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N300_11166 N300_11166 N300_11149 N300_11149 N300_13195 N300_13195 N300_06246 N300_06246 N300_10813 N300_10813 N300_00910 N300_00910 N300_03102 N300_03102 N300_01928 N300_01928 N300_08910 N300_08910 N300_10658 N300_10658 N300_13962 N300_13962 N300_09239 N300_09239 N300_13961 N300_13961 N300_12960 N300_12960 N300_14219 N300_14219 N300_12320 N300_12320 N300_09143 N300_09143 N300_06608 N300_06608 N300_12051 N300_12051 N300_04320 N300_04320 N300_08176 N300_08176 N300_06813 N300_06813 N300_05210 N300_05210 N300_03475 N300_03475 N300_12210 N300_12210 N300_14471 N300_14471 N300_03180 N300_03180 N300_03785 N300_03785 N300_05211 N300_05211 N300_09018 N300_09018 N300_06153 N300_06153 N300_01814 N300_01814 N300_06812 N300_06812 N300_04345 N300_04345 N300_06876 N300_06876 N300_05213 N300_05213 N300_13768 N300_13768 N300_05971 N300_05971 N300_03690 N300_03690 N300_14516 N300_14516 N300_00631 N300_00631 N300_09408 N300_09408 N300_10770 N300_10770 N300_10855 N300_10855 N300_04895 N300_04895 N300_13669 N300_13669 N300_00994 N300_00994 N300_02363 N300_02363 N300_05056 N300_05056
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
N300_11166DNA repair protein RAD51 3. (366 aa)
N300_11149Fanconi anemia group J protein. (1221 aa)
N300_13195Fanconi anemia group M protein. (1864 aa)
N300_06246E3 ubiquitin-protein ligase FANCL. (332 aa)
N300_10813Transcription cofactor HES-6. (226 aa)
N300_00910Spindle assembly abnormal protein 6. (645 aa)
N300_03102Mismatch repair endonuclease PMS2. (867 aa)
N300_01928Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2666 aa)
N300_08910RecQ-mediated genome instability protein 2. (49 aa)
N300_10658DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
N300_13962Protein-methionine sulfoxide oxidase MICAL3. (393 aa)
N300_09239RecQ-mediated genome instability protein 1. (622 aa)
N300_13961Protein-methionine sulfoxide oxidase MICAL3. (971 aa)
N300_12960Glutamine-rich protein 2. (163 aa)
N300_14219Partner and localizer of BRCA2. (535 aa)
N300_12320Fanconi anemia group C protein. (558 aa)
N300_09143Fanconi anemia group A protein. (1441 aa)
N300_06608Fanconi anemia group F protein. (359 aa)
N300_12051WD repeat-containing protein 48. (661 aa)
N300_04320Poly(A) RNA polymerase GLD2. (504 aa)
N300_08176DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (839 aa)
N300_06813Structure-specific endonuclease subunit SLX4. (222 aa)
N300_05210NEDD4-binding protein 2-like 2. (644 aa)
N300_03475Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (611 aa)
N300_12210DNA polymerase eta. (532 aa)
N300_14471Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1023 aa)
N300_03180DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1254 aa)
N300_03785Fanconi anemia group E protein. (515 aa)
N300_05211Uncharacterized protein. (148 aa)
N300_09018DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (989 aa)
N300_061532',3'-cyclic-nucleotide 3'-phosphodiesterase. (419 aa)
N300_01814DNA polymerase nu. (664 aa)
N300_06812Structure-specific endonuclease subunit SLX4. (417 aa)
N300_04345DNA polymerase kappa. (819 aa)
N300_06876Telomere length regulation protein TEL2. (686 aa)
N300_05213Breast cancer type 2 susceptibility protein. (3349 aa)
N300_13768Fanconi anemia group I protein. (1339 aa)
N300_05971Centromere protein S. (115 aa)
N300_03690Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (128 aa)
N300_14516Fanconi anemia group G protein. (582 aa)
N300_00631Ubiquitin carboxyl-terminal hydrolase. (773 aa)
N300_09408PITH domain-containing protein 1. (146 aa)
N300_10770DNA polymerase zeta catalytic subunit. (3119 aa)
N300_10855Replication protein A 32 kDa subunit. (237 aa)
N300_04895Crossover junction endonuclease EME1. (391 aa)
N300_13669Nuclear transport factor 2. (127 aa)
N300_00994Replication protein A 14 kDa subunit. (116 aa)
N300_02363Fanconi anemia group B protein. (867 aa)
N300_05056Fanconi anemia-associated protein of 100 kDa. (351 aa)
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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