(131 nodes) Epidermal growth factor-like domain. network (Calypte anna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N300_03024	Von Willebrand factor D and EGF domain-containing protein. (519 aa)
	N300_01005	Von Willebrand factor D and EGF domain-containing protein. (155 aa)
	N300_11249	Disintegrin and metalloproteinase domain-containing protein 11. (540 aa)
	N300_14945	Low-density lipoprotein receptor-related protein 2. (665 aa)
	N300_14922	Multimerin-1. (1015 aa)
	N300_10717	Vitamin K-dependent protein S. (638 aa)
	N300_02653	BMP/retinoic acid-inducible neural-specific protein 2. (725 aa)
	N300_03023	Von Willebrand factor D and EGF domain-containing protein. (130 aa)
	N300_01002	Thrombospondin type-1 domain-containing protein 7A. (1587 aa)
	N300_01004	Von Willebrand factor D and EGF domain-containing protein. (135 aa)
	N300_02293	Pro-neuregulin-1, membrane-bound isoform. (576 aa)
	N300_04668	Teneurin-1. (2470 aa)
	N300_08712	Fibrillin-2. (2862 aa)
	N300_11096	Thrombospondin-2. (992 aa)
	N300_04192	Teneurin-3. (2545 aa)
	N300_00396	Cysteine-rich with EGF-like domain protein 2-A. (294 aa)
	N300_07414	Pikachurin. (987 aa)
	N300_04164	Protocadherin Fat 1. (4517 aa)
	N300_09357	Fibropellin-1. (566 aa)
	N300_05767	Integrin beta-like 1. (389 aa)
	N300_14889	Disintegrin and metalloproteinase domain-containing protein 19. (652 aa)
	N300_13723	EGF-like repeat and discoidin I-like domain-containing protein 3. (457 aa)
	N300_10364	Metalloendopeptidase. (628 aa)
	N300_14559	Scavenger receptor class F member 1. (763 aa)
	N300_12512	Slit 1 protein. (1151 aa)
	N300_08079	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (854 aa)
	N300_04600	Attractin-like 1. (1132 aa)
	N300_03353	Neural-cadherin; Cadherins are calcium-dependent cell adhesion proteins. (2360 aa)
	N300_12105	Multiple epidermal growth factor-like domains protein 11. (137 aa)
	N300_04611	Hyaluronan-binding protein 2. (481 aa)
	N300_07053	C-type lectin domain family 18 member A. (396 aa)
	N300_04605	Von Willebrand factor A domain-containing protein 2. (709 aa)
	N300_08065	Tomoregulin-2. (317 aa)
	N300_05659	Latent-transforming growth factor beta-binding protein 2. (1621 aa)
	N300_08665	Nephronectin. (589 aa)
	N300_07942	Fibulin-1. (674 aa)
	N300_07926	Signal peptide, CUB and EGF-like domain-containing protein 1. (992 aa)
	N300_06540	Signal peptide, CUB and EGF-like domain-containing protein 2. (975 aa)
	N300_06176	Contactin-associated protein 1. (785 aa)
	N300_10571	Protocadherin Fat 2. (4390 aa)
	N300_04577	Low-density lipoprotein receptor-related protein 2. (4627 aa)
	N300_06611	Protein kinase C-binding protein NELL1. (790 aa)
	N300_09681	Sortilin-related receptor. (2109 aa)
	N300_04023	Low-density lipoprotein receptor-related protein 8. (805 aa)
	N300_15302	Matrilin-3. (382 aa)
	N300_01308	Neural-cadherin; Cadherins are calcium-dependent cell adhesion proteins. (2530 aa)
	N300_07840	Protein eyes shut. (395 aa)
	N300_12235	Nidogen-2. (1100 aa)
	N300_08127	Proheparin-binding EGF-like growth factor. (135 aa)
	N300_15858	Protein delta 1. (354 aa)
	N300_07970	Tenascin-R. (1309 aa)
	N300_02127	Epigen. (151 aa)
	N300_08788	Epidermal growth factor-like 7. (231 aa)
	N300_09798	Nidogen-1. (1205 aa)
	N300_15087	Growth arrest-specific protein 6. (643 aa)
