50 items (Ornithorhynchus anatinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHTF18	Uncharacterized protein. (486 aa)
	F7EMZ8_ORNAN	DNA_pol_B_exo1 domain-containing protein. (225 aa)
	RAD17	Uncharacterized protein. (680 aa)
	STN1	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (370 aa)
	POLI	DNA polymerase iota. (716 aa)
	TEN1	Uncharacterized protein. (128 aa)
	POLH	DNA polymerase eta. (729 aa)
	CHTF8	Chromosome transmission fidelity factor 8. (122 aa)
	LIG1	DNA ligase. (828 aa)
	F7FJN1_ORNAN	AAA domain-containing protein. (350 aa)
	F6S2Y0_ORNAN	Uncharacterized protein. (58 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1269 aa)
	ATAD5	ATPase family AAA domain containing 5. (1831 aa)
	F7CRP1_ORNAN	DNA_pol_B domain-containing protein. (83 aa)
	F7CQ71_ORNAN	DNA_pol_B domain-containing protein. (151 aa)
	F6WX64_ORNAN	Uncharacterized protein. (210 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (471 aa)
	POLD3	Uncharacterized protein. (125 aa)
	RFC2	Replication factor C subunit 2. (316 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (387 aa)
	F7F484_ORNAN	Uncharacterized protein. (251 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (734 aa)
	REV3L	Uncharacterized protein. (551 aa)
	F6ZQP9_ORNAN	DUF4683 domain-containing protein. (360 aa)
	RFC1	Replication factor C subunit 1. (1153 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1770 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (107 aa)
	RFC4	Replication factor C subunit 4. (228 aa)
	PRIM2	Uncharacterized protein. (164 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
	F6XC55_ORNAN	DNA_pol_E_B domain-containing protein. (472 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	F7B8L0_ORNAN	Uncharacterized protein. (742 aa)
	POLK	DNA polymerase kappa. (876 aa)
	F6XP74_ORNAN	Uncharacterized protein. (178 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (286 aa)
	F7BRC7_ORNAN	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (214 aa)
	F6VQA8_ORNAN	ATPase_AAA_core domain-containing protein. (93 aa)
	F6QIT2_ORNAN	Uncharacterized protein. (155 aa)
	K7E8H6_ORNAN	Uncharacterized protein. (95 aa)
	POLE-2	DNA polymerase epsilon catalytic subunit A isoform X1. (127 aa)
	ENSOANP00000029989	annotation not available (91 aa)
	POLA2	Uncharacterized protein. (95 aa)
	K7EDP7_ORNAN	Uncharacterized protein. (101 aa)
	POLD1	DNA polymerase. (287 aa)
	K7EF39_ORNAN	DNA_pol_B domain-containing protein. (96 aa)
	K7EFV9_ORNAN	Uncharacterized protein. (126 aa)
	ENSOANP00000032425	annotation not available (59 aa)
	K7EGE3_ORNAN	Uncharacterized protein. (94 aa)
	K7EIB3_ORNAN	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (137 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CHTF18	ENSOANP00000008353	ENSOANP00000000739	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.671
ATAD5	CHTF8	ENSOANP00000008353	ENSOANP00000003739	ATPase family AAA domain containing 5.	Chromosome transmission fidelity factor 8.	0.568
ATAD5	DTL	ENSOANP00000008353	ENSOANP00000013502	ATPase family AAA domain containing 5.	Denticleless E3 ubiquitin protein ligase homolog.	0.702
ATAD5	ENSOANP00000032425	ENSOANP00000008353	ENSOANP00000032425	ATPase family AAA domain containing 5.	annotation not available	0.605
ATAD5	F6QIT2_ORNAN	ENSOANP00000008353	ENSOANP00000028991	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.684
ATAD5	F6S2Y0_ORNAN	ENSOANP00000008353	ENSOANP00000006890	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.470
ATAD5	F6VQA8_ORNAN	ENSOANP00000008353	ENSOANP00000025991	ATPase family AAA domain containing 5.	ATPase_AAA_core domain-containing protein.	0.835
ATAD5	F6WX64_ORNAN	ENSOANP00000008353	ENSOANP00000009530	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.556
ATAD5	F6XC55_ORNAN	ENSOANP00000008353	ENSOANP00000022420	ATPase family AAA domain containing 5.	DNA_pol_E_B domain-containing protein.	0.613
ATAD5	F6XP74_ORNAN	ENSOANP00000008353	ENSOANP00000025138	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.916
ATAD5	F6ZQP9_ORNAN	ENSOANP00000008353	ENSOANP00000015848	ATPase family AAA domain containing 5.	DUF4683 domain-containing protein.	0.470
ATAD5	F7B8L0_ORNAN	ENSOANP00000008353	ENSOANP00000024389	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.420
ATAD5	F7BRC7_ORNAN	ENSOANP00000008353	ENSOANP00000025275	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.900
ATAD5	F7CQ71_ORNAN	ENSOANP00000008353	ENSOANP00000008655	ATPase family AAA domain containing 5.	DNA_pol_B domain-containing protein.	0.470
ATAD5	F7CRP1_ORNAN	ENSOANP00000008353	ENSOANP00000008451	ATPase family AAA domain containing 5.	DNA_pol_B domain-containing protein.	0.470
ATAD5	F7EMZ8_ORNAN	ENSOANP00000008353	ENSOANP00000000999	ATPase family AAA domain containing 5.	DNA_pol_B_exo1 domain-containing protein.	0.470
ATAD5	F7F484_ORNAN	ENSOANP00000008353	ENSOANP00000012906	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.696
ATAD5	F7FJN1_ORNAN	ENSOANP00000008353	ENSOANP00000005764	ATPase family AAA domain containing 5.	AAA domain-containing protein.	0.671
ATAD5	FEN1	ENSOANP00000008353	ENSOANP00000012510	ATPase family AAA domain containing 5.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.841
ATAD5	K7E8H6_ORNAN	ENSOANP00000008353	ENSOANP00000029833	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.556