(18 nodes) BRCA1-C complex, and Double-strand/single-strand DNA junction binding network (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NBN	Uncharacterized protein. (396 aa)
	ATM	FAT domain-containing protein. (1029 aa)
	RAD50	Zinc-hook domain-containing protein. (1209 aa)
	F7EUB7_ORNAN	Uncharacterized protein. (1260 aa)
	RBBP8	Uncharacterized protein. (569 aa)
	MRE11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (624 aa)
	SLF1	SMC5-SMC6 complex localization factor 1. (925 aa)
	F7BR51_ORNAN	Nbs1_C domain-containing protein. (284 aa)
	K7E9F1_ORNAN	RING-type domain-containing protein. (145 aa)
	K7E9H4_ORNAN	zf-RING_6 domain-containing protein. (95 aa)
	K7EAF2_ORNAN	SAE2 domain-containing protein. (183 aa)
	BRCA1	Uncharacterized protein. (208 aa)
	K7ED80_ORNAN	CtIP_N domain-containing protein. (108 aa)
	K7EF63_ORNAN	Tower domain-containing protein. (94 aa)
	K7EFM5_ORNAN	ANK_REP_REGION domain-containing protein. (85 aa)
	K7EGM5_ORNAN	FHA domain-containing protein. (142 aa)
	BARD1	Uncharacterized protein. (205 aa)
	K7EH22_ORNAN	Uncharacterized protein. (142 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	BARD1	ENSOANP00000009993	ENSOANP00000032797	FAT domain-containing protein.	Uncharacterized protein.	0.703
ATM	BRCA1	ENSOANP00000009993	ENSOANP00000031186	FAT domain-containing protein.	Uncharacterized protein.	0.984
ATM	F7BR51_ORNAN	ENSOANP00000009993	ENSOANP00000025285	FAT domain-containing protein.	Nbs1_C domain-containing protein.	0.610
ATM	F7EUB7_ORNAN	ENSOANP00000009993	ENSOANP00000014344	FAT domain-containing protein.	Uncharacterized protein.	0.579
ATM	K7E9F1_ORNAN	ENSOANP00000009993	ENSOANP00000030158	FAT domain-containing protein.	RING-type domain-containing protein.	0.575
ATM	K7E9H4_ORNAN	ENSOANP00000009993	ENSOANP00000030181	FAT domain-containing protein.	zf-RING_6 domain-containing protein.	0.561
ATM	K7EAF2_ORNAN	ENSOANP00000009993	ENSOANP00000030509	FAT domain-containing protein.	SAE2 domain-containing protein.	0.409
ATM	K7ED80_ORNAN	ENSOANP00000009993	ENSOANP00000031487	FAT domain-containing protein.	CtIP_N domain-containing protein.	0.409
ATM	K7EF63_ORNAN	ENSOANP00000009993	ENSOANP00000032170	FAT domain-containing protein.	Tower domain-containing protein.	0.453
ATM	K7EFM5_ORNAN	ENSOANP00000009993	ENSOANP00000032332	FAT domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.561
ATM	K7EGM5_ORNAN	ENSOANP00000009993	ENSOANP00000032682	FAT domain-containing protein.	FHA domain-containing protein.	0.610
ATM	K7EH22_ORNAN	ENSOANP00000009993	ENSOANP00000032829	FAT domain-containing protein.	Uncharacterized protein.	0.602
ATM	MRE11	ENSOANP00000009993	ENSOANP00000016491	FAT domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.974
ATM	NBN	ENSOANP00000009993	ENSOANP00000002103	FAT domain-containing protein.	Uncharacterized protein.	0.959
ATM	RAD50	ENSOANP00000009993	ENSOANP00000012752	FAT domain-containing protein.	Zinc-hook domain-containing protein.	0.958
ATM	RBBP8	ENSOANP00000009993	ENSOANP00000014622	FAT domain-containing protein.	Uncharacterized protein.	0.505
ATM	SLF1	ENSOANP00000009993	ENSOANP00000017528	FAT domain-containing protein.	SMC5-SMC6 complex localization factor 1.	0.629
BARD1	ATM	ENSOANP00000032797	ENSOANP00000009993	Uncharacterized protein.	FAT domain-containing protein.	0.703
BARD1	BRCA1	ENSOANP00000032797	ENSOANP00000031186	Uncharacterized protein.	Uncharacterized protein.	0.988
BARD1	F7BR51_ORNAN	ENSOANP00000032797	ENSOANP00000025285	Uncharacterized protein.	Nbs1_C domain-containing protein.	0.750