	N300_09094	Teneurin-4. (2482 aa)
	N300_02709	Neurogenic locus notch protein 2. (562 aa)
	N300_02355	Epidermal growth factor-like 6. (520 aa)
	N300_12553	Pro-neuregulin-4, membrane-bound isoform. (82 aa)
	N300_01006	Von Willebrand factor D and EGF domain-containing protein. (509 aa)
	N300_07633	Contactin-associated protein-like 2. (576 aa)
	N300_11810	Urokinase-type plasminogen activator. (386 aa)
	N300_04739	Coagulation factor IX. (440 aa)
	N300_02824	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (611 aa)
	N300_00373	Hyaluronidase. (431 aa)
	N300_08363	All-trans retinoic acid-induced differentiation factor. (148 aa)
	N300_02629	Low-density lipoprotein receptor-related protein 6. (1594 aa)
	N300_01323	Matrilin-2. (894 aa)
	N300_07839	Protein eyes shut. (414 aa)
	N300_02567	Wnt inhibitory factor 1. (319 aa)
	N300_15918	Slit 3 protein. (1118 aa)
	N300_14721	Netrin-G1. (514 aa)
	N300_14701	Protein crumbs 1. (1381 aa)
	N300_14684	Prostaglandin G/H synthase 2. (587 aa)
	N300_13829	Fibrillin-1. (2815 aa)
	N300_04356	Very low-density lipoprotein receptor. (827 aa)
	N300_09384	Netrin-G2. (483 aa)
	N300_03122	Disintegrin and metalloproteinase domain-containing protein 9. (830 aa)
	N300_06851	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (400 aa)
	N300_09304	Hemicentin-2. (383 aa)
	N300_11682	Scavenger receptor class F member 2. (608 aa)
	N300_13467	Neurexin-1. (1136 aa)
	N300_03049	Hedgehog-interacting protein. (609 aa)
	N300_00805	Tyrosine-protein kinase receptor Tie-1. (1055 aa)
	N300_01798	Hepatocyte growth factor activator. (560 aa)
	N300_01721	Protocadherin Fat 3. (3460 aa)
	N300_08846	Delta-like 4. (666 aa)
	N300_03271	Matrilin-4. (603 aa)
	N300_07785	Cartilage oligomeric matrix protein. (729 aa)
	N300_12106	Multiple epidermal growth factor-like domains protein 11. (914 aa)
	N300_01662	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1211 aa)
	N300_03747	Signal peptide, CUB and EGF-like domain-containing protein 3. (976 aa)
	N300_08952	Disintegrin and metalloproteinase domain-containing protein 19. (807 aa)
	N300_08130	Pro-neuregulin-2, membrane-bound isoform. (539 aa)
	N300_10057	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3610 aa)
	N300_06370	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1193 aa)
	N300_09978	Hyaluronidase. (401 aa)
	N300_14483	Collagen and calcium-binding EGF domain-containing protein 1. (331 aa)
	N300_05150	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1181 aa)
	N300_09977	Hyaluronidase. (418 aa)
	N300_01993	Thrombospondin-1. (1107 aa)
	N300_01952	Inactive serine protease PAMR1; Belongs to the peptidase S1 family. (695 aa)
	N300_12906	Metalloendopeptidase. (668 aa)
	N300_07639	Multiple epidermal growth factor-like domains protein 10. (1130 aa)
	N300_02129	Amphiregulin. (146 aa)
	N300_08787	Neurogenic locus notch protein. (560 aa)
	N300_11125	Uromodulin-like 1. (1305 aa)
	N300_03604	Contactin-associated protein-like 5. (952 aa)
	N300_12331	Cryptic protein. (188 aa)
	N300_02128	Proepiregulin. (118 aa)
	N300_10837	Cartilage matrix protein. (550 aa)
	N300_07739	Oncoprotein-induced transcript 3 protein. (535 aa)
	N300_03638	Integrin beta. (722 aa)
	N300_06297	Low-density lipoprotein receptor-related protein 5. (1540 aa)
	N300_12300	Protein NEL. (756 aa)
