STRINGSTRING
MCM10 MCM10 CHTF18 CHTF18 ORC3 ORC3 F7EMZ8_ORNAN F7EMZ8_ORNAN F7D200_ORNAN F7D200_ORNAN RAD17 RAD17 STN1 STN1 POLI POLI TEN1 TEN1 CLSPN CLSPN POLH POLH MCMDC2 MCMDC2 CHTF8 CHTF8 LIG1 LIG1 F7FJN1_ORNAN F7FJN1_ORNAN ORC6 ORC6 F7AUC8_ORNAN F7AUC8_ORNAN F6S2Y0_ORNAN F6S2Y0_ORNAN F7AR20_ORNAN F7AR20_ORNAN REV1 REV1 DBF4 DBF4 ATAD5 ATAD5 F7CRP1_ORNAN F7CRP1_ORNAN F7CQ71_ORNAN F7CQ71_ORNAN F6WX64_ORNAN F6WX64_ORNAN POLD2 POLD2 GINS4 GINS4 POLD3 POLD3 MCM9-2 MCM9-2 MCM2 MCM2 MCM4 MCM4 RFC2 RFC2 FEN1 FEN1 MCM6 MCM6 F7F484_ORNAN F7F484_ORNAN ORC4 ORC4 MCM8 MCM8 DTL DTL MCM9 MCM9 F6TS55_ORNAN F6TS55_ORNAN TIPIN TIPIN REV3L REV3L F6ZQP9_ORNAN F6ZQP9_ORNAN ORC2 ORC2 RFC1 RFC1 WDHD1 WDHD1 POLE POLE MCM5 MCM5 GINS2 GINS2 POLE4 POLE4 GINS3 GINS3 TIMELESS TIMELESS RFC4 RFC4 PRIM2 PRIM2 F6S822_ORNAN F6S822_ORNAN F7E3J1_ORNAN F7E3J1_ORNAN MCMBP MCMBP POLE2 POLE2 F6XC55_ORNAN F6XC55_ORNAN CDC7 CDC7 ORC5 ORC5 F6WWQ7_ORNAN F6WWQ7_ORNAN CDC6 CDC6 RFC3 RFC3 F7B8L0_ORNAN F7B8L0_ORNAN POLK POLK F6XP74_ORNAN F6XP74_ORNAN MAD2L2 MAD2L2 F7BRC7_ORNAN F7BRC7_ORNAN F6VQA8_ORNAN F6VQA8_ORNAN F7G0R7_ORNAN F7G0R7_ORNAN F6Y8M5_ORNAN F6Y8M5_ORNAN F6QIT2_ORNAN F6QIT2_ORNAN ENSOANP00000029145 ENSOANP00000029145 K7E8H6_ORNAN K7E8H6_ORNAN K7E8J2_ORNAN K7E8J2_ORNAN POLE-2 POLE-2 ENSOANP00000029989 ENSOANP00000029989 MCM3 MCM3 CDC45 CDC45 K7ECA8_ORNAN K7ECA8_ORNAN K7ECT5_ORNAN K7ECT5_ORNAN K7ED41_ORNAN K7ED41_ORNAN POLA2 POLA2 K7EDP7_ORNAN K7EDP7_ORNAN POLD1 POLD1 GINS1 GINS1 K7EF39_ORNAN K7EF39_ORNAN K7EFV9_ORNAN K7EFV9_ORNAN ENSOANP00000032425 ENSOANP00000032425 K7EGE3_ORNAN K7EGE3_ORNAN K7EIB3_ORNAN K7EIB3_ORNAN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM10Minichromosome maintenance 10 replication initiation factor. (882 aa)
CHTF18Uncharacterized protein. (486 aa)
ORC3Origin recognition complex subunit 3. (616 aa)
F7EMZ8_ORNANDNA_pol_B_exo1 domain-containing protein. (225 aa)
F7D200_ORNANUncharacterized protein. (384 aa)
RAD17Uncharacterized protein. (680 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (370 aa)
POLIDNA polymerase iota. (716 aa)
TEN1Uncharacterized protein. (128 aa)
CLSPNClaspin. (1275 aa)
POLHDNA polymerase eta. (729 aa)
MCMDC2Minichromosome maintenance domain containing 2. (681 aa)
CHTF8Chromosome transmission fidelity factor 8. (122 aa)
LIG1DNA ligase. (828 aa)
F7FJN1_ORNANAAA domain-containing protein. (350 aa)
ORC6Origin recognition complex subunit 6. (263 aa)
F7AUC8_ORNANUncharacterized protein. (170 aa)
F6S2Y0_ORNANUncharacterized protein. (58 aa)
F7AR20_ORNANUncharacterized protein. (257 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1269 aa)
DBF4DBF4-type domain-containing protein. (405 aa)
ATAD5ATPase family AAA domain containing 5. (1831 aa)
F7CRP1_ORNANDNA_pol_B domain-containing protein. (83 aa)
F7CQ71_ORNANDNA_pol_B domain-containing protein. (151 aa)
F6WX64_ORNANUncharacterized protein. (210 aa)
POLD2DNA polymerase delta 2, accessory subunit. (471 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa)
POLD3Uncharacterized protein. (125 aa)
MCM9-2Uncharacterized protein. (46 aa)
MCM2DNA helicase; Belongs to the MCM family. (908 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
RFC2Replication factor C subunit 2. (316 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (387 aa)
