STRINGSTRING
XRCC3 XRCC3 NBN NBN RHNO1 RHNO1 MEIOB MEIOB F6SF41_ORNAN F6SF41_ORNAN RECQL4 RECQL4 F7FJ30_ORNAN F7FJ30_ORNAN RPA2 RPA2 F6TW00_ORNAN F6TW00_ORNAN XRCC2 XRCC2 ATM ATM TOPBP1 TOPBP1 RAD50 RAD50 F7EW15_ORNAN F7EW15_ORNAN RAD51C RAD51C CDCA7 CDCA7 F7EUB7_ORNAN F7EUB7_ORNAN RBBP8 RBBP8 RAD51 RAD51 SPO11 SPO11 BLM BLM SLX4 SLX4 TOP3A TOP3A F7FDD9_ORNAN F7FDD9_ORNAN F6YT00_ORNAN F6YT00_ORNAN MRE11 MRE11 DMC1 DMC1 RPA1 RPA1 RMI1 RMI1 SLF1 SLF1 F7FCF8_ORNAN F7FCF8_ORNAN F6REC2_ORNAN F6REC2_ORNAN BRIP1 BRIP1 F6S5D8_ORNAN F6S5D8_ORNAN F6S2J0_ORNAN F6S2J0_ORNAN ATR ATR RAD52 RAD52 FANCM FANCM RAD1 RAD1 DNA2 DNA2 BRCA2 BRCA2 F7FYD7_ORNAN F7FYD7_ORNAN RECQL5 RECQL5 F7BS27_ORNAN F7BS27_ORNAN F7BR51_ORNAN F7BR51_ORNAN HUS1 HUS1 RAD9B RAD9B K7E6M7_ORNAN K7E6M7_ORNAN K7E739_ORNAN K7E739_ORNAN K7E7M8_ORNAN K7E7M8_ORNAN K7E7U9_ORNAN K7E7U9_ORNAN K7E8C1_ORNAN K7E8C1_ORNAN K7E8M8_ORNAN K7E8M8_ORNAN K7E9F1_ORNAN K7E9F1_ORNAN K7E9H4_ORNAN K7E9H4_ORNAN K7EAF2_ORNAN K7EAF2_ORNAN TDRD3 TDRD3 BRCA1 BRCA1 TOP3B TOP3B K7ED80_ORNAN K7ED80_ORNAN K7EDF8_ORNAN K7EDF8_ORNAN K7EDU9_ORNAN K7EDU9_ORNAN MUS81 MUS81 K7EEM2_ORNAN K7EEM2_ORNAN K7EF33_ORNAN K7EF33_ORNAN K7EF63_ORNAN K7EF63_ORNAN GEN1 GEN1 K7EFM5_ORNAN K7EFM5_ORNAN K7EGF0_ORNAN K7EGF0_ORNAN K7EGM5_ORNAN K7EGM5_ORNAN BARD1 BARD1 K7EH22_ORNAN K7EH22_ORNAN K7EHG7_ORNAN K7EHG7_ORNAN K7EHS6_ORNAN K7EHS6_ORNAN K7EI12_ORNAN K7EI12_ORNAN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (361 aa)
NBNUncharacterized protein. (396 aa)
RHNO1Uncharacterized protein. (246 aa)
MEIOBMeiosis specific with OB-fold. (472 aa)
F6SF41_ORNANERCC4 domain-containing protein. (454 aa)
RECQL4RecQ like helicase 4. (1188 aa)
F7FJ30_ORNANUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1020 aa)
RPA2Replication protein A2. (235 aa)
F6TW00_ORNANUncharacterized protein. (804 aa)
XRCC2X-ray repair cross complementing 2. (278 aa)
ATMFAT domain-containing protein. (1029 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1532 aa)
RAD50Zinc-hook domain-containing protein. (1209 aa)
F7EW15_ORNANXPGI domain-containing protein. (807 aa)
RAD51CRAD51 paralog C. (458 aa)
CDCA7Cell division cycle associated 7. (451 aa)
F7EUB7_ORNANUncharacterized protein. (1260 aa)
RBBP8Uncharacterized protein. (569 aa)
RAD51Uncharacterized protein. (119 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (392 aa)
BLMATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (769 aa)
SLX4Uncharacterized protein. (1178 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (940 aa)
F7FDD9_ORNANDna2 domain-containing protein. (341 aa)
F6YT00_ORNANWD_REPEATS_REGION domain-containing protein. (1091 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (624 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (333 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
RMI1RecQ mediated genome instability 1. (612 aa)
SLF1SMC5-SMC6 complex localization factor 1. (925 aa)
F7FCF8_ORNANUncharacterized protein. (688 aa)
F6REC2_ORNANUncharacterized protein. (285 aa)
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1220 aa)
F6S5D8_ORNANTudor domain-containing protein. (368 aa)
F6S2J0_ORNANUncharacterized protein. (194 aa)
ATRUncharacterized protein. (473 aa)
RAD52Uncharacterized protein. (95 aa)
FANCMUncharacterized protein. (1951 aa)
RAD1RAD1 checkpoint DNA exonuclease. (281 aa)
DNA2Uncharacterized protein. (567 aa)
BRCA2Tower domain-containing protein. (3459 aa)
F7FYD7_ORNANUncharacterized protein. (519 aa)
RECQL5Uncharacterized protein. (413 aa)
F7BS27_ORNANUncharacterized protein. (122 aa)
F7BR51_ORNANNbs1_C domain-containing protein. (284 aa)
HUS1Uncharacterized protein. (91 aa)
RAD9BUncharacterized protein. (253 aa)
K7E6M7_ORNANUncharacterized protein. (389 aa)
K7E739_ORNANUME domain-containing protein. (306 aa)
K7E7M8_ORNANUncharacterized protein. (181 aa)
K7E7U9_ORNANPI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (77 aa)
K7E8C1_ORNANUncharacterized protein. (85 aa)
K7E8M8_ORNANRECA_2 domain-containing protein. (216 aa)
K7E9F1_ORNANRING-type domain-containing protein. (145 aa)
K7E9H4_ORNANzf-RING_6 domain-containing protein. (95 aa)
K7EAF2_ORNANSAE2 domain-containing protein. (183 aa)
TDRD3UBA domain-containing protein. (203 aa)
BRCA1Uncharacterized protein. (208 aa)
TOP3BDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (125 aa)
K7ED80_ORNANCtIP_N domain-containing protein. (108 aa)
K7EDF8_ORNANUncharacterized protein. (85 aa)
K7EDU9_ORNANERCC4 domain-containing protein. (133 aa)
MUS81Uncharacterized protein. (135 aa)
K7EEM2_ORNANUncharacterized protein. (75 aa)
K7EF33_ORNANUncharacterized protein. (95 aa)
K7EF63_ORNANTower domain-containing protein. (94 aa)
GEN1Uncharacterized protein. (132 aa)
K7EFM5_ORNANANK_REP_REGION domain-containing protein. (85 aa)
K7EGF0_ORNAN3'-5' exonuclease domain-containing protein. (79 aa)
K7EGM5_ORNANFHA domain-containing protein. (142 aa)
BARD1Uncharacterized protein. (205 aa)
K7EH22_ORNANUncharacterized protein. (142 aa)
K7EHG7_ORNANUncharacterized protein. (146 aa)
K7EHS6_ORNANFAT domain-containing protein. (138 aa)
K7EI12_ORNANUncharacterized protein. (73 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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