	N300_10159	Slit 2 protein. (1142 aa)
	N300_11960	E-selectin. (563 aa)
	N300_03640	Protein HEG 1. (362 aa)
	N300_12217	Protein delta 2. (332 aa)
	N300_01101	Interphotoreceptor matrix proteoglycan 1. (858 aa)
	N300_10514	Tomoregulin-1. (316 aa)
	N300_13429	Pancreatic secretory granule membrane major glycoprotein GP2. (422 aa)
	N300_02397	Thrombospondin-3. (857 aa)
	N300_02649	Tenascin-R. (1359 aa)
	N300_02652	Astrotactin-1. (1204 aa)
	N300_02640	Protein FAM5C. (766 aa)
	N300_12222	Latent-transforming growth factor beta-binding protein 1. (1319 aa)
	N300_12723	Angiopoietin-1 receptor. (1111 aa)
	N300_12695	Sushi domain-containing protein 1. (636 aa)
	N300_03029	Low-density lipoprotein receptor-related protein 1B. (179 aa)
	N300_01035	Integrin beta. (696 aa)

Your Current Organism:

Calypte anna

NCBI taxonomy Id: 9244
Other names: C. anna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N300_00373	N300_09681	A0A091IKM9	A0A091HJT6	Hyaluronidase.	Sortilin-related receptor.	0.452
N300_00373	N300_09977	A0A091IKM9	A0A091I9G5	Hyaluronidase.	Hyaluronidase.	0.771
N300_00396	N300_15302	A0A091HW93	A0A091HHV2	Cysteine-rich with EGF-like domain protein 2-A.	Matrilin-3.	0.561
N300_00805	N300_01798	A0A091IFS1	A0A091IFI8	Tyrosine-protein kinase receptor Tie-1.	Hepatocyte growth factor activator.	0.431
N300_00805	N300_02649	A0A091IFS1	A0A091I2F2	Tyrosine-protein kinase receptor Tie-1.	Tenascin-R.	0.458
N300_00805	N300_04192	A0A091IFS1	A0A091HW99	Tyrosine-protein kinase receptor Tie-1.	Teneurin-3.	0.526
N300_00805	N300_04611	A0A091IFS1	A0A091HQ83	Tyrosine-protein kinase receptor Tie-1.	Hyaluronan-binding protein 2.	0.431
N300_00805	N300_04668	A0A091IFS1	A0A091HXL4	Tyrosine-protein kinase receptor Tie-1.	Teneurin-1.	0.526
N300_00805	N300_05150	A0A091IFS1	A0A091I9H8	Tyrosine-protein kinase receptor Tie-1.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.804
N300_00805	N300_07414	A0A091IFS1	A0A091HW91	Tyrosine-protein kinase receptor Tie-1.	Pikachurin.	0.421
N300_00805	N300_07970	A0A091IFS1	A0A091IZQ2	Tyrosine-protein kinase receptor Tie-1.	Tenascin-R.	0.458
N300_00805	N300_09094	A0A091IFS1	A0A091IQM7	Tyrosine-protein kinase receptor Tie-1.	Teneurin-4.	0.526
N300_00805	N300_12723	A0A091IFS1	A0A091I1N2	Tyrosine-protein kinase receptor Tie-1.	Angiopoietin-1 receptor.	0.552
N300_01004	N300_01006	A0A091HXV3	A0A091IN90	Von Willebrand factor D and EGF domain-containing protein.	Von Willebrand factor D and EGF domain-containing protein.	0.838
N300_01004	N300_01035	A0A091HXV3	A0A091I146	Von Willebrand factor D and EGF domain-containing protein.	Integrin beta.	0.455
N300_01004	N300_01721	A0A091HXV3	A0A091IFA1	Von Willebrand factor D and EGF domain-containing protein.	Protocadherin Fat 3.	0.401
N300_01004	N300_02649	A0A091HXV3	A0A091I2F2	Von Willebrand factor D and EGF domain-containing protein.	Tenascin-R.	0.446
N300_01004	N300_03024	A0A091HXV3	A0A091I1E2	Von Willebrand factor D and EGF domain-containing protein.	Von Willebrand factor D and EGF domain-containing protein.	0.595
N300_01004	N300_07414	A0A091HXV3	A0A091HW91	Von Willebrand factor D and EGF domain-containing protein.	Pikachurin.	0.444
N300_01004	N300_07970	A0A091HXV3	A0A091IZQ2	Von Willebrand factor D and EGF domain-containing protein.	Tenascin-R.	0.446