MCM6MCM domain-containing protein; Belongs to the MCM family. (741 aa)
F7F484_ORNANUncharacterized protein. (251 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (435 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (828 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (734 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1137 aa)
F6TS55_ORNANOrigin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (653 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (290 aa)
REV3LUncharacterized protein. (551 aa)
F6ZQP9_ORNANDUF4683 domain-containing protein. (360 aa)
ORC2Origin recognition complex subunit 2. (400 aa)
RFC1Replication factor C subunit 1. (1153 aa)
WDHD1HMG box domain-containing protein. (794 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1770 aa)
MCM5DNA helicase; Belongs to the MCM family. (609 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (155 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (107 aa)
GINS3GINS complex subunit 3. (216 aa)
TIMELESSTimeless circadian regulator. (1141 aa)
RFC4Replication factor C subunit 4. (228 aa)
PRIM2Uncharacterized protein. (164 aa)
F6S822_ORNANUncharacterized protein. (279 aa)
F7E3J1_ORNANCDT1 domain-containing protein. (445 aa)
MCMBPUncharacterized protein. (146 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
F6XC55_ORNANDNA_pol_E_B domain-containing protein. (472 aa)
CDC7Cell division cycle 7; Belongs to the protein kinase superfamily. (410 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
F6WWQ7_ORNANWD_REPEATS_REGION domain-containing protein. (267 aa)
CDC6AAA domain-containing protein. (372 aa)
RFC3Replication factor C subunit 3. (356 aa)
F7B8L0_ORNANUncharacterized protein. (742 aa)
POLKDNA polymerase kappa. (876 aa)
F6XP74_ORNANUncharacterized protein. (178 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (286 aa)
F7BRC7_ORNANProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (214 aa)
F6VQA8_ORNANATPase_AAA_core domain-containing protein. (93 aa)
F7G0R7_ORNANUncharacterized protein. (377 aa)
F6Y8M5_ORNANDBF4-type domain-containing protein. (276 aa)
F6QIT2_ORNANUncharacterized protein. (155 aa)
ENSOANP00000029145annotation not available (79 aa)
K7E8H6_ORNANUncharacterized protein. (95 aa)
K7E8J2_ORNANUncharacterized protein. (75 aa)
POLE-2DNA polymerase epsilon catalytic subunit A isoform X1. (127 aa)
ENSOANP00000029989annotation not available (91 aa)
MCM3MCM_OB domain-containing protein. (192 aa)
CDC45Uncharacterized protein. (146 aa)
K7ECA8_ORNANUncharacterized protein. (151 aa)
K7ECT5_ORNANUncharacterized protein. (70 aa)
K7ED41_ORNANCdc6_C domain-containing protein. (115 aa)
POLA2Uncharacterized protein. (95 aa)
K7EDP7_ORNANUncharacterized protein. (101 aa)
POLD1DNA polymerase. (287 aa)
GINS1Sld5 domain-containing protein. (72 aa)
K7EF39_ORNANDNA_pol_B domain-containing protein. (96 aa)
K7EFV9_ORNANUncharacterized protein. (126 aa)
ENSOANP00000032425annotation not available (59 aa)
K7EGE3_ORNANUncharacterized protein. (94 aa)
K7EIB3_ORNANDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (137 aa)
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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