(64 nodes) KEAP1-NFE2L2 pathway network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_06264	Proteasome activator complex subunit 4. (1775 aa)
	N300_06258	Ubiquitin-40S ribosomal protein S27a. (160 aa)
	N300_12559	Proteasome subunit alpha type. (266 aa)
	N300_01064	Nuclear factor erythroid 2-related factor 3; Belongs to the bZIP family. (295 aa)
	N300_06972	RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (464 aa)
	N300_14818	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (706 aa)
	N300_13357	26S proteasome non-ATPase regulatory subunit 1. (951 aa)
	N300_14059	Spermatogenesis-associated protein 5. (772 aa)
	N300_01581	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
	N300_03683	Proteasome endopeptidase complex. (209 aa)
	N300_02882	26S protease regulatory subunit 8. (339 aa)
	N300_12570	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (414 aa)
	N300_15652	Proteasome inhibitor PI31 subunit. (229 aa)
	N300_11031	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	N300_11235	26S proteasome non-ATPase regulatory subunit 11. (74 aa)
	N300_04658	26S proteasome non-ATPase regulatory subunit 10. (189 aa)
	N300_08324	F-box/LRR-repeat protein 17. (328 aa)
	N300_05991	Kelch-like 17. (596 aa)
	N300_13386	Mitochondrial ubiquitin ligase activator of nfkb 1-A. (105 aa)
	N300_00444	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	N300_07632	Cullin-1; Belongs to the cullin family. (782 aa)
	N300_11495	Proteasome subunit beta type-1. (167 aa)
	N300_06809	CREB-binding protein. (1334 aa)
	N300_10748	26S protease regulatory subunit 10B. (116 aa)
	N300_08183	Ubiquitin fusion degradation protein 1. (306 aa)
	N300_15190	Sestrin-3. (425 aa)
	N300_01611	Proteasome subunit alpha type. (190 aa)
	N300_07791	KxDL motif-containing protein 1. (175 aa)
	N300_10273	26S proteasome non-ATPase regulatory subunit 9. (209 aa)
	N300_11560	Cyclic AMP-dependent transcription factor ATF-4. (355 aa)
	N300_10097	26S proteasome non-ATPase regulatory subunit 14. (310 aa)
	N300_10150	Cullin-3; Belongs to the cullin family. (746 aa)
	N300_15471	Proteasome subunit beta. (171 aa)
	N300_01468	Mitochondrial ubiquitin ligase activator of NFKB 1. (310 aa)
	N300_00762	Peroxiredoxin-1. (201 aa)
	N300_09354	Proteasome subunit beta. (259 aa)
	N300_12497	F-box/WD repeat-containing protein 1A. (593 aa)
	N300_06182	Proteasome activator complex subunit 3. (241 aa)
	N300_11597	RAC-alpha serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (468 aa)
	N300_05693	Proteasome endopeptidase complex. (222 aa)
	N300_11574	RING-box protein 1. (78 aa)
	N300_10898	26S proteasome non-ATPase regulatory subunit 4. (298 aa)
	N300_00555	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (439 aa)
	N300_10598	Sequestosome-1. (393 aa)
	N300_09118	26S proteasome non-ATPase regulatory subunit 7. (298 aa)
	N300_15894	UBX domain-containing protein 7. (467 aa)
	N300_00727	Proteasome endopeptidase complex. (227 aa)
	N300_06097	Proteasome subunit beta type-3. (175 aa)
	N300_13586	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (371 aa)
	N300_09840	Transcription factor MafK. (156 aa)
	N300_15503	RAC-beta serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (460 aa)
	N300_10892	Uncharacterized protein. (232 aa)
	N300_07015	Sestrin-1. (506 aa)
	N300_09174	Microtubule-associated proteins 1A/1B light chain 3B. (105 aa)
	N300_04492	26S proteasome non-ATPase regulatory subunit 6. (343 aa)
	N300_15711	Proteasome subunit alpha type. (248 aa)
	N300_08768	26S proteasome non-ATPase regulatory subunit 5. (447 aa)
	N300_07321	Transcription regulator protein BACH1. (766 aa)
	N300_01162	Transcription regulator protein BACH2. (824 aa)
	N300_03535	Polyubiquitin. (290 aa)
	N300_05055	Nuclear protein localization protein 4. (548 aa)
	N300_05012	26S proteasome non-ATPase regulatory subunit 12. (360 aa)
	N300_07396	S-phase kinase-associated protein 2. (403 aa)
	N300_13388	26S proteasome non-ATPase regulatory subunit 2. (858 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_00444	N300_00555	A0A091IKT9	A0A091HKP7	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S protease regulatory subunit 4; Belongs to the AAA ATPase family.	0.999
N300_00444	N300_00727	A0A091IKT9	A0A091ICM7	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Proteasome endopeptidase complex.	0.999
N300_00444	N300_01064	A0A091IKT9	A0A091HYY5	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Nuclear factor erythroid 2-related factor 3; Belongs to the bZIP family.	0.690
N300_00444	N300_01162	A0A091IKT9	A0A091I3P4	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Transcription regulator protein BACH2.	0.599
N300_00444	N300_01581	A0A091IKT9	A0A091J3R5	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.989
N300_00444	N300_01611	A0A091IKT9	A0A091IG53	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Proteasome subunit alpha type.	0.998
N300_00444	N300_02882	A0A091IKT9	A0A091IYW6	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S protease regulatory subunit 8.	0.999
N300_00444	N300_03535	A0A091IKT9	A0A091I394	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Polyubiquitin.	0.970
N300_00444	N300_03683	A0A091IKT9	A0A091IZY3	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Proteasome endopeptidase complex.	0.999
N300_00444	N300_04492	A0A091IKT9	A0A091I6N0	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 6.	0.999
N300_00444	N300_04658	A0A091IKT9	A0A091IM12	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 10.	0.991
N300_00444	N300_05012	A0A091IKT9	A0A091I1Y5	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 12.	0.999
N300_00444	N300_05693	A0A091IKT9	A0A091HLM6	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Proteasome endopeptidase complex.	0.997
N300_00444	N300_05991	A0A091IKT9	A0A091ILS4	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Kelch-like 17.	0.601
N300_00444	N300_06097	A0A091IKT9	A0A091ICK4	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Proteasome subunit beta type-3.	0.994
N300_00444	N300_06182	A0A091IKT9	A0A091HMP6	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Proteasome activator complex subunit 3.	0.742
N300_00444	N300_06258	A0A091IKT9	A0A091HZ70	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Ubiquitin-40S ribosomal protein S27a.	0.970
N300_00444	N300_06264	A0A091IKT9	A0A091HZ73	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Proteasome activator complex subunit 4.	0.819
N300_00444	N300_07321	A0A091IKT9	A0A091I4D1	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Transcription regulator protein BACH1.	0.599
N300_00444	N300_07396	A0A091IKT9	A0A091HZJ4	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	S-phase kinase-associated protein 2.	0.607