(18 nodes) Telomere maintenance via recombination network (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TEP1	TROVE domain-containing protein. (212 aa)
	XRCC3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (361 aa)
	F6SUV9_ORNAN	SMC_N domain-containing protein. (340 aa)
	ERCC1	Uncharacterized protein. (310 aa)
	SMC5	SMC_N domain-containing protein. (1101 aa)
	RAD50	Zinc-hook domain-containing protein. (1209 aa)
	RAD51C	RAD51 paralog C. (458 aa)
	RAD51	Uncharacterized protein. (119 aa)
	SMC6	Uncharacterized protein. (603 aa)
	F6Y2M2_ORNAN	BRCT domain-containing protein. (449 aa)
	F7D8W7_ORNAN	Uncharacterized protein. (2295 aa)
	BRCA2	Tower domain-containing protein. (3459 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (807 aa)
	NSMCE2	SP-RING-type domain-containing protein. (91 aa)
	F6Y3L2_ORNAN	Uncharacterized protein; Belongs to the CGI121/TPRKB family. (147 aa)
	K7E8M8_ORNAN	RECA_2 domain-containing protein. (216 aa)
	K7EF63_ORNAN	Tower domain-containing protein. (94 aa)
	K7EH22_ORNAN	Uncharacterized protein. (142 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA2	ERCC1	ENSOANP00000024376	ENSOANP00000007190	Tower domain-containing protein.	Uncharacterized protein.	0.493
BRCA2	ERCC4	ENSOANP00000024376	ENSOANP00000025598	Tower domain-containing protein.	ERCC excision repair 4, endonuclease catalytic subunit.	0.491
BRCA2	F6Y2M2_ORNAN	ENSOANP00000024376	ENSOANP00000017067	Tower domain-containing protein.	BRCT domain-containing protein.	0.465
BRCA2	K7E8M8_ORNAN	ENSOANP00000024376	ENSOANP00000029885	Tower domain-containing protein.	RECA_2 domain-containing protein.	0.961
BRCA2	K7EH22_ORNAN	ENSOANP00000024376	ENSOANP00000032829	Tower domain-containing protein.	Uncharacterized protein.	0.459
BRCA2	RAD50	ENSOANP00000024376	ENSOANP00000012752	Tower domain-containing protein.	Zinc-hook domain-containing protein.	0.459
BRCA2	RAD51	ENSOANP00000024376	ENSOANP00000014708	Tower domain-containing protein.	Uncharacterized protein.	0.992
BRCA2	RAD51C	ENSOANP00000024376	ENSOANP00000013505	Tower domain-containing protein.	RAD51 paralog C.	0.991
BRCA2	XRCC3	ENSOANP00000024376	ENSOANP00000001227	Tower domain-containing protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.891
ERCC1	BRCA2	ENSOANP00000007190	ENSOANP00000024376	Uncharacterized protein.	Tower domain-containing protein.	0.493
ERCC1	ERCC4	ENSOANP00000007190	ENSOANP00000025598	Uncharacterized protein.	ERCC excision repair 4, endonuclease catalytic subunit.	0.999
ERCC1	F6Y2M2_ORNAN	ENSOANP00000007190	ENSOANP00000017067	Uncharacterized protein.	BRCT domain-containing protein.	0.609
ERCC1	K7E8M8_ORNAN	ENSOANP00000007190	ENSOANP00000029885	Uncharacterized protein.	RECA_2 domain-containing protein.	0.648
ERCC1	K7EF63_ORNAN	ENSOANP00000007190	ENSOANP00000032170	Uncharacterized protein.	Tower domain-containing protein.	0.493
ERCC1	K7EH22_ORNAN	ENSOANP00000007190	ENSOANP00000032829	Uncharacterized protein.	Uncharacterized protein.	0.426
ERCC1	RAD50	ENSOANP00000007190	ENSOANP00000012752	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.426
ERCC1	RAD51	ENSOANP00000007190	ENSOANP00000014708	Uncharacterized protein.	Uncharacterized protein.	0.623
ERCC1	RAD51C	ENSOANP00000007190	ENSOANP00000013505	Uncharacterized protein.	RAD51 paralog C.	0.601
ERCC1	XRCC3	ENSOANP00000007190	ENSOANP00000001227	Uncharacterized protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.634
ERCC4	BRCA2	ENSOANP00000025598	ENSOANP00000024376	ERCC excision repair 4, endonuclease catalytic subunit.	Tower domain-containing protein.	0.491