aa)
	N300_09067	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (320 aa)
	N300_04254	Neurofibromin. (68 aa)
	N300_11493	Programmed cell death protein 2. (189 aa)
	N300_05211	Uncharacterized protein. (148 aa)
	N300_14705	Receptor-type tyrosine-protein phosphatase C. (1109 aa)
	N300_14352	Merlin. (443 aa)
	N300_05040	Transcription factor Sox-9. (417 aa)
	N300_01070	Homeobox protein Hox-A3. (413 aa)
	N300_13337	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (660 aa)
	N300_13902	Cyclin-dependent kinase 4 inhibitor C. (158 aa)
	N300_10844	Lysine-specific histone demethylase 1A. (681 aa)
	N300_11968	Paired mesoderm homeobox protein 1. (157 aa)
	N300_09577	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
	N300_03644	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (524 aa)
	N300_14851	Uncharacterized protein. (167 aa)
	N300_09110	Ataxin-1-like. (636 aa)
	N300_11201	Epithelial cell adhesion molecule. (273 aa)
	N300_04129	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (660 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_03644	N300_07601	A0A091I7H8	A0A091IK18	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.829
N300_04129	N300_04200	A0A091HSW4	A0A091HU49	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.962
N300_04129	N300_12501	A0A091HSW4	A0A091HT20	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.902
N300_04129	N300_14705	A0A091HSW4	A0A091J8Q8	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Receptor-type tyrosine-protein phosphatase C.	0.400
N300_04200	N300_04129	A0A091HU49	A0A091HSW4	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.962
N300_04253	N300_04254	A0A091IFF6	A0A091J2P9	Neurofibromin.	Neurofibromin.	0.929
N300_04254	N300_04253	A0A091J2P9	A0A091IFF6	Neurofibromin.	Neurofibromin.	0.929
N300_04824	N300_10844	A0A091IH21	A0A091I3T2	High mobility group protein B2.	Lysine-specific histone demethylase 1A.	0.675
N300_05210	N300_05211	A0A091IKZ1	A0A091J8G4	NEDD4-binding protein 2-like 2.	Uncharacterized protein.	0.899
N300_05211	N300_05210	A0A091J8G4	A0A091IKZ1	Uncharacterized protein.	NEDD4-binding protein 2-like 2.	0.899
N300_07601	N300_03644	A0A091IK18	A0A091I7H8	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.829
N300_08716	N300_13337	A0A091HWG2	A0A091HZ84	NAD-dependent protein deacetylase sirtuin-6.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.642
N300_10844	N300_04824	A0A091I3T2	A0A091IH21	Lysine-specific histone demethylase 1A.	High mobility group protein B2.	0.675
N300_11201	N300_14705	A0A091HN36	A0A091J8Q8	Epithelial cell adhesion molecule.	Receptor-type tyrosine-protein phosphatase C.	0.410
N300_12501	N300_04129	A0A091HT20	A0A091HSW4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.902
N300_13337	N300_08716	A0A091HZ84	A0A091HWG2	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	NAD-dependent protein deacetylase sirtuin-6.	0.642
N300_13337	N300_13902	A0A091HZ84	A0A091I0K4	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	Cyclin-dependent kinase 4 inhibitor C.	0.541
N300_13902	N300_13337	A0A091I0K4	A0A091HZ84	Cyclin-dependent kinase 4 inhibitor C.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.541
N300_14352	N300_14584	A0A091IET4	A0A091HTN3	Merlin.	Merlin.	0.827
N300_14584	N300_14352	A0A091HTN3	A0A091IET4	Merlin.	Merlin.	0.827